AutismKB 2.0

Annotation Detail for CPA4


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Basic Information Top
Gene Symbol:CPA4 ( CPA3 )
Gene Full Name: carboxypeptidase A4
Band: 7q32.2
Quick LinksEntrez ID:51200; OMIM: 607635; Uniprot ID:CBPA4_HUMAN; ENSEMBL ID: ENSG00000128510; HGNC ID: 15740
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile6 / 55556107
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor27 / 263845102
glioma2 / 10688318
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal139 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites12 / 40015299
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain52 / 110098947
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye3 / 21105414
heart2 / 8962622
intestine0 / 2344720 
kidney68 / 211777321
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth11 / 67052164
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P19754
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.13 ± 1
Basal Forebrain1.71 ± 0.18
Basal Part of Pons1.34 ± 0.34
Cerebellar Cortex1.5 ± 0.65
Cerebellar Nuclei2.06 ± 0.83
Claustrum2.57 ± 0.86
Epithalamus1.45 ± 0.75
Frontal Lobe1.54 ± 0.62
Globus Pallidus2.24 ± 0.23
Hypothalamus1.75 ± 0.63
Insula1.63 ± 0.54
Limbic Lobe1.67 ± 0.56
Mesencephalon1.89 ± 0.68
Myelencephalon1.73 ± 0.64
Occipital Lobe1.8 ± 0.57
Parietal Lobe1.67 ± 0.63
Pontine Tegmentum1.78 ± 0.67
Striatum1.93 ± 0.55
Subthalamus1.89 ± 0.65
Temporal Lobe1.66 ± 0.7
Thalamus1.7 ± 0.57
White Matter2.11 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cpa4CBCerebellum1.02
1.42
Cpa4CTXCerebral cortex1.76
1.42
Cpa4HIPHippocampal region0.38
0.53
Cpa4HPFHippocampal formation0.55
0.48
Cpa4HYHypothalamus0.56
0.33
Cpa4LSXLateral septal complex0.35
0.46
Cpa4MBMidbrain1.11
1.03
Cpa4MYMedulla1.82
1.14
Cpa4OLFOlfactory bulb2.63
2.51
Cpa4PPons1.27
0.87
Cpa4PALPallidum0.12
0.07
Cpa4RHPRetrohippocampal region0.89
0.42
Cpa4sAMYStriatum-like amygdalar nuclei0.85
0.31
Cpa4STRStriatum0.39
0.3
Cpa4STRdStriatum dorsal region0.38
0.35
Cpa4STRvStriatum ventral region0.12
0.09
Cpa4THThalamus0.41
0.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CBPA4_HUMAN_215 22 215 236 MDIFLLPVANPDGYVYTQTQNR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018