AutismKB 2.0

Annotation Detail for PDGFRL


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Basic Information Top
Gene Symbol:PDGFRL ( PDGRL,PRLTS )
Gene Full Name: platelet-derived growth factor receptor-like
Band: 8p22
Quick LinksEntrez ID:5157; OMIM: 604584; Uniprot ID:PGFRL_HUMAN; ENSEMBL ID: ENSG00000104213; HGNC ID: 8805
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal62 / 336030718
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone6 / 7165583
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue4 / 14925526
ear3 / 16212185
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta13 / 28082546
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205226_at
Cell line Expression level Expression bar
721_B_lymphoblasts70.95
Adipocyte39.4
AdrenalCortex5.25
Adrenalgland4.15
Amygdala5.05
Appendix5.35
AtrioventricularNode19.05
BDCA4+_DentriticCells5.2
Bonemarrow4.9
BronchialEpithelialCells4.7
CD105+_Endothelial4.9
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)5.1
CD33+_Myeloid6.15
CD34+6.05
CD4+_Tcells5.2
CD56+_NKCells5.55
CD71+_EarlyErythroid4.55
CD8+_Tcells4.5
CardiacMyocytes6.5
Caudatenucleus4.55
Cerebellum3.95
CerebellumPeduncles5.55
CiliaryGanglion31.65
CingulateCortex4.95
Colorectaladenocarcinoma4.85
DorsalRootGanglion4.8
FetalThyroid168.5
Fetalbrain4.75
Fetalliver4.25
Fetallung4.55
GlobusPallidus3.6
Heart6.45
Hypothalamus5.3
Kidney4.1
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.9
Liver6.5
Lung5.3
Lymphnode4.2
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)6.95
MedullaOblongata4.35
OccipitalLobe4.3
OlfactoryBulb16.7
Ovary9.1
Pancreas3.95
PancreaticIslet7.95
ParietalLobe5.2
Pituitary6.9
Placenta11.25
Pons4.6
PrefrontalCortex5.9
Prostate5.65
Salivarygland5.1
SkeletalMuscle6.05
Skin5.55
SmoothMuscle83.05
Spinalcord5.15
SubthalamicNucleus4.5
SuperiorCervicalGanglion24.9
TemporalLobe4.5
Testis9.9
TestisGermCell13.6
TestisIntersitial4.1
TestisLeydigCell5.5
TestisSeminiferousTubule4.25
Thalamus5
Thymus5.5
Thyroid79
Tongue10
Tonsil4.7
Trachea23.3
TrigeminalGanglion6.4
Uterus7.25
UterusCorpus4.5
WholeBlood5.2
Wholebrain4
colon4.9
pineal_day6.04
pineal_night5.86
retina6.55
small_intestine4.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_883_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.65 ± 0.94
Basal Forebrain2.35 ± 0.27
Basal Part of Pons2.27 ± 0.67
Cerebellar Cortex2.58 ± 0.68
Cerebellar Nuclei2.62 ± 0.66
Claustrum2.85 ± 0.74
Epithalamus2.22 ± 0.94
Frontal Lobe2.47 ± 0.68
Globus Pallidus2.15 ± 0.64
Hypothalamus2.31 ± 0.6
Insula2.34 ± 0.74
Limbic Lobe2.39 ± 0.72
Mesencephalon2.54 ± 0.69
Myelencephalon2.46 ± 0.68
Occipital Lobe2.18 ± 0.74
Parietal Lobe2.25 ± 0.72
Pontine Tegmentum2.44 ± 0.79
Striatum2.89 ± 0.8
Subthalamus2.64 ± 0.76
Temporal Lobe2.42 ± 0.73
Thalamus2.58 ± 0.57
White Matter3.53 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PdgfrlCBCerebellum2.21
2.64
PdgfrlCTXCerebral cortex1.69
1.19
PdgfrlHIPHippocampal region0.67
0.72
PdgfrlHPFHippocampal formation0.84
0.78
PdgfrlHYHypothalamus1.4
1.09
PdgfrlLSXLateral septal complex0.56
0.67
PdgfrlMBMidbrain1.93
1.86
PdgfrlMYMedulla7.84
8.6
PdgfrlOLFOlfactory bulb12.21
10.22
PdgfrlPPons7.37
8.4
PdgfrlPALPallidum6.19
5.83
PdgfrlRHPRetrohippocampal region1.13
0.86
PdgfrlsAMYStriatum-like amygdalar nuclei3.25
2.02
PdgfrlSTRStriatum1.76
1.25
PdgfrlSTRdStriatum dorsal region1.04
0.75
PdgfrlSTRvStriatum ventral region4.86
3.25
PdgfrlTHThalamus2.31
1.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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