AutismKB 2.0

Annotation Detail for NAGPA


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Basic Information Top
Gene Symbol:NAGPA ( APAA,UCE )
Gene Full Name: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Band: 16p13.3
Quick LinksEntrez ID:51172; OMIM: 607985; Uniprot ID:NAGPA_HUMAN; ENSEMBL ID: ENSG00000103174; HGNC ID: 17378
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus13 / 56401223
neonate1 / 3109732
infant3 / 23620127
juvenile2 / 5555635
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal93 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow3 / 4880161
brain38 / 110098934
cervix11 / 48171228
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine11 / 23447246
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung9 / 33697426
lymph1 / 4427022
lymph node1 / 9161010
mammary gland8 / 15327152
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas11 / 21481251
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin6 / 21057428
spleen4 / 5395274
stomach1 / 9661910
testis6 / 33044218
thymus2 / 8113124
thyroid1 / 4747321
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205090_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.5
Adipocyte9
AdrenalCortex11
Adrenalgland9.15
Amygdala21.5
Appendix11.05
AtrioventricularNode8.5
BDCA4+_DentriticCells47.8
Bonemarrow10.8
BronchialEpithelialCells9.95
CD105+_Endothelial11.3
CD14+_Monocytes57
CD19+_BCells(neg._sel.)30.8
CD33+_Myeloid100.4
CD34+28.8
CD4+_Tcells25.55
CD56+_NKCells43.7
CD71+_EarlyErythroid10.15
CD8+_Tcells20.75
CardiacMyocytes13.2
Caudatenucleus19.25
Cerebellum8.95
CerebellumPeduncles11.55
CiliaryGanglion7.7
CingulateCortex33.15
Colorectaladenocarcinoma12.2
DorsalRootGanglion8.2
FetalThyroid10.7
Fetalbrain10.35
Fetalliver10.6
Fetallung8.5
GlobusPallidus10.55
Heart15.15
Hypothalamus11.3
Kidney8.8
Leukemia_chronicMyelogenousK-5629.85
Leukemia_promyelocytic-HL-609.05
Leukemialymphoblastic(MOLT-4)8.35
Liver14.45
Lung17.8
Lymphnode12.95
Lymphoma_burkitts(Daudi)12.3
Lymphoma_burkitts(Raji)15.05
MedullaOblongata22.35
OccipitalLobe32.55
OlfactoryBulb7.4
Ovary7.1
Pancreas7.5
PancreaticIslet8.95
ParietalLobe16.8
Pituitary12
Placenta11.2
Pons11.6
PrefrontalCortex54.15
Prostate12.5
Salivarygland7.95
SkeletalMuscle13.75
Skin8.25
SmoothMuscle12.1
Spinalcord14.3
SubthalamicNucleus15.15
SuperiorCervicalGanglion12.25
TemporalLobe18.6
Testis9
TestisGermCell7.6
TestisIntersitial9.1
TestisLeydigCell10.45
TestisSeminiferousTubule7.75
Thalamus11.15
Thymus14.25
Thyroid21.95
Tongue10.55
Tonsil9.8
Trachea8.1
TrigeminalGanglion10.75
Uterus7.7
UterusCorpus9.65
WholeBlood21.1
Wholebrain75.4
colon8.6
pineal_day10.12
pineal_night9.96
retina12.15
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P116571
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.15 ± 0.89
Basal Forebrain4.45 ± 0.35
Basal Part of Pons5.12 ± 0.6
Cerebellar Cortex4.58 ± 0.43
Cerebellar Nuclei4.36 ± 0.56
Claustrum4.6 ± 0.79
Epithalamus4.29 ± 0.74
Frontal Lobe5.12 ± 0.66
Globus Pallidus3.55 ± 1.01
Hypothalamus4.28 ± 0.41
Insula4.95 ± 0.65
Limbic Lobe5.53 ± 0.8
Mesencephalon4.87 ± 0.71
Myelencephalon4.93 ± 0.56
Occipital Lobe5.53 ± 0.57
Parietal Lobe5.29 ± 0.56
Pontine Tegmentum4.93 ± 0.65
Striatum5.13 ± 0.77
Subthalamus4.99 ± 0.71
Temporal Lobe5.29 ± 0.54
Thalamus4.71 ± 0.54
White Matter3.26 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NagpaCBCerebellum1.97
3.02
NagpaCTXCerebral cortex8.8
7.64
NagpaHIPHippocampal region6.75
7.15
NagpaHPFHippocampal formation5.63
5.62
NagpaHYHypothalamus0.65
0.91
NagpaLSXLateral septal complex0.97
0.97
NagpaMBMidbrain2.12
3.82
NagpaMYMedulla1.37
3.35
NagpaOLFOlfactory bulb4.2
4.48
NagpaPPons2.55
6.38
NagpaPALPallidum0.95
1.39
NagpaRHPRetrohippocampal region2.61
2.63
NagpasAMYStriatum-like amygdalar nuclei0.68
1.31
NagpaSTRStriatum0.82
1.02
NagpaSTRdStriatum dorsal region0.86
0.94
NagpaSTRvStriatum ventral region0.82
1.17
NagpaTHThalamus2.52
2.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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