AutismKB 2.0

Annotation Detail for BFAR


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Basic Information Top
Gene Symbol:BFAR ( BAR,RNF47 )
Gene Full Name: bifunctional apoptosis regulator
Band: 16p13.12
Quick LinksEntrez ID:51283; OMIM: NA; Uniprot ID:BFAR_HUMAN; ENSEMBL ID: ENSG00000103429; HGNC ID: 17613
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst9 / 62319144
fetus31 / 56401254
neonate2 / 3109764
infant1 / 2362042
juvenile6 / 55556107
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor25 / 26384594
glioma8 / 10688374
head and neck tumor8 / 13630258
kidney tumor7 / 68959101
leukemia6 / 9584262
liver tumor8 / 9635983
lung tumor7 / 10312767
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal167 / 336030749
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer4 / 10268038
retinoblastoma7 / 46356151
skin tumor23 / 124949184
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone4 / 7165555
bone marrow2 / 4880140
brain50 / 110098945
cervix2 / 4817141
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye15 / 21105471
heart4 / 8962644
intestine14 / 23447259
kidney17 / 21177780
larynx1 / 2414541
liver14 / 20774367
lung17 / 33697450
lymph1 / 4427022
lymph node4 / 9161043
mammary gland8 / 15327152
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary2 / 10205119
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate6 / 18934531
salivary gland1 / 2015549
skin29 / 210574137
spleen2 / 5395237
stomach6 / 9661962
testis20 / 33044260
thymus0 / 811310 
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218056_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.25
Adipocyte12.9
AdrenalCortex10.35
Adrenalgland7.6
Amygdala8.6
Appendix9.4
AtrioventricularNode8.3
BDCA4+_DentriticCells19.75
Bonemarrow9.35
BronchialEpithelialCells21
CD105+_Endothelial13.45
CD14+_Monocytes12.75
CD19+_BCells(neg._sel.)26.55
CD33+_Myeloid21.85
CD34+26.6
CD4+_Tcells26.1
CD56+_NKCells39.95
CD71+_EarlyErythroid7.95
CD8+_Tcells44.1
CardiacMyocytes28.4
Caudatenucleus7.25
Cerebellum7.2
CerebellumPeduncles10.4
CiliaryGanglion7.95
CingulateCortex9.05
Colorectaladenocarcinoma13.2
DorsalRootGanglion11.55
FetalThyroid8.5
Fetalbrain10.05
Fetalliver7.3
Fetallung8.1
GlobusPallidus6.75
Heart11.95
Hypothalamus8.9
Kidney7.2
Leukemia_chronicMyelogenousK-56212.25
Leukemia_promyelocytic-HL-607.8
Leukemialymphoblastic(MOLT-4)10
Liver11.25
Lung12.45
Lymphnode8.9
Lymphoma_burkitts(Daudi)12.85
Lymphoma_burkitts(Raji)13.5
MedullaOblongata7.4
OccipitalLobe7.25
OlfactoryBulb9.5
Ovary6.1
Pancreas9.65
PancreaticIslet23.75
ParietalLobe9.15
Pituitary10.75
Placenta11.05
Pons8.5
PrefrontalCortex10.7
Prostate8.95
Salivarygland6.95
SkeletalMuscle14.75
Skin7.3
SmoothMuscle37.75
Spinalcord8.4
SubthalamicNucleus8.3
SuperiorCervicalGanglion11.55
TemporalLobe7.8
Testis6.8
TestisGermCell7.6
TestisIntersitial7.25
TestisLeydigCell8.25
TestisSeminiferousTubule8.55
Thalamus8.7
Thymus9.65
Thyroid10.65
Tongue9.7
Tonsil8.55
Trachea7.1
TrigeminalGanglion11
Uterus8.85
UterusCorpus8.75
WholeBlood9.25
Wholebrain7.95
colon7.65
pineal_day20.1
pineal_night21.88
retina27.6
small_intestine7.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P184931
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.69
Basal Forebrain4.4 ± 0.18
Basal Part of Pons4.64 ± 0.26
Cerebellar Cortex4.52 ± 0.32
Cerebellar Nuclei4.15 ± 0.37
Claustrum4.48 ± 0.66
Epithalamus4.38 ± 0.35
Frontal Lobe4.49 ± 0.39
Globus Pallidus4.65 ± 0.34
Hypothalamus4.47 ± 0.37
Insula4.26 ± 0.37
Limbic Lobe4.47 ± 0.39
Mesencephalon4.38 ± 0.49
Myelencephalon4.41 ± 0.43
Occipital Lobe4.37 ± 0.4
Parietal Lobe4.49 ± 0.45
Pontine Tegmentum4.52 ± 0.48
Striatum4.53 ± 0.38
Subthalamus4.54 ± 0.03
Temporal Lobe4.39 ± 0.43
Thalamus4.63 ± 0.37
White Matter5.07 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BfarCBCerebellum16.26
21.7
BfarCTXCerebral cortex10.82
7.66
BfarHIPHippocampal region16.01
15.05
BfarHPFHippocampal formation16.35
14.35
BfarHYHypothalamus1.87
2.08
BfarLSXLateral septal complex0.08
0.09
BfarMBMidbrain2.4
2.76
BfarMYMedulla7.49
9.4
BfarOLFOlfactory bulb12.56
9.34
BfarPPons8.17
10.75
BfarPALPallidum4.41
4.42
BfarRHPRetrohippocampal region17.99
14.14
BfarsAMYStriatum-like amygdalar nuclei5.77
4.15
BfarSTRStriatum3.8
3
BfarSTRdStriatum dorsal region3.7
3.11
BfarSTRvStriatum ventral region6.63
4.67
BfarTHThalamus4.45
4.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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