AutismKB 2.0

Annotation Detail for CKLF


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Basic Information Top
Gene Symbol:CKLF ( C32,CKLF1,CKLF2,CKLF3,CKLF4,UCK-1 )
Gene Full Name: chemokine-like factor
Band: 16q21
Quick LinksEntrez ID:51192; OMIM: NA; Uniprot ID:CKLF_HUMAN; ENSEMBL ID: ENSG00000217555; HGNC ID: 13253
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor8 / 26384530
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal93 / 336030727
ovarian tumor4 / 7668252
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood10 / 12347880
bone2 / 7165527
bone marrow2 / 4880140
brain18 / 110098916
cervix0 / 481710 
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart6 / 8962666
intestine8 / 23447234
kidney5 / 21177723
larynx1 / 2414541
liver5 / 20774324
lung12 / 33697435
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas17 / 21481279
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach1 / 9661910
testis17 / 33044251
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219161_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts74.6
Adipocyte10.5
AdrenalCortex8.5
Adrenalgland9.2
Amygdala7.5
Appendix9.1
AtrioventricularNode6.3
BDCA4+_DentriticCells127.3
Bonemarrow93.05
BronchialEpithelialCells10.45
CD105+_Endothelial28.15
CD14+_Monocytes390.45
CD19+_BCells(neg._sel.)73.6
CD33+_Myeloid475.6
CD34+40.35
CD4+_Tcells72
CD56+_NKCells290.7
CD71+_EarlyErythroid7.25
CD8+_Tcells107
CardiacMyocytes11.95
Caudatenucleus7.45
Cerebellum6.25
CerebellumPeduncles9.35
CiliaryGanglion5.9
CingulateCortex7.65
Colorectaladenocarcinoma40.95
DorsalRootGanglion6.15
FetalThyroid7.55
Fetalbrain7.1
Fetalliver10.7
Fetallung9.85
GlobusPallidus5.55
Heart12.5
Hypothalamus8.3
Kidney6.55
Leukemia_chronicMyelogenousK-56218.75
Leukemia_promyelocytic-HL-607.45
Leukemialymphoblastic(MOLT-4)77.95
Liver10.9
Lung35
Lymphnode12.75
Lymphoma_burkitts(Daudi)21.65
Lymphoma_burkitts(Raji)13.35
MedullaOblongata7.15
OccipitalLobe6.9
OlfactoryBulb6.1
Ovary6.9
Pancreas6.2
PancreaticIslet11.3
ParietalLobe8.35
Pituitary8.8
Placenta7.7
Pons7.75
PrefrontalCortex8.05
Prostate8.75
Salivarygland6.7
SkeletalMuscle9.75
Skin6.25
SmoothMuscle9.7
Spinalcord8.45
SubthalamicNucleus7.1
SuperiorCervicalGanglion9.65
TemporalLobe7.15
Testis116.9
TestisGermCell13.65
TestisIntersitial23.85
TestisLeydigCell14.35
TestisSeminiferousTubule12.2
Thalamus8.3
Thymus55.25
Thyroid16.3
Tongue7.85
Tonsil8.2
Trachea7.95
TrigeminalGanglion11
Uterus9
UterusCorpus7.4
WholeBlood1434.4
Wholebrain7.05
colon101.6
pineal_day9.52
pineal_night9.16
retina11.45
small_intestine153.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P215804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.48 ± 1.1
Basal Forebrain2.11 ± 0.29
Basal Part of Pons2.07 ± 0.58
Cerebellar Cortex1.78 ± 0.77
Cerebellar Nuclei2.55 ± 0.74
Claustrum2.85 ± 0.78
Epithalamus1.85 ± 0.97
Frontal Lobe1.94 ± 0.77
Globus Pallidus2.61 ± 0.75
Hypothalamus2.02 ± 0.82
Insula2.11 ± 0.81
Limbic Lobe2 ± 0.77
Mesencephalon2.05 ± 0.74
Myelencephalon2.02 ± 0.7
Occipital Lobe1.95 ± 0.8
Parietal Lobe2.01 ± 0.76
Pontine Tegmentum2.08 ± 0.74
Striatum2.16 ± 0.72
Subthalamus2.14 ± 0.68
Temporal Lobe1.82 ± 0.65
Thalamus1.96 ± 0.61
White Matter2.57 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CklfCBCerebellum5.63
7.08
CklfCTXCerebral cortex9.65
7.43
CklfHIPHippocampal region4.27
4.06
CklfHPFHippocampal formation5.41
4.52
CklfHYHypothalamus1.07
0.93
CklfLSXLateral septal complex2.52
1.84
CklfMBMidbrain3.13
2.98
CklfMYMedulla7.67
8.22
CklfOLFOlfactory bulb14.86
12.5
CklfPPons4.66
4.92
CklfPALPallidum2.28
2.26
CklfRHPRetrohippocampal region7.74
5.45
CklfsAMYStriatum-like amygdalar nuclei1.16
1.2
CklfSTRStriatum2.97
2.41
CklfSTRdStriatum dorsal region3.87
3.2
CklfSTRvStriatum ventral region1.02
0.74
CklfTHThalamus2.52
2.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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