AutismKB 2.0

Annotation Detail for ANAPC7


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Basic Information Top
Gene Symbol:ANAPC7 ( APC7 )
Gene Full Name: anaphase promoting complex subunit 7
Band: 12q24.11
Quick LinksEntrez ID:51434; OMIM: 606949; Uniprot ID:APC7_HUMAN; ENSEMBL ID: ENSG00000196510; HGNC ID: 17380
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst8 / 62319128
fetus40 / 56401270
neonate2 / 3109764
infant3 / 23620127
juvenile5 / 5555689
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma3 / 17475171
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor13 / 26384549
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal184 / 336030754
ovarian tumor8 / 76682104
pancreatic tumor23 / 104616219
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor11 / 12494988
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites4 / 4001599
bladder1 / 2975733
blood6 / 12347848
bone3 / 7165541
bone marrow1 / 4880120
brain46 / 110098941
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye11 / 21105452
heart11 / 89626122
intestine14 / 23447259
kidney14 / 21177766
larynx0 / 241450 
liver8 / 20774338
lung19 / 33697456
lymph0 / 442700 
lymph node8 / 9161087
mammary gland6 / 15327139
mouth6 / 6705289
muscle1 / 1077159
nerve3 / 15768190
ovary11 / 102051107
pancreas30 / 214812139
parathyroid4 / 20539194
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate7 / 18934536
salivary gland0 / 201550 
skin15 / 21057471
spleen1 / 5395218
stomach3 / 9661931
testis20 / 33044260
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus25 / 232878107
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P44636
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.57 ± 0.63
Basal Forebrain4.14 ± 0.3
Basal Part of Pons4.39 ± 0.67
Cerebellar Cortex4.77 ± 0.38
Cerebellar Nuclei4.23 ± 0.62
Claustrum4.26 ± 0.86
Epithalamus4.44 ± 0.28
Frontal Lobe4.62 ± 0.52
Globus Pallidus4.13 ± 0.47
Hypothalamus4.7 ± 0.65
Insula4.52 ± 0.3
Limbic Lobe4.45 ± 0.51
Mesencephalon4.4 ± 0.54
Myelencephalon4.45 ± 0.52
Occipital Lobe4.18 ± 0.64
Parietal Lobe4.56 ± 0.41
Pontine Tegmentum4.52 ± 0.55
Striatum4.33 ± 0.5
Subthalamus4.51 ± 0.28
Temporal Lobe4.54 ± 0.48
Thalamus4.38 ± 0.49
White Matter4.73 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anapc7CBCerebellum26.4
44.59
Anapc7CTXCerebral cortex71.85
58.61
Anapc7HIPHippocampal region40.14
50.69
Anapc7HPFHippocampal formation49.73
53.59
Anapc7HYHypothalamus24.25
19.72
Anapc7LSXLateral septal complex37.26
28.04
Anapc7MBMidbrain29.13
26.88
Anapc7MYMedulla29.34
33.87
Anapc7OLFOlfactory bulb55.84
46.96
Anapc7PPons29.84
32.15
Anapc7PALPallidum27.95
26.07
Anapc7RHPRetrohippocampal region68.22
60.36
Anapc7sAMYStriatum-like amygdalar nuclei52.69
39.68
Anapc7STRStriatum25.05
19.2
Anapc7STRdStriatum dorsal region19.79
15.72
Anapc7STRvStriatum ventral region22.63
16.19
Anapc7THThalamus67.4
64.85
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
APC7_HUMAN_1 8 1 8 MNVIDHVR PRIDE
PAp00002038 13 318 330 EGRLEDVENLGCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018