AutismKB 2.0

Annotation Detail for TMEM85


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Basic Information Top
Gene Symbol:TMEM85 ( FLJ90746,MGC24415,PIG17 )
Gene Full Name: transmembrane protein 85
Band: 15q14
Quick LinksEntrez ID:51234; OMIM: NA; Uniprot ID:TMM85_HUMAN; ENSEMBL ID: ENSG00000128463; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst4 / 6231964
fetus47 / 56401283
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult204 / 1939121105
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor1 / 3436629
chondrosarcoma26 / 82823313
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor14 / 119369117
germ cell tumor13 / 26384549
glioma13 / 106883121
head and neck tumor8 / 13630258
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor14 / 96359145
lung tumor5 / 10312748
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal321 / 336030795
ovarian tumor10 / 76682130
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites8 / 40015199
bladder0 / 297570 
blood6 / 12347848
bone18 / 71655251
bone marrow4 / 4880181
brain79 / 110098971
cervix9 / 48171186
connective tissue23 / 149255154
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus2 / 2020998
eye17 / 21105480
heart5 / 8962655
intestine16 / 23447268
kidney6 / 21177728
larynx1 / 2414541
liver25 / 207743120
lung40 / 336974118
lymph3 / 4427067
lymph node10 / 91610109
mammary gland16 / 153271104
mouth7 / 67052104
muscle8 / 10771574
nerve1 / 1576863
ovary10 / 10205197
pancreas53 / 214812246
parathyroid8 / 20539389
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta46 / 280825163
prostate11 / 18934558
salivary gland0 / 201550 
skin28 / 210574132
spleen1 / 5395218
stomach12 / 96619124
testis18 / 33044254
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P106481
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.54 ± 0.64
Basal Forebrain8.93 ± 0.3
Basal Part of Pons9.47 ± 0.3
Cerebellar Cortex9.16 ± 0.34
Cerebellar Nuclei9.39 ± 0.37
Claustrum8.35 ± 0.74
Epithalamus9.22 ± 0.29
Frontal Lobe9.3 ± 0.34
Globus Pallidus8.74 ± 0.4
Hypothalamus9.49 ± 0.26
Insula9.21 ± 0.28
Limbic Lobe8.74 ± 0.66
Mesencephalon8.93 ± 0.5
Myelencephalon8.96 ± 0.58
Occipital Lobe8.45 ± 0.66
Parietal Lobe9.06 ± 0.5
Pontine Tegmentum9.04 ± 0.49
Striatum8.43 ± 0.46
Subthalamus9.43 ± 0.42
Temporal Lobe9.18 ± 0.44
Thalamus9.03 ± 0.4
White Matter9.11 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem85CBCerebellum62.14
100
Tmem85CTXCerebral cortex100
100
Tmem85HIPHippocampal region100
100
Tmem85HPFHippocampal formation100
100
Tmem85HYHypothalamus90.28
95.16
Tmem85LSXLateral septal complex100
100
Tmem85MBMidbrain96.35
100
Tmem85MYMedulla77.8
100
Tmem85OLFOlfactory bulb100
100
Tmem85PPons78.9
100
Tmem85PALPallidum89.56
100
Tmem85RHPRetrohippocampal region100
100
Tmem85sAMYStriatum-like amygdalar nuclei100
100
Tmem85STRStriatum100
100
Tmem85STRdStriatum dorsal region100
100
Tmem85STRvStriatum ventral region100
100
Tmem85THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001317 23 151 173 CQSMGLLPTHASDWLAFIEPPER Peptide Atlas
TMM85_HUMAN_2 10 2 11 TAQGGLVANR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018