AutismKB 2.0

Annotation Detail for CXXC5


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Basic Information Top
Gene Symbol:CXXC5 ( CF5,RINF,WID )
Gene Full Name: CXXC finger protein 5
Band: 5q31.2
Quick LinksEntrez ID:51523; OMIM: 612752; Uniprot ID:CXXC5_HUMAN; ENSEMBL ID: ENSG00000171604; HGNC ID: 26943
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus44 / 56401278
neonate0 / 310970 
infant1 / 2362042
juvenile4 / 5555671
adult153 / 193912178
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor6 / 34366174
chondrosarcoma9 / 82823108
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor18 / 26384568
glioma27 / 106883252
head and neck tumor5 / 13630236
kidney tumor10 / 68959145
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal252 / 336030774
ovarian tumor20 / 76682260
pancreatic tumor22 / 104616210
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood9 / 12347872
bone6 / 7165583
bone marrow3 / 4880161
brain110 / 110098999
cervix6 / 48171124
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye30 / 211054142
heart7 / 8962678
intestine19 / 23447281
kidney21 / 21177799
larynx0 / 241450 
liver4 / 20774319
lung23 / 33697468
lymph0 / 442700 
lymph node10 / 91610109
mammary gland10 / 15327165
mouth1 / 6705214
muscle5 / 10771546
nerve2 / 15768126
ovary20 / 102051195
pancreas27 / 214812125
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland4 / 16585241
placenta13 / 28082546
prostate7 / 18934536
salivary gland2 / 2015599
skin16 / 21057475
spleen5 / 5395292
stomach6 / 9661962
testis19 / 33044257
thymus5 / 8113161
thyroid1 / 4747321
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord0 / 136800 
uterus19 / 23287881
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P930062
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.25 ± 0.42
Basal Forebrain8.18 ± 0.34
Basal Part of Pons9.09 ± 0.33
Cerebellar Cortex9.05 ± 0.2
Cerebellar Nuclei8.7 ± 0.34
Claustrum8.58 ± 0.46
Epithalamus9.27 ± 0.4
Frontal Lobe8.73 ± 0.34
Globus Pallidus8.25 ± 0.18
Hypothalamus8.62 ± 0.63
Insula8.8 ± 0.13
Limbic Lobe8.4 ± 0.41
Mesencephalon8.4 ± 0.45
Myelencephalon8.62 ± 0.45
Occipital Lobe8.29 ± 0.42
Parietal Lobe8.58 ± 0.37
Pontine Tegmentum8.55 ± 0.44
Striatum7.5 ± 0.42
Subthalamus8.15 ± 0.26
Temporal Lobe8.77 ± 0.27
Thalamus8.74 ± 0.33
White Matter9.13 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cxxc5CBCerebellum74.34
100
Cxxc5CTXCerebral cortex100
95.35
Cxxc5HIPHippocampal region40.84
64.69
Cxxc5HPFHippocampal formation42.62
52.13
Cxxc5HYHypothalamus19.08
14.7
Cxxc5LSXLateral septal complex13.14
10.1
Cxxc5MBMidbrain24.26
20.82
Cxxc5MYMedulla43.65
47.42
Cxxc5OLFOlfactory bulb69.64
69.28
Cxxc5PPons40.87
43.69
Cxxc5PALPallidum19.26
17.1
Cxxc5RHPRetrohippocampal region47.29
37.65
Cxxc5sAMYStriatum-like amygdalar nuclei16.42
13.52
Cxxc5STRStriatum14.46
11.91
Cxxc5STRdStriatum dorsal region13.87
12.12
Cxxc5STRvStriatum ventral region15.58
11
Cxxc5THThalamus47.29
42.54
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018