AutismKB 2.0

Annotation Detail for CDC40


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDC40 ( EHB3,FLJ10564,MGC102802,PRP17,PRPF17 )
Gene Full Name: cell division cycle 40 homolog (S. cerevisiae)
Band: 6q21
Quick LinksEntrez ID:51362; OMIM: 605585; Uniprot ID:PRP17_HUMAN; ENSEMBL ID: ENSG00000168438; HGNC ID: 17350
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst3 / 6231948
fetus23 / 56401240
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal132 / 336030739
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood3 / 12347824
bone5 / 7165569
bone marrow6 / 48801122
brain46 / 110098941
cervix6 / 48171124
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine12 / 23447251
kidney10 / 21177747
larynx1 / 2414541
liver5 / 20774324
lung11 / 33697432
lymph1 / 4427022
lymph node6 / 9161065
mammary gland22 / 153271143
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus10 / 23287842
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203377_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.1
Adipocyte7.5
AdrenalCortex8.85
Adrenalgland6.7
Amygdala8.1
Appendix9.3
AtrioventricularNode8.3
BDCA4+_DentriticCells19.05
Bonemarrow8.05
BronchialEpithelialCells7.35
CD105+_Endothelial7.9
CD14+_Monocytes8.55
CD19+_BCells(neg._sel.)19.85
CD33+_Myeloid15.15
CD34+9.6
CD4+_Tcells8.45
CD56+_NKCells9.55
CD71+_EarlyErythroid10
CD8+_Tcells11.3
CardiacMyocytes15.55
Caudatenucleus7.95
Cerebellum6.45
CerebellumPeduncles9.4
CiliaryGanglion8.1
CingulateCortex8.6
Colorectaladenocarcinoma7.7
DorsalRootGanglion6.8
FetalThyroid7.8
Fetalbrain7.15
Fetalliver6.8
Fetallung5.65
GlobusPallidus6.2
Heart13.25
Hypothalamus7.95
Kidney7.3
Leukemia_chronicMyelogenousK-5626.85
Leukemia_promyelocytic-HL-606.75
Leukemialymphoblastic(MOLT-4)5.7
Liver11.75
Lung8.45
Lymphnode6.45
Lymphoma_burkitts(Daudi)10.45
Lymphoma_burkitts(Raji)12.45
MedullaOblongata6.75
OccipitalLobe6.95
OlfactoryBulb5.9
Ovary7.6
Pancreas6.4
PancreaticIslet8.45
ParietalLobe8.55
Pituitary8.95
Placenta7.4
Pons7.8
PrefrontalCortex9
Prostate8.55
Salivarygland6.9
SkeletalMuscle13.75
Skin7.4
SmoothMuscle8.75
Spinalcord8.15
SubthalamicNucleus7.4
SuperiorCervicalGanglion13.25
TemporalLobe7.4
Testis6.6
TestisGermCell6.35
TestisIntersitial7.9
TestisLeydigCell8.5
TestisSeminiferousTubule6.75
Thalamus8.15
Thymus5.65
Thyroid8.95
Tongue9.15
Tonsil7.75
Trachea6.35
TrigeminalGanglion10.25
Uterus6
UterusCorpus8.15
WholeBlood8.4
Wholebrain5.9
colon7.8
pineal_day9.38
pineal_night9.36
retina9.55
small_intestine7.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P414786
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.96 ± 0.71
Basal Forebrain7.89 ± 0.29
Basal Part of Pons8.16 ± 0.18
Cerebellar Cortex7.88 ± 0.13
Cerebellar Nuclei7.62 ± 0.45
Claustrum8.41 ± 0.4
Epithalamus7.8 ± 0.36
Frontal Lobe8.39 ± 0.36
Globus Pallidus6.91 ± 0.52
Hypothalamus7.9 ± 0.26
Insula8.46 ± 0.33
Limbic Lobe8.37 ± 0.66
Mesencephalon7.93 ± 0.37
Myelencephalon8.07 ± 0.39
Occipital Lobe7.81 ± 0.62
Parietal Lobe8.25 ± 0.5
Pontine Tegmentum8.23 ± 0.6
Striatum8.48 ± 0.61
Subthalamus8.03 ± 0.23
Temporal Lobe8.38 ± 0.42
Thalamus7.9 ± 0.37
White Matter7.59 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc40CBCerebellum3.47
4.31
Cdc40CTXCerebral cortex13.78
8.86
Cdc40HIPHippocampal region18.55
16.48
Cdc40HPFHippocampal formation15.38
12.7
Cdc40HYHypothalamus0.72
0.68
Cdc40LSXLateral septal complex0.49
0.45
Cdc40MBMidbrain1.29
1.27
Cdc40MYMedulla3.06
3.37
Cdc40OLFOlfactory bulb9.93
7.78
Cdc40PPons1.25
1.11
Cdc40PALPallidum0.87
0.7
Cdc40RHPRetrohippocampal region9.83
7.13
Cdc40sAMYStriatum-like amygdalar nuclei1.49
0.97
Cdc40STRStriatum2.82
1.8
Cdc40STRdStriatum dorsal region3
2
Cdc40STRvStriatum ventral region4.01
2.15
Cdc40THThalamus4.09
3.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00480088 14 253 266 SYLHIPQDVGVNLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved