AutismKB 2.0

Annotation Detail for FZR1


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Basic Information Top
Gene Symbol:FZR1 ( CDC20C,CDH1,FZR,FZR2,HCDH,HCDH1,KIAA1242 )
Gene Full Name: fizzy/cell division cycle 20 related 1 (Drosophila)
Band: 19p13.3
Quick LinksEntrez ID:51343; OMIM: 603619; Uniprot ID:FZR_HUMAN; ENSEMBL ID: ENSG00000105325; HGNC ID: 24824
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst6 / 6231996
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal82 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow2 / 4880140
brain28 / 110098925
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye11 / 21105452
heart3 / 8962633
intestine6 / 23447225
kidney9 / 21177742
larynx2 / 2414582
liver1 / 2077434
lung13 / 33697438
lymph7 / 44270158
lymph node2 / 9161021
mammary gland7 / 15327145
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas10 / 21481246
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate1 / 1893455
salivary gland3 / 20155148
skin5 / 21057423
spleen1 / 5395218
stomach2 / 9661920
testis8 / 33044224
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209414_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.85
Adipocyte9.5
AdrenalCortex10.3
Adrenalgland8.05
Amygdala10.25
Appendix9.5
AtrioventricularNode9.4
BDCA4+_DentriticCells10.35
Bonemarrow9.85
BronchialEpithelialCells9.45
CD105+_Endothelial9.75
CD14+_Monocytes15
CD19+_BCells(neg._sel.)10.35
CD33+_Myeloid13.15
CD34+12.25
CD4+_Tcells10.85
CD56+_NKCells11.95
CD71+_EarlyErythroid24.6
CD8+_Tcells8.7
CardiacMyocytes12.15
Caudatenucleus8.7
Cerebellum7.75
CerebellumPeduncles10.8
CiliaryGanglion6.65
CingulateCortex10
Colorectaladenocarcinoma9.1
DorsalRootGanglion7.5
FetalThyroid9.3
Fetalbrain9.55
Fetalliver8
Fetallung6.8
GlobusPallidus7.25
Heart13.2
Hypothalamus10.3
Kidney7.65
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-608.5
Leukemialymphoblastic(MOLT-4)7.7
Liver12.5
Lung10.75
Lymphnode8.25
Lymphoma_burkitts(Daudi)12.55
Lymphoma_burkitts(Raji)13.2
MedullaOblongata8.7
OccipitalLobe8.65
OlfactoryBulb7.55
Ovary6.3
Pancreas7.65
PancreaticIslet10.2
ParietalLobe10.2
Pituitary11.15
Placenta10
Pons9.3
PrefrontalCortex12.2
Prostate11.25
Salivarygland7.85
SkeletalMuscle13.2
Skin7.6
SmoothMuscle10.9
Spinalcord10.25
SubthalamicNucleus8.8
SuperiorCervicalGanglion10.75
TemporalLobe8.8
Testis8.2
TestisGermCell7.75
TestisIntersitial8
TestisLeydigCell9.4
TestisSeminiferousTubule8.25
Thalamus9.8
Thymus7.5
Thyroid11.3
Tongue9.6
Tonsil9.3
Trachea8.05
TrigeminalGanglion10
Uterus7.85
UterusCorpus8.4
WholeBlood10.45
Wholebrain8.3
colon9.65
pineal_day12.1
pineal_night12.48
retina11.7
small_intestine9.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P142325
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.49
Basal Forebrain5.83 ± 0.12
Basal Part of Pons6.43 ± 0.32
Cerebellar Cortex5.95 ± 0.35
Cerebellar Nuclei5.63 ± 0.59
Claustrum6.21 ± 0.36
Epithalamus5.52 ± 0.64
Frontal Lobe6.26 ± 0.33
Globus Pallidus5.3 ± 0.52
Hypothalamus5.87 ± 0.38
Insula6.29 ± 0.24
Limbic Lobe6.29 ± 0.29
Mesencephalon5.91 ± 0.42
Myelencephalon6.03 ± 0.46
Occipital Lobe5.61 ± 0.36
Parietal Lobe6.05 ± 0.39
Pontine Tegmentum5.96 ± 0.4
Striatum5.65 ± 0.47
Subthalamus5.84 ± 0.48
Temporal Lobe6.24 ± 0.37
Thalamus6.08 ± 0.29
White Matter5.7 ± 0.53
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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