AutismKB 2.0

Annotation Detail for PDE9A


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Basic Information Top
Gene Symbol:PDE9A ( FLJ90181,HSPDE9A2 )
Gene Full Name: phosphodiesterase 9A
Band: 21q22.3
Quick LinksEntrez ID:5152; OMIM: 602973; Uniprot ID:PDE9A_HUMAN; ENSEMBL ID: ENSG00000160191; HGNC ID: 8795
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal88 / 336030726
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer14 / 102680136
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain22 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine22 / 23447293
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph1 / 4427022
lymph node1 / 9161010
mammary gland1 / 1532716
mouth3 / 6705244
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate36 / 189345190
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis5 / 33044215
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205593_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.1
AdrenalCortex4.5
Adrenalgland3.6
Amygdala4.45
Appendix4.2
AtrioventricularNode3.3
BDCA4+_DentriticCells4.65
Bonemarrow4.15
BronchialEpithelialCells4.1
CD105+_Endothelial4.25
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.25
CD34+5.25
CD4+_Tcells5.7
CD56+_NKCells4.95
CD71+_EarlyErythroid3.9
CD8+_Tcells4.05
CardiacMyocytes5.6
Caudatenucleus3.8
Cerebellum3.45
CerebellumPeduncles4.75
CiliaryGanglion3
CingulateCortex4.3
Colorectaladenocarcinoma6.75
DorsalRootGanglion3.25
FetalThyroid4.05
Fetalbrain16.3
Fetalliver3.65
Fetallung3.55
GlobusPallidus3.1
Heart5.5
Hypothalamus4.65
Kidney3.45
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.35
Liver5.6
Lung4.6
Lymphnode3.55
Lymphoma_burkitts(Daudi)5.35
Lymphoma_burkitts(Raji)5.9
MedullaOblongata3.8
OccipitalLobe3.75
OlfactoryBulb12.85
Ovary2.75
Pancreas3.4
PancreaticIslet4.5
ParietalLobe4.45
Pituitary4.85
Placenta4.3
Pons4
PrefrontalCortex5.15
Prostate97.65
Salivarygland3.35
SkeletalMuscle5
Skin3.3
SmoothMuscle4.7
Spinalcord4.5
SubthalamicNucleus3.8
SuperiorCervicalGanglion4.8
TemporalLobe3.85
Testis3.6
TestisGermCell3.45
TestisIntersitial3.5
TestisLeydigCell4.15
TestisSeminiferousTubule3.55
Thalamus4.25
Thymus3.35
Thyroid5.2
Tongue4.1
Tonsil4.05
Trachea3.5
TrigeminalGanglion4.2
Uterus3.4
UterusCorpus3.8
WholeBlood4.55
Wholebrain3.7
colon5
pineal_day5.2
pineal_night5.1
retina5.15
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12822_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.14 ± 0.49
Basal Forebrain4.97 ± 0.43
Basal Part of Pons4.04 ± 0.5
Cerebellar Cortex5.1 ± 0.38
Cerebellar Nuclei4.93 ± 0.41
Claustrum4.43 ± 0.47
Epithalamus4.55 ± 0.5
Frontal Lobe4.41 ± 0.55
Globus Pallidus5.18 ± 0.78
Hypothalamus4.49 ± 0.55
Insula4.31 ± 0.29
Limbic Lobe4.36 ± 0.61
Mesencephalon4.7 ± 0.65
Myelencephalon4.73 ± 0.68
Occipital Lobe5.04 ± 0.77
Parietal Lobe4.5 ± 0.61
Pontine Tegmentum4.79 ± 0.62
Striatum5.66 ± 0.84
Subthalamus4.38 ± 0.66
Temporal Lobe4.47 ± 0.47
Thalamus5.12 ± 0.49
White Matter5.58 ± 0.47
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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