AutismKB 2.0

Annotation Detail for PRR16


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Basic Information Top
Gene Symbol:PRR16 ( DSC54,MGC104614 )
Gene Full Name: proline rich 16
Band: 5q23.1
Quick LinksEntrez ID:51334; OMIM: NA; Uniprot ID:PRR16_HUMAN; ENSEMBL ID: ENSG00000184838; HGNC ID: 29654
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal20 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart3 / 8962633
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220014_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.95
Adipocyte7.5
AdrenalCortex10.2
Adrenalgland6.95
Amygdala7.35
Appendix9.5
AtrioventricularNode8.1
BDCA4+_DentriticCells7.3
Bonemarrow8.45
BronchialEpithelialCells7.2
CD105+_Endothelial7.4
CD14+_Monocytes8.05
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid9.1
CD34+8.95
CD4+_Tcells7.5
CD56+_NKCells8.35
CD71+_EarlyErythroid7.35
CD8+_Tcells6.75
CardiacMyocytes14.3
Caudatenucleus6.8
Cerebellum6.4
CerebellumPeduncles9.65
CiliaryGanglion9.1
CingulateCortex8.05
Colorectaladenocarcinoma7.55
DorsalRootGanglion7.2
FetalThyroid7.65
Fetalbrain7.25
Fetalliver6.8
Fetallung5.95
GlobusPallidus6.25
Heart13.75
Hypothalamus7.75
Kidney7.05
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)5.65
Liver12.15
Lung8.2
Lymphnode6.05
Lymphoma_burkitts(Daudi)10.25
Lymphoma_burkitts(Raji)11.9
MedullaOblongata6.7
OccipitalLobe6.7
OlfactoryBulb5.85
Ovary6.65
Pancreas6.5
PancreaticIslet8.35
ParietalLobe9.2
Pituitary8.85
Placenta7.5
Pons7.9
PrefrontalCortex8.65
Prostate8.6
Salivarygland6.5
SkeletalMuscle12.3
Skin10.4
SmoothMuscle13.1
Spinalcord8
SubthalamicNucleus7.4
SuperiorCervicalGanglion14.35
TemporalLobe7.35
Testis6.45
TestisGermCell5.95
TestisIntersitial6.85
TestisLeydigCell8.05
TestisSeminiferousTubule6.4
Thalamus8
Thymus5.65
Thyroid8.9
Tongue8.85
Tonsil7.6
Trachea6.3
TrigeminalGanglion11.15
Uterus8.1
UterusCorpus8.2
WholeBlood8.1
Wholebrain6
colon7.55
pineal_day225.74
pineal_night198.78
retina9.175
small_intestine7.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P20746
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.11 ± 0.8
Basal Forebrain3.62 ± 0.42
Basal Part of Pons4.45 ± 0.3
Cerebellar Cortex4.25 ± 0.43
Cerebellar Nuclei3.53 ± 0.5
Claustrum3.9 ± 0.91
Epithalamus3.65 ± 0.88
Frontal Lobe3.58 ± 0.65
Globus Pallidus2.87 ± 0.73
Hypothalamus4.21 ± 0.53
Insula3.29 ± 0.89
Limbic Lobe3.9 ± 0.67
Mesencephalon4.03 ± 0.66
Myelencephalon3.84 ± 0.67
Occipital Lobe4.56 ± 0.73
Parietal Lobe3.91 ± 0.63
Pontine Tegmentum3.43 ± 0.8
Striatum3.73 ± 0.5
Subthalamus4.83 ± 0.13
Temporal Lobe3.78 ± 0.7
Thalamus3.52 ± 0.86
White Matter2.72 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prr16CBCerebellum1.31
2.03
Prr16CTXCerebral cortex1.39
1.18
Prr16HIPHippocampal region1.43
1.64
Prr16HPFHippocampal formation1.05
1.09
Prr16HYHypothalamus0.17
0.23
Prr16LSXLateral septal complex0.04
0
Prr16MBMidbrain0.56
0.66
Prr16MYMedulla1.26
1.51
Prr16OLFOlfactory bulb2.26
2.82
Prr16PPons0.73
0.9
Prr16PALPallidum0.18
0.18
Prr16RHPRetrohippocampal region0.6
0.52
Prr16sAMYStriatum-like amygdalar nuclei0.62
0.49
Prr16STRStriatum0.46
0.4
Prr16STRdStriatum dorsal region0.51
0.47
Prr16STRvStriatum ventral region0.38
0.29
Prr16THThalamus0.85
0.87
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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