AutismKB 2.0

Annotation Detail for C22orf28


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Basic Information Top
Gene Symbol:C22orf28 ( DJ149A16.6,RP1-149A16.6 )
Gene Full Name: chromosome 22 open reading frame 28
Band: 22q12
Quick LinksEntrez ID:51493; OMIM: NA; Uniprot ID:CV028_HUMAN; ENSEMBL ID: ENSG00000100220; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus55 / 56401297
neonate9 / 31097289
infant7 / 23620296
juvenile16 / 55556287
adult260 / 1939121134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor16 / 94178169
cervical tumor10 / 34366290
chondrosarcoma9 / 82823108
colorectal tumor25 / 114246218
esophageal tumor7 / 17290404
gastrointestinal tumor16 / 119369134
germ cell tumor76 / 263845288
glioma24 / 106883224
head and neck tumor25 / 136302183
kidney tumor14 / 68959203
leukemia13 / 95842135
liver tumor21 / 96359217
lung tumor30 / 103127290
lymphoma18 / 71755250
non-neoplasia29 / 97250298
normal582 / 3360307173
ovarian tumor24 / 76682312
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS71 / 125680564
prostate cancer8 / 10268077
retinoblastoma5 / 46356107
skin tumor44 / 124949352
soft tissue/muscle tissue tumor50 / 125191399
uterine tumor18 / 90257199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland19 / 33197572
ascites9 / 40015224
bladder11 / 29757369
blood27 / 123478218
bone5 / 7165569
bone marrow2 / 4880140
brain223 / 1100989202
cervix14 / 48171290
connective tissue39 / 149255261
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus8 / 20209395
eye25 / 211054118
heart20 / 89626223
intestine55 / 234472234
kidney44 / 211777207
larynx5 / 24145207
liver40 / 207743192
lung61 / 336974181
lymph9 / 44270203
lymph node4 / 9161043
mammary gland29 / 153271189
mouth6 / 6705289
muscle45 / 107715417
nerve0 / 157680 
ovary39 / 102051382
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx18 / 41328435
pituitary gland0 / 165850 
placenta61 / 280825217
prostate27 / 189345142
salivary gland12 / 20155595
skin59 / 210574280
spleen5 / 5395292
stomach15 / 96619155
testis55 / 330442166
thymus35 / 81131431
thyroid10 / 47473210
tonsil2 / 16999117
trachea8 / 52413152
umbilical cord3 / 13680219
uterus52 / 232878223
vascular19 / 51780366
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200042_at
Cell line Expression level Expression bar
721_B_lymphoblasts855.4
Adipocyte191.9
AdrenalCortex125.1
Adrenalgland125.9
Amygdala125
Appendix123.8
AtrioventricularNode61.55
BDCA4+_DentriticCells432.4
Bonemarrow131.25
BronchialEpithelialCells395.4
CD105+_Endothelial460.15
CD14+_Monocytes390.4
CD19+_BCells(neg._sel.)364.1
CD33+_Myeloid324.5
CD34+547.45
CD4+_Tcells213.25
CD56+_NKCells357.85
CD71+_EarlyErythroid134.65
CD8+_Tcells171.95
CardiacMyocytes172.2
Caudatenucleus122.1
Cerebellum122.25
CerebellumPeduncles193.6
CiliaryGanglion45.55
CingulateCortex133.2
Colorectaladenocarcinoma125.35
DorsalRootGanglion94.55
FetalThyroid235.95
Fetalbrain125.5
Fetalliver153.4
Fetallung201.65
GlobusPallidus70.1
Heart68.3
Hypothalamus229.95
Kidney208.4
Leukemia_chronicMyelogenousK-562292.75
Leukemia_promyelocytic-HL-60302.35
Leukemialymphoblastic(MOLT-4)264
Liver144.8
Lung211.8
Lymphnode175.7
Lymphoma_burkitts(Daudi)112.95
Lymphoma_burkitts(Raji)206.8
MedullaOblongata138.6
OccipitalLobe149.35
OlfactoryBulb102.8
Ovary76.7
Pancreas116.95
PancreaticIslet313.9
ParietalLobe140.9
Pituitary265.05
Placenta278.95
Pons102.3
PrefrontalCortex165.85
Prostate241.75
Salivarygland91.35
SkeletalMuscle56.65
Skin91.85
SmoothMuscle489.35
Spinalcord204.6
SubthalamicNucleus109.25
SuperiorCervicalGanglion50.2
TemporalLobe117.9
Testis255.8
TestisGermCell173.7
TestisIntersitial138.4
TestisLeydigCell149.3
TestisSeminiferousTubule117.95
Thalamus189.05
Thymus290.7
Thyroid228.4
Tongue141.25
Tonsil263.95
Trachea124
TrigeminalGanglion71.95
Uterus120.85
UterusCorpus145.05
WholeBlood136.1
Wholebrain161.85
colon298
pineal_day308.14
pineal_night290.56
retina270.475
small_intestine469.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P68892
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.11 ± 0.52
Basal Forebrain7.57 ± 0.2
Basal Part of Pons7.92 ± 0.35
Cerebellar Cortex7.82 ± 0.35
Cerebellar Nuclei7.74 ± 0.37
Claustrum7.07 ± 0.64
Epithalamus7.92 ± 0.27
Frontal Lobe7.81 ± 0.35
Globus Pallidus7.68 ± 0.24
Hypothalamus8.11 ± 0.21
Insula7.76 ± 0.31
Limbic Lobe7.32 ± 0.49
Mesencephalon7.61 ± 0.4
Myelencephalon7.56 ± 0.49
Occipital Lobe7.03 ± 0.48
Parietal Lobe7.58 ± 0.43
Pontine Tegmentum7.56 ± 0.45
Striatum6.95 ± 0.3
Subthalamus7.94 ± 0.34
Temporal Lobe7.72 ± 0.37
Thalamus7.57 ± 0.39
White Matter8.14 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D10Wsu52eCBCerebellum21.33
43.61
D10Wsu52eCTXCerebral cortex100
100
D10Wsu52eHIPHippocampal region100
100
D10Wsu52eHPFHippocampal formation94.29
100
D10Wsu52eHYHypothalamus88.21
95.68
D10Wsu52eLSXLateral septal complex89.27
86.9
D10Wsu52eMBMidbrain54.85
71.06
D10Wsu52eMYMedulla34.7
54.26
D10Wsu52eOLFOlfactory bulb78.18
88.86
D10Wsu52ePPons45.38
67.02
D10Wsu52ePALPallidum76.88
96.27
D10Wsu52eRHPRetrohippocampal region73.55
75.19
D10Wsu52esAMYStriatum-like amygdalar nuclei77.93
74.88
D10Wsu52eSTRStriatum77.08
69.78
D10Wsu52eSTRdStriatum dorsal region73.22
65.37
D10Wsu52eSTRvStriatum ventral region88.36
79.63
D10Wsu52eTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CV028_HUMAN_251 12 251 262 GQVCVMIHSGSR PRIDE
CV028_HUMAN_441 19 441 459 NLDFQDVLDKLADMGIAIR PRIDE
PAp00002046 17 182 198 EGYAWAEDKEHCEEYGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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