AutismKB 2.0

Annotation Detail for SLC25A37


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Basic Information Top
Gene Symbol:SLC25A37 ( MFRN,MSC,MSCP,PRO1278,PRO1584,PRO2217 )
Gene Full Name: solute carrier family 25, member 37
Band: 8p21.2
Quick LinksEntrez ID:51312; OMIM: 610387; Uniprot ID:MFRN1_HUMAN; ENSEMBL ID: ENSG00000147454; HGNC ID: 29786
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult32 / 193912116
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus106 / 564012187
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult146 / 193912175
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal69 / 336030720
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal16 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia12 / 95842125
liver tumor8 / 9635983
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia5 / 9725051
normal292 / 336030786
ovarian tumor15 / 76682195
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone2 / 7165527
bone marrow1 / 4880120
brain12 / 110098910
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye1 / 2110544
heart7 / 8962678
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver3 / 20774314
lung7 / 33697420
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate8 / 18934542
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver5 / 20774324
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites2 / 4001549
bladder3 / 29757100
blood18 / 123478145
bone9 / 71655125
bone marrow2 / 4880140
brain32 / 110098929
cervix4 / 4817183
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye15 / 21105471
heart5 / 8962655
intestine26 / 234472110
kidney10 / 21177747
larynx1 / 2414541
liver30 / 207743144
lung39 / 336974115
lymph3 / 4427067
lymph node17 / 91610185
mammary gland10 / 15327165
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary17 / 102051166
pancreas14 / 21481265
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta15 / 28082553
prostate13 / 18934568
salivary gland1 / 2015549
skin2 / 2105749
spleen5 / 5395292
stomach1 / 9661910
testis16 / 33044248
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221920_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.3
Adipocyte7
AdrenalCortex50.45
Adrenalgland24.55
Amygdala10.6
Appendix9.8
AtrioventricularNode8
BDCA4+_DentriticCells7.45
Bonemarrow733.35
BronchialEpithelialCells8.1
CD105+_Endothelial370.1
CD14+_Monocytes12.45
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid25.75
CD34+37.5
CD4+_Tcells12.8
CD56+_NKCells7.75
CD71+_EarlyErythroid1756.5
CD8+_Tcells9.05
CardiacMyocytes11.6
Caudatenucleus8.15
Cerebellum6.25
CerebellumPeduncles11.1
CiliaryGanglion7.1
CingulateCortex8.55
Colorectaladenocarcinoma10.5
DorsalRootGanglion7.05
FetalThyroid43.75
Fetalbrain8.45
Fetalliver451.9
Fetallung133.7
GlobusPallidus6.7
Heart13.65
Hypothalamus8.25
Kidney7.5
Leukemia_chronicMyelogenousK-56234.1
Leukemia_promyelocytic-HL-6014.7
Leukemialymphoblastic(MOLT-4)10.9
Liver17.75
Lung17.5
Lymphnode6.55
Lymphoma_burkitts(Daudi)23.7
Lymphoma_burkitts(Raji)163.75
MedullaOblongata6.5
OccipitalLobe6.65
OlfactoryBulb8.45
Ovary7.25
Pancreas7.55
PancreaticIslet12
ParietalLobe9.75
Pituitary8.55
Placenta11.2
Pons8.65
PrefrontalCortex25.8
Prostate241.5
Salivarygland8.1
SkeletalMuscle13.85
Skin7.3
SmoothMuscle8.7
Spinalcord7.65
SubthalamicNucleus9.15
SuperiorCervicalGanglion11.3
TemporalLobe9.1
Testis5.85
TestisGermCell6.95
TestisIntersitial7.95
TestisLeydigCell9.5
TestisSeminiferousTubule6.45
Thalamus8.35
Thymus4.9
Thyroid13.65
Tongue9.5
Tonsil8.05
Trachea7.9
TrigeminalGanglion11.1
Uterus15.15
UterusCorpus8.7
WholeBlood361.15
Wholebrain6.95
colon10.25
pineal_day11.7
pineal_night15.86
retina12.75
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14239_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.61 ± 0.36
Basal Forebrain6.75 ± 0.2
Basal Part of Pons6.67 ± 0.29
Cerebellar Cortex6 ± 0.38
Cerebellar Nuclei6.75 ± 0.35
Claustrum6.48 ± 0.58
Epithalamus6.49 ± 0.58
Frontal Lobe6.22 ± 0.36
Globus Pallidus6.92 ± 0.2
Hypothalamus6.08 ± 0.39
Insula6.18 ± 0.41
Limbic Lobe6.43 ± 0.51
Mesencephalon6.3 ± 0.51
Myelencephalon6.43 ± 0.54
Occipital Lobe7.01 ± 0.63
Parietal Lobe6.58 ± 0.37
Pontine Tegmentum6.43 ± 0.56
Striatum7.37 ± 0.39
Subthalamus6.46 ± 0.16
Temporal Lobe6.3 ± 0.36
Thalamus6.24 ± 0.42
White Matter7.05 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc25a37CBCerebellum23.22
24.76
Slc25a37CTXCerebral cortex25.37
16.06
Slc25a37HIPHippocampal region14.47
13.31
Slc25a37HPFHippocampal formation13.52
11.34
Slc25a37HYHypothalamus3.39
2.72
Slc25a37LSXLateral septal complex1.82
1.36
Slc25a37MBMidbrain12.88
11.51
Slc25a37MYMedulla24.14
23.5
Slc25a37OLFOlfactory bulb22.59
16.81
Slc25a37PPons18.17
17.4
Slc25a37PALPallidum5.38
4.3
Slc25a37RHPRetrohippocampal region12.37
8.96
Slc25a37sAMYStriatum-like amygdalar nuclei3.39
2.61
Slc25a37STRStriatum11.99
7.56
Slc25a37STRdStriatum dorsal region14.32
8.83
Slc25a37STRvStriatum ventral region11.76
7.64
Slc25a37THThalamus44.58
39.02
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018