AutismKB 2.0

Annotation Detail for MARCH2


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Basic Information Top
Gene Symbol:MARCH2 ( MARCH-II,RNF172 )
Gene Full Name: membrane-associated ring finger (C3HC4) 2
Band: 19p13.2
Quick LinksEntrez ID:51257; OMIM: 613332; Uniprot ID:MARH2_HUMAN; ENSEMBL ID: ENSG00000099785; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal40 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow1 / 4880120
brain14 / 110098912
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine3 / 23447212
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph3 / 4427067
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta3 / 28082510
prostate5 / 18934526
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210075_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.8
Adipocyte11.45
AdrenalCortex9.9
Adrenalgland8.2
Amygdala12.1
Appendix9.7
AtrioventricularNode7.15
BDCA4+_DentriticCells66.35
Bonemarrow25.95
BronchialEpithelialCells9.1
CD105+_Endothelial9.95
CD14+_Monocytes37.25
CD19+_BCells(neg._sel.)10.75
CD33+_Myeloid12.95
CD34+11.95
CD4+_Tcells11
CD56+_NKCells12
CD71+_EarlyErythroid125.95
CD8+_Tcells8.8
CardiacMyocytes12.1
Caudatenucleus12.95
Cerebellum8
CerebellumPeduncles11.05
CiliaryGanglion6.65
CingulateCortex18.1
Colorectaladenocarcinoma9.2
DorsalRootGanglion7.3
FetalThyroid13.75
Fetalbrain10
Fetalliver20.9
Fetallung8.7
GlobusPallidus7.2
Heart39.3
Hypothalamus15.15
Kidney7.75
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)6.95
Liver23.85
Lung48.75
Lymphnode8.6
Lymphoma_burkitts(Daudi)11.55
Lymphoma_burkitts(Raji)12.4
MedullaOblongata12.15
OccipitalLobe10.85
OlfactoryBulb7.8
Ovary6.2
Pancreas7.55
PancreaticIslet10.45
ParietalLobe15.55
Pituitary11.45
Placenta9.55
Pons9.3
PrefrontalCortex18.15
Prostate14.3
Salivarygland6.5
SkeletalMuscle10.9
Skin7.25
SmoothMuscle11.3
Spinalcord17.75
SubthalamicNucleus21.85
SuperiorCervicalGanglion10.8
TemporalLobe12.7
Testis8.7
TestisGermCell8.1
TestisIntersitial7.35
TestisLeydigCell9.65
TestisSeminiferousTubule8.45
Thalamus35.25
Thymus9.25
Thyroid15.7
Tongue9.4
Tonsil9.55
Trachea7.5
TrigeminalGanglion9.45
Uterus8.2
UterusCorpus8.7
WholeBlood59.15
Wholebrain27.35
colon9.95
pineal_day14.22
pineal_night12.8
retina12.625
small_intestine9.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P33683
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.3 ± 0.35
Basal Forebrain5.36 ± 0.35
Basal Part of Pons5.82 ± 0.34
Cerebellar Cortex4.98 ± 0.35
Cerebellar Nuclei5.8 ± 0.37
Claustrum4.96 ± 0.63
Epithalamus5.28 ± 0.53
Frontal Lobe5.54 ± 0.48
Globus Pallidus5.86 ± 0.37
Hypothalamus5.33 ± 0.57
Insula5.2 ± 0.41
Limbic Lobe5.19 ± 0.49
Mesencephalon5.43 ± 0.54
Myelencephalon5.44 ± 0.49
Occipital Lobe5.37 ± 0.39
Parietal Lobe5.57 ± 0.41
Pontine Tegmentum5.41 ± 0.42
Striatum5.52 ± 0.38
Subthalamus5.76 ± 0.44
Temporal Lobe5.46 ± 0.39
Thalamus5.6 ± 0.48
White Matter5.14 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
March2CBCerebellum23.46
44.96
March2CTXCerebral cortex16.95
14.34
March2HIPHippocampal region20.85
24.01
March2HPFHippocampal formation22.5
23.36
March2HYHypothalamus8.42
8.47
March2LSXLateral septal complex0.03
0
March2MBMidbrain12.58
16.71
March2MYMedulla52.87
80.93
March2OLFOlfactory bulb20.09
17.73
March2PPons34.2
53
March2PALPallidum13.8
18.96
March2RHPRetrohippocampal region26.76
23.61
March2sAMYStriatum-like amygdalar nuclei15.29
12.77
March2STRStriatum7.67
6.46
March2STRdStriatum dorsal region6.3
5.07
March2STRvStriatum ventral region12.1
10.06
March2THThalamus23.08
25.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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