Annotation Detail for PDE1B
Basic Information Top
| Gene Symbol: | PDE1B ( PDE1B1,PDES1B ) |
|---|---|
| Gene Full Name: | phosphodiesterase 1B, calmodulin-dependent |
| Band: | 12q13.2 |
| Quick Links | Entrez ID:5153; OMIM: 171891; Uniprot ID:PDE1B_HUMAN; ENSEMBL ID: ENSG00000123360; HGNC ID: 8775 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.530871
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 2 / 564012 | 3 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 24 / 1939121 | 12 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 122 / 3360307 | 36 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 |  |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 97 / 1100989 | 88 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 2 / 96619 | 20 | |
| testis | 3 / 330442 | 9 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 206444_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.55 | |
| Adipocyte | 3.6 | |
| AdrenalCortex | 4.5 | |
| Adrenalgland | 3.5 | |
| Amygdala | 4.45 | |
| Appendix | 3.55 | |
| AtrioventricularNode | 2.85 | |
| BDCA4+_DentriticCells | 4 | |
| Bonemarrow | 3.5 | |
| BronchialEpithelialCells | 3.5 | |
| CD105+_Endothelial | 4.55 | |
| CD14+_Monocytes | 3.8 | |
| CD19+_BCells(neg._sel.) | 3.8 | |
| CD33+_Myeloid | 4.6 | |
| CD34+ | 4.55 | |
| CD4+_Tcells | 3.9 | |
| CD56+_NKCells | 4.25 | |
| CD71+_EarlyErythroid | 3.35 | |
| CD8+_Tcells | 3.5 | |
| CardiacMyocytes | 4.5 | |
| Caudatenucleus | 19.8 | |
| Cerebellum | 2.9 | |
| CerebellumPeduncles | 4.05 | |
| CiliaryGanglion | 2.5 | |
| CingulateCortex | 6.15 | |
| Colorectaladenocarcinoma | 3.55 | |
| DorsalRootGanglion | 2.7 | |
| FetalThyroid | 3.6 | |
| Fetalbrain | 3.6 | |
| Fetalliver | 3.45 | |
| Fetallung | 2.95 | |
| GlobusPallidus | 2.65 | |
| Heart | 4.55 | |
| Hypothalamus | 3.9 | |
| Kidney | 3.45 | |
| Leukemia_chronicMyelogenousK-562 | 3.25 | |
| Leukemia_promyelocytic-HL-60 | 3.2 | |
| Leukemialymphoblastic(MOLT-4) | 2.9 | |
| Liver | 4.75 | |
| Lung | 3.95 | |
| Lymphnode | 3.05 | |
| Lymphoma_burkitts(Daudi) | 4.55 | |
| Lymphoma_burkitts(Raji) | 4.95 | |
| MedullaOblongata | 9.7 | |
| OccipitalLobe | 5.05 | |
| OlfactoryBulb | 2.9 | |
| Ovary | 2.35 | |
| Pancreas | 2.9 | |
| PancreaticIslet | 3.8 | |
| ParietalLobe | 5.25 | |
| Pituitary | 4.2 | |
| Placenta | 3.7 | |
| Pons | 12.05 | |
| PrefrontalCortex | 4.75 | |
| Prostate | 4.15 | |
| Salivarygland | 2.85 | |
| SkeletalMuscle | 4.95 | |
| Skin | 2.7 | |
| SmoothMuscle | 4.05 | |
| Spinalcord | 3.85 | |
| SubthalamicNucleus | 7.5 | |
| SuperiorCervicalGanglion | 4 | |
| TemporalLobe | 5.2 | |
| Testis | 3.1 | |
| TestisGermCell | 3 | |
| TestisIntersitial | 3 | |
| TestisLeydigCell | 3.55 | |
| TestisSeminiferousTubule | 3.1 | |
| Thalamus | 4.2 | |
| Thymus | 2.8 | |
| Thyroid | 4.5 | |
| Tongue | 3.5 | |
| Tonsil | 3.5 | |
| Trachea | 3.85 | |
| TrigeminalGanglion | 3.55 | |
| Uterus | 2.9 | |
| UterusCorpus | 5.45 | |
| WholeBlood | 3.9 | |
| Wholebrain | 3.2 | |
| colon | 3.6 | |
| pineal_day | 4.48 | |
| pineal_night | 4.38 | |
| retina | 4.325 | |
| small_intestine | 3.45 | |
- Probe name: CUST_15410_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.63 ± 0.76 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.44 ± 0.73 | |
| Basal Part of Pons | 5.79 ± 0.74 | |
| Cerebellar Cortex | 4.56 ± 0.47 | |
| Cerebellar Nuclei | 5.06 ± 0.86 | |
| Claustrum | 5.76 ± 0.63 | |
| Epithalamus | 4.2 ± 0.67 | |
| Frontal Lobe | 5.09 ± 0.61 | |
| Globus Pallidus | 4.84 ± 0.59 | |
| Hypothalamus | 4.48 ± 0.9 | |
| Insula | 5.09 ± 0.36 | |
| Limbic Lobe | 5.37 ± 0.79 | |
| Mesencephalon | 5.22 ± 0.87 | |
| Myelencephalon | 5.38 ± 0.87 | |
| Occipital Lobe | 5.31 ± 0.82 | |
| Parietal Lobe | 5.41 ± 0.68 | |
| Pontine Tegmentum | 5 ± 0.92 | |
| Striatum | 7.51 ± 0.74 | |
| Subthalamus | 5.23 ± 0.25 | |
| Temporal Lobe | 5.25 ± 0.56 | |
| Thalamus | 5.07 ± 0.75 | |
| White Matter | 3.83 ± 0.48 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pde1b | CB | Cerebellum | 4.06 | |
| 4.35 | | |||
| Pde1b | CTX | Cerebral cortex | 16.84 | |
| 12.18 | | |||
| Pde1b | HIP | Hippocampal region | 29.42 | |
| 33.52 | | |||
| Pde1b | HPF | Hippocampal formation | 30.54 | |
| 29.6 | | |||
| Pde1b | HY | Hypothalamus | 13.12 | |
| 8.76 | | |||
| Pde1b | LSX | Lateral septal complex | 16.17 | |
| 11.8 | | |||
| Pde1b | MB | Midbrain | 17.53 | |
| 13.24 | | |||
| Pde1b | MY | Medulla | 18.95 | |
| 17.72 | | |||
| Pde1b | OLF | Olfactory bulb | 49.96 | |
| 30.13 | | |||
| Pde1b | P | Pons | 18.54 | |
| 18.06 | | |||
| Pde1b | PAL | Pallidum | 27.25 | |
| 33.05 | | |||
| Pde1b | RHP | Retrohippocampal region | 32.17 | |
| 22.92 | | |||
| Pde1b | sAMY | Striatum-like amygdalar nuclei | 35.5 | |
| 29.45 | | |||
| Pde1b | STR | Striatum | 100 | |
| 100 | | |||
| Pde1b | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Pde1b | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Pde1b | TH | Thalamus | 18.54 | |
| 13.71 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00075429 | 22 | 160 | 181 | NLDLWCFDVFSLNQAADDHALR | Peptide Atlas |