AutismKB 2.0

Annotation Detail for SCARA3


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Basic Information Top
Gene Symbol:SCARA3 ( APC7,CSR,CSR1,MSLR1,MSRL1 )
Gene Full Name: scavenger receptor class A, member 3
Band: 8p21.1
Quick LinksEntrez ID:51435; OMIM: 602728; Uniprot ID:SCAR3_HUMAN; ENSEMBL ID: ENSG00000168077; HGNC ID: 19000
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal48 / 336030714
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain16 / 110098914
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular3 / 5178057
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219416_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.6
Adipocyte9.5
AdrenalCortex5.2
Adrenalgland4.55
Amygdala8.8
Appendix5.4
AtrioventricularNode4.65
BDCA4+_DentriticCells4.9
Bonemarrow5.1
BronchialEpithelialCells4.75
CD105+_Endothelial4.8
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)4.55
CD33+_Myeloid6.2
CD34+5.6
CD4+_Tcells5
CD56+_NKCells5.05
CD71+_EarlyErythroid4.9
CD8+_Tcells4.4
CardiacMyocytes7.75
Caudatenucleus5.5
Cerebellum9.65
CerebellumPeduncles5.85
CiliaryGanglion3.7
CingulateCortex5.85
Colorectaladenocarcinoma7.1
DorsalRootGanglion4.1
FetalThyroid6.25
Fetalbrain6.2
Fetalliver5.1
Fetallung9.3
GlobusPallidus3.95
Heart6.75
Hypothalamus7.75
Kidney4.1
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)4
Liver6.85
Lung6.85
Lymphnode4.45
Lymphoma_burkitts(Daudi)6.55
Lymphoma_burkitts(Raji)7
MedullaOblongata4.9
OccipitalLobe5.55
OlfactoryBulb6.55
Ovary3.6
Pancreas4.35
PancreaticIslet5.85
ParietalLobe5.55
Pituitary6.4
Placenta10
Pons6.85
PrefrontalCortex9.65
Prostate8.4
Salivarygland5.7
SkeletalMuscle5.9
Skin4.05
SmoothMuscle7.4
Spinalcord15.45
SubthalamicNucleus5.05
SuperiorCervicalGanglion6.65
TemporalLobe9.95
Testis4.7
TestisGermCell4.55
TestisIntersitial4.6
TestisLeydigCell5.3
TestisSeminiferousTubule4.35
Thalamus11.85
Thymus5.3
Thyroid7.45
Tongue5.25
Tonsil7.45
Trachea13
TrigeminalGanglion12.05
Uterus21.1
UterusCorpus49.85
WholeBlood4.85
Wholebrain8.7
colon5.1
pineal_day16.64
pineal_night10.42
retina14.65
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9964_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.55 ± 0.34
Basal Forebrain7.65 ± 0.33
Basal Part of Pons7.2 ± 0.22
Cerebellar Cortex7.46 ± 0.33
Cerebellar Nuclei7.74 ± 0.5
Claustrum7.7 ± 0.37
Epithalamus8.03 ± 0.41
Frontal Lobe7.6 ± 0.38
Globus Pallidus8 ± 0.44
Hypothalamus7.78 ± 0.34
Insula7.45 ± 0.33
Limbic Lobe7.46 ± 0.41
Mesencephalon7.83 ± 0.45
Myelencephalon7.78 ± 0.38
Occipital Lobe7.86 ± 0.46
Parietal Lobe7.66 ± 0.38
Pontine Tegmentum7.7 ± 0.32
Striatum8.02 ± 0.49
Subthalamus7.33 ± 0.3
Temporal Lobe7.5 ± 0.4
Thalamus8.04 ± 0.33
White Matter7.62 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scara3CBCerebellum12.43
13.62
Scara3CTXCerebral cortex25.29
15.47
Scara3HIPHippocampal region17.44
12.51
Scara3HPFHippocampal formation22.53
15.79
Scara3HYHypothalamus2.4
1.72
Scara3LSXLateral septal complex12.1
10.82
Scara3MBMidbrain6.43
6.93
Scara3MYMedulla11.74
12.19
Scara3OLFOlfactory bulb20.47
10.61
Scara3PPons13.22
13.31
Scara3PALPallidum5.75
3.78
Scara3RHPRetrohippocampal region29.45
19.18
Scara3sAMYStriatum-like amygdalar nuclei9.95
5.98
Scara3STRStriatum15.8
10.15
Scara3STRdStriatum dorsal region17.22
11.26
Scara3STRvStriatum ventral region14.68
7.85
Scara3THThalamus2.77
2.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018