AutismKB 2.0

Annotation Detail for SLC15A3


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Basic Information Top
Gene Symbol:SLC15A3 ( FLJ26631,OCTP,PHT2,PTR3 )
Gene Full Name: solute carrier family 15, member 3
Band: 11q12.2
Quick LinksEntrez ID:51296; OMIM: 610408; Uniprot ID:S15A3_HUMAN; ENSEMBL ID: ENSG00000110446; HGNC ID: 18068
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal42 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate0 / 1893450 
salivary gland1 / 2015549
skin2 / 2105749
spleen3 / 5395255
stomach1 / 9661910
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219593_at
Cell line Expression level Expression bar
721_B_lymphoblasts20
Adipocyte4
AdrenalCortex4.1
Adrenalgland3.4
Amygdala4.25
Appendix4.05
AtrioventricularNode3.15
BDCA4+_DentriticCells210.8
Bonemarrow3.95
BronchialEpithelialCells4.05
CD105+_Endothelial4.75
CD14+_Monocytes297.8
CD19+_BCells(neg._sel.)84.3
CD33+_Myeloid277.15
CD34+5.15
CD4+_Tcells4.3
CD56+_NKCells5.3
CD71+_EarlyErythroid3.75
CD8+_Tcells3.95
CardiacMyocytes4.95
Caudatenucleus3.65
Cerebellum3.3
CerebellumPeduncles4.55
CiliaryGanglion4.45
CingulateCortex4.85
Colorectaladenocarcinoma3.95
DorsalRootGanglion5.85
FetalThyroid3.95
Fetalbrain4.1
Fetalliver3.45
Fetallung4.15
GlobusPallidus2.95
Heart18.2
Hypothalamus4.7
Kidney3.25
Leukemia_chronicMyelogenousK-5623.6
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.35
Liver5.4
Lung299.05
Lymphnode30.75
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)5.6
MedullaOblongata3.8
OccipitalLobe3.65
OlfactoryBulb10.7
Ovary2.7
Pancreas3.85
PancreaticIslet4.3
ParietalLobe4.25
Pituitary4.75
Placenta28.6
Pons3.9
PrefrontalCortex5.15
Prostate4.55
Salivarygland3.2
SkeletalMuscle4.55
Skin3
SmoothMuscle5.9
Spinalcord6.15
SubthalamicNucleus3.7
SuperiorCervicalGanglion4.45
TemporalLobe3.7
Testis3.5
TestisGermCell3.4
TestisIntersitial3.35
TestisLeydigCell4
TestisSeminiferousTubule3.45
Thalamus4.15
Thymus7.65
Thyroid5.15
Tongue3.9
Tonsil4.95
Trachea3.4
TrigeminalGanglion4.05
Uterus3.35
UterusCorpus3.6
WholeBlood266.05
Wholebrain3.45
colon4.05
pineal_day5
pineal_night4.84
retina6.15
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75786
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.37 ± 0.59
Basal Forebrain4.57 ± 0.35
Basal Part of Pons4.61 ± 0.41
Cerebellar Cortex4.03 ± 0.38
Cerebellar Nuclei5.11 ± 0.37
Claustrum3.79 ± 0.58
Epithalamus5.88 ± 0.57
Frontal Lobe4.29 ± 0.61
Globus Pallidus5.82 ± 0.34
Hypothalamus4.64 ± 0.88
Insula4.51 ± 0.4
Limbic Lobe4.13 ± 0.71
Mesencephalon4.63 ± 0.59
Myelencephalon4.77 ± 0.61
Occipital Lobe4.67 ± 0.65
Parietal Lobe4.38 ± 0.6
Pontine Tegmentum4.5 ± 0.71
Striatum5.48 ± 0.49
Subthalamus4.41 ± 0.28
Temporal Lobe4.8 ± 0.5
Thalamus4.86 ± 0.48
White Matter4.29 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc15a3CBCerebellum3.5
3.47
Slc15a3CTXCerebral cortex1.03
0.87
Slc15a3HIPHippocampal region1.1
1.09
Slc15a3HPFHippocampal formation0.82
0.8
Slc15a3HYHypothalamus0.23
0.18
Slc15a3LSXLateral septal complex0.36
0.21
Slc15a3MBMidbrain0.55
0.96
Slc15a3MYMedulla2.28
2.37
Slc15a3OLFOlfactory bulb3.9
2.81
Slc15a3PPons1.07
1.38
Slc15a3PALPallidum0.36
0.24
Slc15a3RHPRetrohippocampal region0.38
0.4
Slc15a3sAMYStriatum-like amygdalar nuclei0.33
0.27
Slc15a3STRStriatum0.29
0.19
Slc15a3STRdStriatum dorsal region0.08
0.05
Slc15a3STRvStriatum ventral region0.89
0.5
Slc15a3THThalamus0.76
0.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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