AutismKB 2.0

Annotation Detail for POP5


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Basic Information Top
Gene Symbol:POP5 ( HSPC004,RPP2,RPP20,hPop5 )
Gene Full Name: processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
Band: 12q24.31
Quick LinksEntrez ID:51367; OMIM: 609992; Uniprot ID:POP5_HUMAN; ENSEMBL ID: ENSG00000167272; HGNC ID: 17689
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor14 / 114246122
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal70 / 336030720
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone6 / 7165583
bone marrow1 / 4880120
brain9 / 11009898
cervix3 / 4817162
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine18 / 23447276
kidney4 / 21177718
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph1 / 4427022
lymph node6 / 9161065
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta4 / 28082514
prostate8 / 18934542
salivary gland1 / 2015549
skin9 / 21057442
spleen1 / 5395218
stomach1 / 9661910
testis3 / 3304429
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204839_at
Cell line Expression level Expression bar
721_B_lymphoblasts220.15
Adipocyte24.8
AdrenalCortex16.2
Adrenalgland23.2
Amygdala11.9
Appendix13.95
AtrioventricularNode9
BDCA4+_DentriticCells121.9
Bonemarrow12.55
BronchialEpithelialCells47.75
CD105+_Endothelial33.65
CD14+_Monocytes44.7
CD19+_BCells(neg._sel.)159.7
CD33+_Myeloid56
CD34+114.45
CD4+_Tcells101.15
CD56+_NKCells125.6
CD71+_EarlyErythroid14
CD8+_Tcells141.35
CardiacMyocytes12.35
Caudatenucleus11.9
Cerebellum9.2
CerebellumPeduncles12.6
CiliaryGanglion8
CingulateCortex13.4
Colorectaladenocarcinoma14.7
DorsalRootGanglion8.9
FetalThyroid18.2
Fetalbrain13.2
Fetalliver10.8
Fetallung9.9
GlobusPallidus5.65
Heart24.85
Hypothalamus31.05
Kidney25.6
Leukemia_chronicMyelogenousK-56222.9
Leukemia_promyelocytic-HL-60131.1
Leukemialymphoblastic(MOLT-4)37.45
Liver16.85
Lung42.6
Lymphnode33.75
Lymphoma_burkitts(Daudi)23.35
Lymphoma_burkitts(Raji)23.9
MedullaOblongata9.95
OccipitalLobe10.05
OlfactoryBulb10.95
Ovary8.3
Pancreas16.85
PancreaticIslet38.5
ParietalLobe12.8
Pituitary19.85
Placenta9.7
Pons10.25
PrefrontalCortex21.25
Prostate31.5
Salivarygland19.15
SkeletalMuscle7.6
Skin9.1
SmoothMuscle23.7
Spinalcord19.65
SubthalamicNucleus8.4
SuperiorCervicalGanglion12.85
TemporalLobe10.35
Testis12.35
TestisGermCell9.2
TestisIntersitial5.4
TestisLeydigCell8.1
TestisSeminiferousTubule6
Thalamus14.4
Thymus83.9
Thyroid52.2
Tongue11.5
Tonsil16.65
Trachea22.4
TrigeminalGanglion11.4
Uterus24.15
UterusCorpus10.45
WholeBlood18
Wholebrain25.25
colon17.35
pineal_day21.38
pineal_night29.82
retina26.725
small_intestine48.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P99216
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.38 ± 0.79
Basal Forebrain5.68 ± 0.23
Basal Part of Pons5.87 ± 0.54
Cerebellar Cortex5.56 ± 0.39
Cerebellar Nuclei5.73 ± 0.52
Claustrum4.87 ± 0.84
Epithalamus6.22 ± 0.56
Frontal Lobe5.81 ± 0.45
Globus Pallidus6.16 ± 0.5
Hypothalamus5.8 ± 0.59
Insula5.76 ± 0.36
Limbic Lobe5.28 ± 0.6
Mesencephalon5.68 ± 0.55
Myelencephalon5.59 ± 0.55
Occipital Lobe5.27 ± 0.47
Parietal Lobe5.62 ± 0.57
Pontine Tegmentum5.54 ± 0.46
Striatum5.38 ± 0.48
Subthalamus5.59 ± 0.52
Temporal Lobe5.71 ± 0.47
Thalamus5.67 ± 0.5
White Matter5.89 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pop5CBCerebellum5.93
7.95
Pop5CTXCerebral cortex40
38.53
Pop5HIPHippocampal region20.37
29.14
Pop5HPFHippocampal formation15.29
19.98
Pop5HYHypothalamus1.32
1.38
Pop5LSXLateral septal complex0.36
0.47
Pop5MBMidbrain5.28
8.28
Pop5MYMedulla10.35
19.63
Pop5OLFOlfactory bulb27.48
31.71
Pop5PPons8.49
14.54
Pop5PALPallidum2.81
3.74
Pop5RHPRetrohippocampal region5.29
5.53
Pop5sAMYStriatum-like amygdalar nuclei0.57
0.61
Pop5STRStriatum3.05
2.8
Pop5STRdStriatum dorsal region2.24
2.18
Pop5STRvStriatum ventral region8.62
6.85
Pop5THThalamus5.08
9.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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