AutismKB 2.0

Annotation Detail for RASL12


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Basic Information Top
Gene Symbol:RASL12 ( RIS )
Gene Full Name: RAS-like, family 12
Band: 15q22.31
Quick LinksEntrez ID:51285; OMIM: NA; Uniprot ID:RASLC_HUMAN; ENSEMBL ID: ENSG00000103710; HGNC ID: 30289
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal73 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver4 / 20774319
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate17 / 18934589
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219167_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.3
Adipocyte6.15
AdrenalCortex6.4
Adrenalgland5.25
Amygdala6.75
Appendix6.65
AtrioventricularNode4.95
BDCA4+_DentriticCells6.95
Bonemarrow6.05
BronchialEpithelialCells6.15
CD105+_Endothelial6.3
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid8
CD34+7.8
CD4+_Tcells6.8
CD56+_NKCells7.3
CD71+_EarlyErythroid5.85
CD8+_Tcells5.95
CardiacMyocytes8.05
Caudatenucleus6.45
Cerebellum5.5
CerebellumPeduncles9.1
CiliaryGanglion14.1
CingulateCortex6.7
Colorectaladenocarcinoma6.3
DorsalRootGanglion11.15
FetalThyroid6.1
Fetalbrain6
Fetalliver5.25
Fetallung37.45
GlobusPallidus4.55
Heart19.3
Hypothalamus25.05
Kidney5.05
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)5.05
Liver8.2
Lung41.5
Lymphnode7.15
Lymphoma_burkitts(Daudi)7.8
Lymphoma_burkitts(Raji)8.65
MedullaOblongata5.8
OccipitalLobe6.3
OlfactoryBulb10.6
Ovary8.45
Pancreas5
PancreaticIslet6.7
ParietalLobe7.2
Pituitary7.85
Placenta7.05
Pons5.95
PrefrontalCortex8.95
Prostate17.65
Salivarygland5
SkeletalMuscle7.35
Skin5.2
SmoothMuscle7.1
Spinalcord31.7
SubthalamicNucleus7.65
SuperiorCervicalGanglion7.3
TemporalLobe6.5
Testis13.4
TestisGermCell27.45
TestisIntersitial8.3
TestisLeydigCell7.9
TestisSeminiferousTubule10.85
Thalamus20.6
Thymus5
Thyroid7.8
Tongue9
Tonsil6.1
Trachea8.8
TrigeminalGanglion6.55
Uterus50.45
UterusCorpus13.2
WholeBlood6.85
Wholebrain5.35
colon6.85
pineal_day8.02
pineal_night7.68
retina37.175
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P48868
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.95 ± 0.71
Basal Forebrain3.94 ± 0.58
Basal Part of Pons3.87 ± 0.63
Cerebellar Cortex4.15 ± 0.65
Cerebellar Nuclei3.77 ± 0.91
Claustrum4.29 ± 0.91
Epithalamus3.59 ± 0.56
Frontal Lobe3.85 ± 0.68
Globus Pallidus4.33 ± 0.96
Hypothalamus3.33 ± 0.41
Insula3.84 ± 0.44
Limbic Lobe3.99 ± 0.67
Mesencephalon3.86 ± 0.74
Myelencephalon3.96 ± 0.73
Occipital Lobe3.86 ± 0.81
Parietal Lobe3.82 ± 0.74
Pontine Tegmentum3.81 ± 0.66
Striatum3.75 ± 0.76
Subthalamus3.6 ± 1.2
Temporal Lobe3.81 ± 0.74
Thalamus4.06 ± 0.63
White Matter4.3 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rasl12CBCerebellum1.55
2.12
Rasl12CTXCerebral cortex1.02
0.99
Rasl12HIPHippocampal region1.64
1.59
Rasl12HPFHippocampal formation1.36
1.32
Rasl12HYHypothalamus0.04
0.13
Rasl12LSXLateral septal complex0.15
0.19
Rasl12MBMidbrain0.17
0.27
Rasl12MYMedulla0.98
1.4
Rasl12OLFOlfactory bulb1.67
2.09
Rasl12PPons0.3
0.4
Rasl12PALPallidum0.18
0.27
Rasl12RHPRetrohippocampal region0.89
0.89
Rasl12sAMYStriatum-like amygdalar nuclei0.11
0.11
Rasl12STRStriatum1.3
1.62
Rasl12STRdStriatum dorsal region2.08
2.64
Rasl12STRvStriatum ventral region0.07
0.09
Rasl12THThalamus0.28
0.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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