AutismKB 2.0

Annotation Detail for WAC


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WAC ( BM-016,MGC10753,PRO1741,Wwp4,bA48B24,bA48B24.1 )
Gene Full Name: WW domain containing adaptor with coiled-coil
Band: 10p12.1
Quick LinksEntrez ID:51322; OMIM: NA; Uniprot ID:WAC_HUMAN; ENSEMBL ID: ENSG00000095787; HGNC ID: 17327
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal76 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain8 / 11009897
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye11 / 21105452
heart2 / 8962622
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver4 / 20774319
lung4 / 33697411
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach11 / 96619113
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217742_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts254.55
Adipocyte43.75
AdrenalCortex24.15
Adrenalgland15.2
Amygdala185.1
Appendix36.9
AtrioventricularNode49.3
BDCA4+_DentriticCells270.15
Bonemarrow22.75
BronchialEpithelialCells59.55
CD105+_Endothelial162.5
CD14+_Monocytes393.65
CD19+_BCells(neg._sel.)590.3
CD33+_Myeloid281.1
CD34+274.2
CD4+_Tcells241.3
CD56+_NKCells697.55
CD71+_EarlyErythroid260
CD8+_Tcells285.35
CardiacMyocytes30.95
Caudatenucleus64.95
Cerebellum64.3
CerebellumPeduncles62.3
CiliaryGanglion19.3
CingulateCortex75.95
Colorectaladenocarcinoma75.6
DorsalRootGanglion27
FetalThyroid57.8
Fetalbrain95.2
Fetalliver67
Fetallung101.65
GlobusPallidus51.35
Heart5
Hypothalamus140
Kidney12.45
Leukemia_chronicMyelogenousK-56284.3
Leukemia_promyelocytic-HL-6073.1
Leukemialymphoblastic(MOLT-4)128
Liver6.1
Lung8.65
Lymphnode86.9
Lymphoma_burkitts(Daudi)121.45
Lymphoma_burkitts(Raji)116.65
MedullaOblongata81.25
OccipitalLobe85.45
OlfactoryBulb109.95
Ovary41.6
Pancreas54.2
PancreaticIslet72.1
ParietalLobe58.65
Pituitary102
Placenta107.05
Pons50.6
PrefrontalCortex171.6
Prostate41.45
Salivarygland95.15
SkeletalMuscle9.05
Skin28.5
SmoothMuscle58.85
Spinalcord115.7
SubthalamicNucleus83
SuperiorCervicalGanglion16.85
TemporalLobe62.9
Testis33.1
TestisGermCell124.7
TestisIntersitial146.85
TestisLeydigCell98.9
TestisSeminiferousTubule92.75
Thalamus109.85
Thymus31.15
Thyroid189.55
Tongue24.1
Tonsil77.45
Trachea54.85
TrigeminalGanglion23.3
Uterus53.85
UterusCorpus33.05
WholeBlood374.15
Wholebrain63.1
colon37.3
pineal_day185.52
pineal_night178.1
retina107.475
small_intestine45.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P201996
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.74 ± 0.22
Basal Forebrain10.58 ± 0.18
Basal Part of Pons10.63 ± 0.16
Cerebellar Cortex10.86 ± 0.12
Cerebellar Nuclei10.68 ± 0.15
Claustrum10.82 ± 0.17
Epithalamus10.52 ± 0.29
Frontal Lobe10.68 ± 0.16
Globus Pallidus10.52 ± 0.13
Hypothalamus10.65 ± 0.2
Insula10.8 ± 0.19
Limbic Lobe10.52 ± 0.18
Mesencephalon10.68 ± 0.2
Myelencephalon10.63 ± 0.18
Occipital Lobe10.55 ± 0.2
Parietal Lobe10.74 ± 0.18
Pontine Tegmentum10.67 ± 0.18
Striatum10.34 ± 0.17
Subthalamus10.8 ± 0.21
Temporal Lobe10.66 ± 0.15
Thalamus10.69 ± 0.18
White Matter10.8 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
WacCBCerebellum39.8
65
WacCTXCerebral cortex100
100
WacHIPHippocampal region94.21
100
WacHPFHippocampal formation97.85
100
WacHYHypothalamus72.93
64.86
WacLSXLateral septal complex100
96.25
WacMBMidbrain73.16
74.24
WacMYMedulla65.15
80.55
WacOLFOlfactory bulb83.77
88.08
WacPPons64.88
74.12
WacPALPallidum72.03
73.5
WacRHPRetrohippocampal region100
100
WacsAMYStriatum-like amygdalar nuclei81.24
68.96
WacSTRStriatum80.38
66.51
WacSTRdStriatum dorsal region81.09
67.34
WacSTRvStriatum ventral region72.43
55.6
WacTHThalamus95.67
97.61
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027933 19 448 466 STCSLTPALAAHFSENLIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved