AutismKB 2.0

Annotation Detail for ZC3HC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZC3HC1 ( 1110054L24Rik,FBXO50,NIPA )
Gene Full Name: zinc finger, C3HC-type containing 1
Band: 7q32.2
Quick LinksEntrez ID:51530; OMIM: NA; Uniprot ID:NIPA_HUMAN; ENSEMBL ID: ENSG00000091732; HGNC ID: 29913
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus17 / 56401230
neonate3 / 3109796
infant2 / 2362084
juvenile2 / 5555635
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor25 / 26384594
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor9 / 9635993
lung tumor8 / 10312777
lymphoma8 / 71755111
non-neoplasia2 / 9725020
normal102 / 336030730
ovarian tumor2 / 7668226
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood5 / 12347840
bone9 / 71655125
bone marrow1 / 4880120
brain41 / 110098937
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus2 / 2020998
eye10 / 21105447
heart4 / 8962644
intestine6 / 23447225
kidney11 / 21177751
larynx0 / 241450 
liver10 / 20774348
lung15 / 33697444
lymph5 / 44270112
lymph node5 / 9161054
mammary gland9 / 15327158
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland2 / 2015599
skin11 / 21057452
spleen2 / 5395237
stomach1 / 9661910
testis31 / 33044293
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7422_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.99 ± 0.74
Basal Forebrain2.77 ± 0.46
Basal Part of Pons2.87 ± 0.68
Cerebellar Cortex3.06 ± 0.58
Cerebellar Nuclei2.76 ± 0.44
Claustrum2.77 ± 0.53
Epithalamus2.62 ± 0.67
Frontal Lobe2.91 ± 0.62
Globus Pallidus2.53 ± 0.84
Hypothalamus3.07 ± 0.6
Insula2.91 ± 0.52
Limbic Lobe2.7 ± 0.63
Mesencephalon2.81 ± 0.66
Myelencephalon2.84 ± 0.6
Occipital Lobe2.59 ± 0.72
Parietal Lobe2.77 ± 0.56
Pontine Tegmentum2.81 ± 0.76
Striatum2.55 ± 0.76
Subthalamus2.71 ± 0.6
Temporal Lobe2.86 ± 0.61
Thalamus2.82 ± 0.59
White Matter2.36 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zc3hc1CBCerebellum7.02
6.63
Zc3hc1CTXCerebral cortex17.34
12.01
Zc3hc1HIPHippocampal region15.11
15.69
Zc3hc1HPFHippocampal formation15.81
14.44
Zc3hc1HYHypothalamus7.46
6.41
Zc3hc1LSXLateral septal complex3.13
2.43
Zc3hc1MBMidbrain6.22
6.34
Zc3hc1MYMedulla14.9
17.35
Zc3hc1OLFOlfactory bulb20.23
14.43
Zc3hc1PPons13.91
17.49
Zc3hc1PALPallidum7.1
5.97
Zc3hc1RHPRetrohippocampal region18.15
13.14
Zc3hc1sAMYStriatum-like amygdalar nuclei5.93
3.88
Zc3hc1STRStriatum5.61
3.94
Zc3hc1STRdStriatum dorsal region3.78
2.6
Zc3hc1STRvStriatum ventral region10.01
6.63
Zc3hc1THThalamus8.55
6.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065501 25 51 75 DTSATSQSVNGSPQAEQPSLESTSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018