AutismKB 2.0

Annotation Detail for PCP4


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Basic Information Top
Gene Symbol:PCP4 ( PEP-19 )
Gene Full Name: Purkinje cell protein 4
Band: 21q22.2
Quick LinksEntrez ID:5121; OMIM: 601629; Uniprot ID:PCP4_HUMAN; ENSEMBL ID: ENSG00000183036; HGNC ID: 8742
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal67 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye24 / 211054113
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas14 / 21481265
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate13 / 18934568
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205549_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.95
Adipocyte18.05
AdrenalCortex76.8
Adrenalgland115.85
Amygdala228.1
Appendix39.2
AtrioventricularNode12.05
BDCA4+_DentriticCells12.75
Bonemarrow19.15
BronchialEpithelialCells12.95
CD105+_Endothelial13.6
CD14+_Monocytes12
CD19+_BCells(neg._sel.)10.9
CD33+_Myeloid16.15
CD34+14
CD4+_Tcells17.2
CD56+_NKCells16.05
CD71+_EarlyErythroid16.95
CD8+_Tcells11.95
CardiacMyocytes42.45
Caudatenucleus3583.1
Cerebellum392.4
CerebellumPeduncles423.15
CiliaryGanglion97.35
CingulateCortex1040
Colorectaladenocarcinoma17.8
DorsalRootGanglion32.4
FetalThyroid115.45
Fetalbrain111.3
Fetalliver16.95
Fetallung10.35
GlobusPallidus118.5
Heart29.95
Hypothalamus1901.05
Kidney62.2
Leukemia_chronicMyelogenousK-56211.75
Leukemia_promyelocytic-HL-6011.8
Leukemialymphoblastic(MOLT-4)10.55
Liver23.75
Lung11.05
Lymphnode13.75
Lymphoma_burkitts(Daudi)22.45
Lymphoma_burkitts(Raji)27.2
MedullaOblongata948.05
OccipitalLobe218.65
OlfactoryBulb10.75
Ovary11.3
Pancreas12.1
PancreaticIslet175.5
ParietalLobe220.7
Pituitary24
Placenta12.2
Pons1007.1
PrefrontalCortex164.7
Prostate424.8
Salivarygland13.65
SkeletalMuscle32.75
Skin28.5
SmoothMuscle14.1
Spinalcord99.65
SubthalamicNucleus241.2
SuperiorCervicalGanglion49.8
TemporalLobe243.4
Testis16.45
TestisGermCell179.25
TestisIntersitial16.45
TestisLeydigCell81.1
TestisSeminiferousTubule16.25
Thalamus8560.6
Thymus9.9
Thyroid428.95
Tongue32.25
Tonsil16.85
Trachea17.15
TrigeminalGanglion30.55
Uterus156.3
UterusCorpus260.05
WholeBlood18.9
Wholebrain263
colon112
pineal_day39.04
pineal_night37.3
retina2051.025
small_intestine27.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1880_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.17 ± 1.05
Basal Forebrain11.86 ± 0.71
Basal Part of Pons11.99 ± 0.28
Cerebellar Cortex10.9 ± 0.43
Cerebellar Nuclei12.5 ± 0.56
Claustrum10.5 ± 0.46
Epithalamus11.31 ± 1.03
Frontal Lobe11.34 ± 1.06
Globus Pallidus12.31 ± 0.58
Hypothalamus10.66 ± 0.87
Insula10.52 ± 0.44
Limbic Lobe10.37 ± 0.91
Mesencephalon10.78 ± 1.08
Myelencephalon11.23 ± 1.35
Occipital Lobe12 ± 1.57
Parietal Lobe11.09 ± 0.78
Pontine Tegmentum11.31 ± 1.27
Striatum14.39 ± 1.21
Subthalamus9.1 ± 0.71
Temporal Lobe10.49 ± 0.56
Thalamus12.98 ± 1
White Matter8.91 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pcp4CBCerebellum54.47
100
Pcp4CTXCerebral cortex95.42
100
Pcp4HIPHippocampal region72.11
93.76
Pcp4HPFHippocampal formation73.51
97.47
Pcp4HYHypothalamus77.1
88.19
Pcp4LSXLateral septal complex88.47
100
Pcp4MBMidbrain71.6
88.04
Pcp4MYMedulla50.49
80.87
Pcp4OLFOlfactory bulb100
100
Pcp4PPons58.03
91.29
Pcp4PALPallidum75.61
96.32
Pcp4RHPRetrohippocampal region75.33
100
Pcp4sAMYStriatum-like amygdalar nuclei78.09
83.21
Pcp4STRStriatum100
100
Pcp4STRdStriatum dorsal region100
100
Pcp4STRvStriatum ventral region100
100
Pcp4THThalamus98.49
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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