AutismKB 2.0

Annotation Detail for UFM1


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Basic Information Top
Gene Symbol:UFM1 ( BM-002,C13orf20,bA131P10.1 )
Gene Full Name: ubiquitin-fold modifier 1
Band: 13q13.3
Quick LinksEntrez ID:51569; OMIM: 610553; Uniprot ID:UFM1_HUMAN; ENSEMBL ID: ENSG00000120686; HGNC ID: 20597
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult40 / 193912120
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus23 / 56401240
neonate4 / 31097128
infant1 / 2362042
juvenile1 / 5555617
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal106 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor14 / 26384553
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor8 / 68959116
leukemia7 / 9584273
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia4 / 9725041
normal193 / 336030757
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain30 / 110098927
cervix1 / 4817120
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine7 / 23447229
kidney5 / 21177723
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph1 / 4427022
lymph node4 / 9161043
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate5 / 18934526
salivary gland2 / 2015599
skin9 / 21057442
spleen0 / 539520 
stomach1 / 9661910
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood6 / 12347848
bone3 / 7165541
bone marrow7 / 48801143
brain93 / 110098984
cervix0 / 481710 
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine5 / 23447221
kidney16 / 21177775
larynx0 / 241450 
liver22 / 207743105
lung7 / 33697420
lymph2 / 4427045
lymph node8 / 9161087
mammary gland3 / 15327119
mouth4 / 6705259
muscle5 / 10771546
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta17 / 28082560
prostate12 / 18934563
salivary gland1 / 2015549
skin8 / 21057437
spleen1 / 5395218
stomach1 / 9661910
testis14 / 33044242
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus8 / 23287834
vascular12 / 51780231
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218050_at
Cell line Expression level Expression bar
721_B_lymphoblasts116.35
Adipocyte98.9
AdrenalCortex89.7
Adrenalgland81.55
Amygdala367.45
Appendix86.2
AtrioventricularNode91.3
BDCA4+_DentriticCells234.95
Bonemarrow92.05
BronchialEpithelialCells111.1
CD105+_Endothelial95.35
CD14+_Monocytes129.4
CD19+_BCells(neg._sel.)218.75
CD33+_Myeloid180.85
CD34+224.05
CD4+_Tcells170.35
CD56+_NKCells258.45
CD71+_EarlyErythroid41.65
CD8+_Tcells143.35
CardiacMyocytes146.65
Caudatenucleus88.95
Cerebellum70.1
CerebellumPeduncles87.55
CiliaryGanglion97.75
CingulateCortex97.55
Colorectaladenocarcinoma262
DorsalRootGanglion66.95
FetalThyroid101.65
Fetalbrain170.65
Fetalliver89.7
Fetallung100.1
GlobusPallidus90.75
Heart138.05
Hypothalamus154.15
Kidney60.6
Leukemia_chronicMyelogenousK-56296
Leukemia_promyelocytic-HL-6070.85
Leukemialymphoblastic(MOLT-4)62.55
Liver126.15
Lung112.25
Lymphnode122.55
Lymphoma_burkitts(Daudi)118.25
Lymphoma_burkitts(Raji)174.25
MedullaOblongata76.95
OccipitalLobe94.7
OlfactoryBulb68.05
Ovary92.9
Pancreas95.1
PancreaticIslet164.9
ParietalLobe94.9
Pituitary115.45
Placenta116.45
Pons102.65
PrefrontalCortex157
Prostate132.1
Salivarygland85.1
SkeletalMuscle97.15
Skin81.5
SmoothMuscle144.2
Spinalcord132.4
SubthalamicNucleus63.6
SuperiorCervicalGanglion126.15
TemporalLobe86.45
Testis51.3
TestisGermCell63.2
TestisIntersitial53.5
TestisLeydigCell73.05
TestisSeminiferousTubule64.85
Thalamus94.95
Thymus69.5
Thyroid266.2
Tongue79.9
Tonsil94.05
Trachea101.05
TrigeminalGanglion95.05
Uterus179
UterusCorpus85.2
WholeBlood127.75
Wholebrain85.85
colon174.1
pineal_day131.3
pineal_night123.42
retina138.55
small_intestine173.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P99465
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.63 ± 0.48
Basal Forebrain7.69 ± 0.17
Basal Part of Pons7.36 ± 0.23
Cerebellar Cortex7.37 ± 0.23
Cerebellar Nuclei7.37 ± 0.29
Claustrum7.21 ± 0.49
Epithalamus7.56 ± 0.15
Frontal Lobe7.57 ± 0.26
Globus Pallidus7.88 ± 0.23
Hypothalamus7.76 ± 0.25
Insula7.72 ± 0.16
Limbic Lobe7.6 ± 0.41
Mesencephalon7.51 ± 0.27
Myelencephalon7.5 ± 0.33
Occipital Lobe7.33 ± 0.38
Parietal Lobe7.45 ± 0.29
Pontine Tegmentum7.65 ± 0.32
Striatum7.37 ± 0.26
Subthalamus7.48 ± 0.18
Temporal Lobe7.67 ± 0.22
Thalamus7.35 ± 0.23
White Matter8.23 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ufm1CBCerebellum21.2
33.34
Ufm1CTXCerebral cortex35.69
29.8
Ufm1HIPHippocampal region31.11
42.82
Ufm1HPFHippocampal formation32.58
36.88
Ufm1HYHypothalamus8.3
7.12
Ufm1LSXLateral septal complex31
24.25
Ufm1MBMidbrain15.79
16.05
Ufm1MYMedulla23.71
30.19
Ufm1OLFOlfactory bulb23.72
18.33
Ufm1PPons21.8
25.44
Ufm1PALPallidum13.88
14.16
Ufm1RHPRetrohippocampal region35.87
31.27
Ufm1sAMYStriatum-like amygdalar nuclei7.54
6.36
Ufm1STRStriatum9.91
8.3
Ufm1STRdStriatum dorsal region8.54
7.52
Ufm1STRvStriatum ventral region8.72
6.79
Ufm1THThalamus20.6
18.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136031 15 20 34 VLSVPESTPFTAVLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018