AutismKB 2.0

Annotation Detail for RAB6B


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Basic Information Top
Gene Symbol:RAB6B ( - )
Gene Full Name: RAB6B, member RAS oncogene family
Band: 3q22.1
Quick LinksEntrez ID:51560; OMIM: NA; Uniprot ID:RAB6B_HUMAN; ENSEMBL ID: ENSG00000154917; HGNC ID: 14902
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210127_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.85
Adipocyte3.9
AdrenalCortex4.1
Adrenalgland3.3
Amygdala4.15
Appendix3.9
AtrioventricularNode3
BDCA4+_DentriticCells4.45
Bonemarrow3.8
BronchialEpithelialCells3.85
CD105+_Endothelial3.95
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid5.05
CD34+5
CD4+_Tcells4.2
CD56+_NKCells4.75
CD71+_EarlyErythroid44.95
CD8+_Tcells3.75
CardiacMyocytes4.95
Caudatenucleus3.5
Cerebellum3.15
CerebellumPeduncles4.4
CiliaryGanglion2.8
CingulateCortex3.95
Colorectaladenocarcinoma3.95
DorsalRootGanglion3
FetalThyroid3.8
Fetalbrain3.85
Fetalliver3.35
Fetallung3.25
GlobusPallidus2.85
Heart5
Hypothalamus4.3
Kidney3.15
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5.45
Lung4.35
Lymphnode3.35
Lymphoma_burkitts(Daudi)4.95
Lymphoma_burkitts(Raji)5.45
MedullaOblongata3.6
OccipitalLobe3.45
OlfactoryBulb3.1
Ovary2.55
Pancreas3.2
PancreaticIslet4.2
ParietalLobe4.15
Pituitary4.55
Placenta4.1
Pons3.7
PrefrontalCortex4.85
Prostate4.55
Salivarygland3.1
SkeletalMuscle4.55
Skin3.1
SmoothMuscle4.45
Spinalcord4.15
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.35
TemporalLobe3.6
Testis3.35
TestisGermCell3.3
TestisIntersitial3.25
TestisLeydigCell3.85
TestisSeminiferousTubule3.35
Thalamus3.9
Thymus3.1
Thyroid4.9
Tongue3.9
Tonsil3.8
Trachea3.25
TrigeminalGanglion4.05
Uterus3.15
UterusCorpus3.5
WholeBlood4.3
Wholebrain3.85
colon3.9
pineal_day4.86
pineal_night4.76
retina4.75
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P109974
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.02 ± 0.77
Basal Forebrain8.6 ± 0.43
Basal Part of Pons9.85 ± 0.47
Cerebellar Cortex8.71 ± 0.3
Cerebellar Nuclei9 ± 0.89
Claustrum9.03 ± 0.71
Epithalamus7.83 ± 0.66
Frontal Lobe9.32 ± 0.64
Globus Pallidus8.44 ± 0.72
Hypothalamus8.58 ± 0.63
Insula9.5 ± 0.35
Limbic Lobe9.36 ± 0.57
Mesencephalon8.78 ± 0.58
Myelencephalon9.02 ± 0.72
Occipital Lobe9.09 ± 0.68
Parietal Lobe9.34 ± 0.64
Pontine Tegmentum9.07 ± 0.71
Striatum8.29 ± 0.9
Subthalamus8.97 ± 0.17
Temporal Lobe9.48 ± 0.46
Thalamus9.26 ± 0.55
White Matter6.76 ± 0.94
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab6bCBCerebellum100
100
Rab6bCTXCerebral cortex100
100
Rab6bHIPHippocampal region100
100
Rab6bHPFHippocampal formation100
100
Rab6bHYHypothalamus100
100
Rab6bLSXLateral septal complex100
100
Rab6bMBMidbrain100
100
Rab6bMYMedulla100
100
Rab6bOLFOlfactory bulb100
100
Rab6bPPons100
100
Rab6bPALPallidum100
100
Rab6bRHPRetrohippocampal region100
100
Rab6bsAMYStriatum-like amygdalar nuclei100
100
Rab6bSTRStriatum100
100
Rab6bSTRdStriatum dorsal region100
100
Rab6bSTRvStriatum ventral region100
100
Rab6bTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040294 21 33 53 FMYDSFDNTYQATIGIDFLSK Peptide Atlas
RAB6B_HUMAN_115 12 115 126 GSDVIIMLVGNK PRIDE
RAB6B_HUMAN_115 19 115 133 GSDVIIMLVGNKTDLADKR PRIDE
RAB6B_HUMAN_13 13 13 25 FKLVFLGEQSVGK PRIDE
RAB6B_HUMAN_144 14 144 157 AKELSVMFIETSAK PRIDE
RAB6B_HUMAN_146 12 146 157 ELSVMFIETSAK PRIDE
RAB6B_HUMAN_15 11 15 25 LVFLGEQSVGK PRIDE
RAB6B_HUMAN_169 14 169 182 VASALPGMENVQEK PRIDE
RAB6B_HUMAN_63 11 63 73 LQLWDTAGQER PRIDE
RAB6B_HUMAN_84 22 84 105 DSTVAVVVYDITNLNSFQQTSK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018