AutismKB 2.0

Annotation Detail for PLA1A


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Basic Information Top
Gene Symbol:PLA1A ( PS-PLA1,PSPLA1 )
Gene Full Name: phospholipase A1 member A
Band: 3q13.33
Quick LinksEntrez ID:51365; OMIM: 607460; Uniprot ID:PLA1A_HUMAN; ENSEMBL ID: ENSG00000144837; HGNC ID: 17661
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal37 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid5 / 20539243
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219584_at
Cell line Expression level Expression bar
721_B_lymphoblasts316.3
Adipocyte5.7
AdrenalCortex6.35
Adrenalgland4.8
Amygdala5.8
Appendix6.55
AtrioventricularNode4.5
BDCA4+_DentriticCells6.3
Bonemarrow5.9
BronchialEpithelialCells5.4
CD105+_Endothelial5.85
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6.2
CD33+_Myeloid7.5
CD34+7.35
CD4+_Tcells6
CD56+_NKCells6.85
CD71+_EarlyErythroid5.35
CD8+_Tcells5.6
CardiacMyocytes7.2
Caudatenucleus5.15
Cerebellum4.65
CerebellumPeduncles6.5
CiliaryGanglion4.15
CingulateCortex5.95
Colorectaladenocarcinoma5.8
DorsalRootGanglion4.85
FetalThyroid5.6
Fetalbrain5.75
Fetalliver5.05
Fetallung4.9
GlobusPallidus4.2
Heart7.55
Hypothalamus6.2
Kidney4.7
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.65
Liver8.15
Lung6.5
Lymphnode13.85
Lymphoma_burkitts(Daudi)7.3
Lymphoma_burkitts(Raji)8.05
MedullaOblongata5.35
OccipitalLobe5.2
OlfactoryBulb4.6
Ovary3.95
Pancreas4.6
PancreaticIslet6.15
ParietalLobe6.1
Pituitary6.7
Placenta6.1
Pons5.45
PrefrontalCortex7.4
Prostate6.75
Salivarygland4.65
SkeletalMuscle7.55
Skin4.75
SmoothMuscle6.55
Spinalcord6.2
SubthalamicNucleus5.25
SuperiorCervicalGanglion11.7
TemporalLobe5.25
Testis5
TestisGermCell4.9
TestisIntersitial4.85
TestisLeydigCell7.95
TestisSeminiferousTubule5
Thalamus5.8
Thymus4.5
Thyroid7
Tongue5.85
Tonsil5.6
Trachea4.8
TrigeminalGanglion6.15
Uterus4.8
UterusCorpus5.6
WholeBlood6.3
Wholebrain4.95
colon5.75
pineal_day7.1
pineal_night6.94
retina38.4
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P294408
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.48 ± 1.03
Basal Forebrain1.99 ± 0.24
Basal Part of Pons1.8 ± 0.52
Cerebellar Cortex1.85 ± 0.54
Cerebellar Nuclei2.37 ± 0.71
Claustrum2.86 ± 0.75
Epithalamus2.33 ± 0.62
Frontal Lobe1.97 ± 0.64
Globus Pallidus3.27 ± 0.69
Hypothalamus2.05 ± 0.72
Insula1.99 ± 0.67
Limbic Lobe2.07 ± 0.66
Mesencephalon2.39 ± 0.72
Myelencephalon2.23 ± 0.64
Occipital Lobe2.27 ± 0.57
Parietal Lobe2.16 ± 0.7
Pontine Tegmentum2.14 ± 0.65
Striatum2.7 ± 0.69
Subthalamus2.49 ± 0.84
Temporal Lobe2.02 ± 0.63
Thalamus2.22 ± 0.57
White Matter3.08 ± 1.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pla1aCBCerebellum0
0
Pla1aCTXCerebral cortex0
0
Pla1aHIPHippocampal region0
0
Pla1aHPFHippocampal formation0
0
Pla1aHYHypothalamus0
0
Pla1aLSXLateral septal complex0
0
Pla1aMBMidbrain0
0
Pla1aMYMedulla0
0
Pla1aOLFOlfactory bulb0
0
Pla1aPPons0
0
Pla1aPALPallidum0
0
Pla1aRHPRetrohippocampal region0
0
Pla1asAMYStriatum-like amygdalar nuclei0
0
Pla1aSTRStriatum0
0
Pla1aSTRdStriatum dorsal region0
0
Pla1aSTRvStriatum ventral region0
0
Pla1aTHThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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