AutismKB 2.0

Annotation Detail for NT5C3


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Basic Information Top
Gene Symbol:NT5C3 ( MGC27337,MGC87109,MGC87828,P5'N-1,PN-I,PSN1,UMPH,UMPH1,cN-III )
Gene Full Name: 5'-nucleotidase, cytosolic III
Band: 7p14.3
Quick LinksEntrez ID:51251; OMIM: 606224; Uniprot ID:5NT3_HUMAN; ENSEMBL ID: ENSG00000122643; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor6 / 34366174
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma4 / 7175555
non-neoplasia7 / 9725071
normal111 / 336030733
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood8 / 12347864
bone2 / 7165527
bone marrow0 / 488010 
brain22 / 110098919
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye5 / 21105423
heart4 / 8962644
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver7 / 20774333
lung11 / 33697432
lymph0 / 442700 
lymph node11 / 91610120
mammary gland1 / 1532716
mouth2 / 6705229
muscle15 / 107715139
nerve0 / 157680 
ovary4 / 10205139
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland1 / 2015549
skin4 / 21057418
spleen3 / 5395255
stomach3 / 9661931
testis9 / 33044227
thymus6 / 8113173
thyroid1 / 4747321
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7714_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.42 ± 0.2
Basal Forebrain7.19 ± 0.21
Basal Part of Pons7.23 ± 0.12
Cerebellar Cortex7.58 ± 0.19
Cerebellar Nuclei7.17 ± 0.15
Claustrum7.02 ± 0.37
Epithalamus7.55 ± 0.18
Frontal Lobe7.39 ± 0.25
Globus Pallidus7.06 ± 0.14
Hypothalamus7.46 ± 0.22
Insula7.37 ± 0.32
Limbic Lobe7.32 ± 0.3
Mesencephalon7.26 ± 0.3
Myelencephalon7.3 ± 0.3
Occipital Lobe7.22 ± 0.23
Parietal Lobe7.3 ± 0.23
Pontine Tegmentum7.38 ± 0.26
Striatum7.19 ± 0.25
Subthalamus7.37 ± 0.26
Temporal Lobe7.41 ± 0.26
Thalamus7.3 ± 0.22
White Matter7.42 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nt5c3CBCerebellum46.93
84.07
Nt5c3CTXCerebral cortex100
100
Nt5c3HIPHippocampal region76.32
100
Nt5c3HPFHippocampal formation72.32
100
Nt5c3HYHypothalamus81.1
73.25
Nt5c3LSXLateral septal complex76.57
65.73
Nt5c3MBMidbrain84.12
86.01
Nt5c3MYMedulla66.79
82.66
Nt5c3OLFOlfactory bulb78.79
74.64
Nt5c3PPons63.07
76.69
Nt5c3PALPallidum74.63
72.61
Nt5c3RHPRetrohippocampal region65.83
62.36
Nt5c3sAMYStriatum-like amygdalar nuclei75.1
60.08
Nt5c3STRStriatum67.4
52.66
Nt5c3STRdStriatum dorsal region62.73
49.09
Nt5c3STRvStriatum ventral region74.53
53.85
Nt5c3THThalamus91.92
89.69
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00032784 12 103 114 CPTCHNIIDNCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018