AutismKB 2.0

Annotation Detail for CYP39A1


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Basic Information Top
Gene Symbol:CYP39A1 ( - )
Gene Full Name: cytochrome P450, family 39, subfamily A, polypeptide 1
Band: 6p12.3
Quick LinksEntrez ID:51302; OMIM: 605994; Uniprot ID:CP39A_HUMAN; ENSEMBL ID: ENSG00000146233; HGNC ID: 17449
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal48 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix1 / 4817120
connective tissue22 / 149255147
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney7 / 21177733
larynx0 / 241450 
liver11 / 20774352
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220432_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.55
Adipocyte8.85
AdrenalCortex13.05
Adrenalgland8.6
Amygdala8.45
Appendix13.55
AtrioventricularNode14.7
BDCA4+_DentriticCells8.7
Bonemarrow11.1
BronchialEpithelialCells8.7
CD105+_Endothelial8.8
CD14+_Monocytes9.85
CD19+_BCells(neg._sel.)9.15
CD33+_Myeloid10.85
CD34+10.75
CD4+_Tcells9
CD56+_NKCells9.65
CD71+_EarlyErythroid8.95
CD8+_Tcells8.05
CardiacMyocytes20.95
Caudatenucleus8.2
Cerebellum7.65
CerebellumPeduncles12.1
CiliaryGanglion10.75
CingulateCortex10.3
Colorectaladenocarcinoma8.95
DorsalRootGanglion11.75
FetalThyroid10.7
Fetalbrain8.5
Fetalliver11.4
Fetallung6.5
GlobusPallidus7.75
Heart18.5
Hypothalamus9.3
Kidney9.2
Leukemia_chronicMyelogenousK-5628.15
Leukemia_promyelocytic-HL-608.15
Leukemialymphoblastic(MOLT-4)6.85
Liver16.4
Lung9.85
Lymphnode7.15
Lymphoma_burkitts(Daudi)12.25
Lymphoma_burkitts(Raji)16.15
MedullaOblongata7.9
OccipitalLobe8.05
OlfactoryBulb7.35
Ovary7.5
Pancreas7.95
PancreaticIslet10.05
ParietalLobe10.9
Pituitary10.75
Placenta8.9
Pons9.8
PrefrontalCortex10.5
Prostate11.55
Salivarygland7.9
SkeletalMuscle17.25
Skin17.9
SmoothMuscle10.25
Spinalcord9.6
SubthalamicNucleus9
SuperiorCervicalGanglion17.75
TemporalLobe8.95
Testis7.75
TestisGermCell7.05
TestisIntersitial8.1
TestisLeydigCell9.85
TestisSeminiferousTubule7.8
Thalamus9.65
Thymus6.7
Thyroid14.1
Tongue11.75
Tonsil9.2
Trachea7.55
TrigeminalGanglion17.6
Uterus7.15
UterusCorpus21.45
WholeBlood9.55
Wholebrain7.15
colon9.05
pineal_day10.92
pineal_night10.9
retina11.3
small_intestine8.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8081_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.69 ± 1.17
Basal Forebrain2.84 ± 0.73
Basal Part of Pons2.25 ± 0.61
Cerebellar Cortex3.07 ± 0.48
Cerebellar Nuclei2.61 ± 0.62
Claustrum2.83 ± 0.7
Epithalamus4.24 ± 0.58
Frontal Lobe2.55 ± 0.83
Globus Pallidus4 ± 0.58
Hypothalamus2.47 ± 0.41
Insula2.15 ± 0.79
Limbic Lobe2.46 ± 0.75
Mesencephalon2.86 ± 0.72
Myelencephalon2.67 ± 0.79
Occipital Lobe2.67 ± 0.7
Parietal Lobe2.57 ± 0.87
Pontine Tegmentum2.83 ± 0.72
Striatum2.62 ± 0.8
Subthalamus2.32 ± 0.76
Temporal Lobe2.6 ± 0.75
Thalamus2.79 ± 0.62
White Matter4.44 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyp39a1CBCerebellum1.01
1.71
Cyp39a1CTXCerebral cortex2.25
2.21
Cyp39a1HIPHippocampal region0.31
0.34
Cyp39a1HPFHippocampal formation0.99
1.38
Cyp39a1HYHypothalamus0.77
0.73
Cyp39a1LSXLateral septal complex0.21
0.16
Cyp39a1MBMidbrain1.85
2.84
Cyp39a1MYMedulla2.91
4.14
Cyp39a1OLFOlfactory bulb1.31
1.94
Cyp39a1PPons2.71
3.83
Cyp39a1PALPallidum0.37
0.37
Cyp39a1RHPRetrohippocampal region1.88
2.5
Cyp39a1sAMYStriatum-like amygdalar nuclei0.53
0.5
Cyp39a1STRStriatum0.42
0.4
Cyp39a1STRdStriatum dorsal region0.46
0.44
Cyp39a1STRvStriatum ventral region0.22
0.17
Cyp39a1THThalamus0.7
0.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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