AutismKB 2.0

Annotation Detail for ZNF639


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Basic Information Top
Gene Symbol:ZNF639 ( 6230400O18Rik,ANC-2H01,ANC_2H01,ZASC1 )
Gene Full Name: zinc finger protein 639
Band: 3q26.33
Quick LinksEntrez ID:51193; OMIM: NA; Uniprot ID:ZN639_HUMAN; ENSEMBL ID: ENSG00000121864; HGNC ID: 30950
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor9 / 13630266
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal86 / 336030725
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain13 / 110098911
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye9 / 21105442
heart2 / 8962622
intestine11 / 23447246
kidney5 / 21177723
larynx1 / 2414541
liver3 / 20774314
lung12 / 33697435
lymph0 / 442700 
lymph node6 / 9161065
mammary gland3 / 15327119
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary8 / 10205178
pancreas7 / 21481232
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta4 / 28082514
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218413_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.9
Adipocyte9.75
AdrenalCortex17.45
Adrenalgland9.35
Amygdala9.55
Appendix11.1
AtrioventricularNode23.5
BDCA4+_DentriticCells9.45
Bonemarrow13.05
BronchialEpithelialCells9.2
CD105+_Endothelial9.75
CD14+_Monocytes12.05
CD19+_BCells(neg._sel.)22.45
CD33+_Myeloid11.9
CD34+11.6
CD4+_Tcells10.25
CD56+_NKCells11.15
CD71+_EarlyErythroid10.2
CD8+_Tcells9.45
CardiacMyocytes18.5
Caudatenucleus9.05
Cerebellum8.25
CerebellumPeduncles12.7
CiliaryGanglion28.8
CingulateCortex13.95
Colorectaladenocarcinoma9.75
DorsalRootGanglion20.05
FetalThyroid11.05
Fetalbrain12.8
Fetalliver9.35
Fetallung7.15
GlobusPallidus11.3
Heart15.85
Hypothalamus9.65
Kidney9.55
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-608.7
Leukemialymphoblastic(MOLT-4)8.45
Liver13.8
Lung10.5
Lymphnode8.3
Lymphoma_burkitts(Daudi)13.9
Lymphoma_burkitts(Raji)15.85
MedullaOblongata8.5
OccipitalLobe9.4
OlfactoryBulb7.85
Ovary12.6
Pancreas8.75
PancreaticIslet11.95
ParietalLobe11.35
Pituitary12.25
Placenta9.65
Pons10.85
PrefrontalCortex10.8
Prostate10.85
Salivarygland8.8
SkeletalMuscle21.8
Skin15.5
SmoothMuscle11.25
Spinalcord10.4
SubthalamicNucleus10.95
SuperiorCervicalGanglion34.8
TemporalLobe9.5
Testis8.25
TestisGermCell7.6
TestisIntersitial10.15
TestisLeydigCell17.05
TestisSeminiferousTubule26.2
Thalamus10.95
Thymus7.3
Thyroid12.2
Tongue14.65
Tonsil12.05
Trachea7.95
TrigeminalGanglion18.3
Uterus7.95
UterusCorpus12.55
WholeBlood10.65
Wholebrain7.15
colon9.5
pineal_day11.9
pineal_night11.66
retina11.8
small_intestine8.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1888_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.86 ± 0.33
Basal Forebrain6.74 ± 0.26
Basal Part of Pons6.67 ± 0.22
Cerebellar Cortex7.07 ± 0.2
Cerebellar Nuclei6.76 ± 0.27
Claustrum6.83 ± 0.3
Epithalamus6.74 ± 0.28
Frontal Lobe6.78 ± 0.3
Globus Pallidus6.81 ± 0.24
Hypothalamus6.77 ± 0.43
Insula6.89 ± 0.28
Limbic Lobe6.93 ± 0.29
Mesencephalon6.74 ± 0.29
Myelencephalon6.79 ± 0.36
Occipital Lobe7.09 ± 0.28
Parietal Lobe6.88 ± 0.31
Pontine Tegmentum6.91 ± 0.39
Striatum6.59 ± 0.38
Subthalamus6.94 ± 0.02
Temporal Lobe6.79 ± 0.3
Thalamus6.8 ± 0.3
White Matter7.33 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp639CBCerebellum18.67
20.05
Zfp639CTXCerebral cortex39.67
26.8
Zfp639HIPHippocampal region22.8
21.75
Zfp639HPFHippocampal formation27.65
23.59
Zfp639HYHypothalamus21.58
15.63
Zfp639LSXLateral septal complex19.76
13.21
Zfp639MBMidbrain22.55
18.53
Zfp639MYMedulla25.8
24.5
Zfp639OLFOlfactory bulb34.04
25.55
Zfp639PPons25.52
23.9
Zfp639PALPallidum17.7
14.18
Zfp639RHPRetrohippocampal region36.7
26.82
Zfp639sAMYStriatum-like amygdalar nuclei24.77
16.77
Zfp639STRStriatum18.57
12.49
Zfp639STRdStriatum dorsal region17.81
12.19
Zfp639STRvStriatum ventral region18.94
11.96
Zfp639THThalamus28.84
22.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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