AutismKB 2.0

Annotation Detail for AZIN1


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Basic Information Top
Gene Symbol:AZIN1 ( MGC3832,MGC691,OAZI,OAZIN,ODC1L )
Gene Full Name: antizyme inhibitor 1
Band: 8q22.3
Quick LinksEntrez ID:51582; OMIM: 607909; Uniprot ID:AZIN1_HUMAN; ENSEMBL ID: ENSG00000155096; HGNC ID: 16432
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst26 / 62319417
fetus273 / 564012484
neonate13 / 31097418
infant4 / 23620169
juvenile15 / 55556269
adult365 / 1939121188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma2 / 17475114
breast (mammary gland) tumor8 / 9417884
cervical tumor7 / 34366203
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor3 / 17290173
gastrointestinal tumor11 / 11936992
germ cell tumor119 / 263845451
glioma8 / 10688374
head and neck tumor53 / 136302388
kidney tumor14 / 68959203
leukemia9 / 9584293
liver tumor8 / 9635983
lung tumor6 / 10312758
lymphoma4 / 7175555
non-neoplasia12 / 97250123
normal1150 / 3360307342
ovarian tumor16 / 76682208
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer15 / 102680146
retinoblastoma2 / 4635643
skin tumor10 / 12494980
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor26 / 90257288
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland11 / 33197331
ascites6 / 40015149
bladder8 / 29757268
blood21 / 123478170
bone2 / 7165527
bone marrow5 / 48801102
brain598 / 1100989543
cervix7 / 48171145
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue61 / 215722282
esophagus3 / 20209148
eye17 / 21105480
heart13 / 89626145
intestine25 / 234472106
kidney69 / 211777325
larynx2 / 2414582
liver21 / 207743101
lung47 / 336974139
lymph1 / 4427022
lymph node35 / 91610382
mammary gland9 / 15327158
mouth49 / 67052730
muscle25 / 107715232
nerve2 / 15768126
ovary17 / 102051166
pancreas24 / 214812111
parathyroid1 / 2053948
pharynx4 / 4132896
pituitary gland2 / 16585120
placenta114 / 280825405
prostate34 / 189345179
salivary gland3 / 20155148
skin35 / 210574166
spleen12 / 53952222
stomach6 / 9661962
testis138 / 330442417
thymus50 / 81131616
thyroid7 / 47473147
tonsil0 / 169990 
trachea107 / 524132041
umbilical cord0 / 136800 
uterus74 / 232878317
vascular21 / 51780405
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201772_at
Cell line Expression level Expression bar
721_B_lymphoblasts134.65
Adipocyte23.55
AdrenalCortex5.7
Adrenalgland23.95
Amygdala82.95
Appendix5.75
AtrioventricularNode9.75
BDCA4+_DentriticCells111.9
Bonemarrow35.6
BronchialEpithelialCells59.95
CD105+_Endothelial55.75
CD14+_Monocytes39.6
CD19+_BCells(neg._sel.)38.3
CD33+_Myeloid81.4
CD34+44.4
CD4+_Tcells29.95
CD56+_NKCells60.55
CD71+_EarlyErythroid53.1
CD8+_Tcells24
CardiacMyocytes19
Caudatenucleus10.45
Cerebellum29.2
CerebellumPeduncles13.85
CiliaryGanglion5.75
CingulateCortex12.7
Colorectaladenocarcinoma42.1
DorsalRootGanglion8.3
FetalThyroid6.6
Fetalbrain49.45
Fetalliver25.5
Fetallung24.75
GlobusPallidus14
Heart10.5
Hypothalamus27.4
Kidney9.4
Leukemia_chronicMyelogenousK-56221.45
Leukemia_promyelocytic-HL-6042.25
Leukemialymphoblastic(MOLT-4)29.2
Liver6.45
Lung17.35
Lymphnode14.2
Lymphoma_burkitts(Daudi)26.9
Lymphoma_burkitts(Raji)49.05
MedullaOblongata13.55
OccipitalLobe33.2
OlfactoryBulb22.5
Ovary5.25
Pancreas24.1
PancreaticIslet31.75
ParietalLobe14.55
Pituitary48.5
Placenta397.35
Pons9.05
PrefrontalCortex48.65
Prostate33.4
Salivarygland8.95
SkeletalMuscle5.75
Skin6.85
SmoothMuscle21.95
Spinalcord33.55
SubthalamicNucleus17.5
SuperiorCervicalGanglion10.05
TemporalLobe10.15
Testis17.95
TestisGermCell13.45
TestisIntersitial9.3
TestisLeydigCell6
TestisSeminiferousTubule6.9
Thalamus11
Thymus33.2
Thyroid38.7
Tongue4.9
Tonsil14.75
Trachea32.9
TrigeminalGanglion11.8
Uterus19.65
UterusCorpus6.6
WholeBlood50.95
Wholebrain43.9
colon56.25
pineal_day69.2
pineal_night70.1
retina53.55
small_intestine94.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P183301
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.1 ± 1.1
Basal Forebrain2.66 ± 0.29
Basal Part of Pons2.4 ± 0.37
Cerebellar Cortex2.57 ± 0.77
Cerebellar Nuclei2.86 ± 0.69
Claustrum3.41 ± 0.68
Epithalamus2.28 ± 0.73
Frontal Lobe2.79 ± 0.77
Globus Pallidus3.07 ± 0.6
Hypothalamus2.65 ± 0.74
Insula2.69 ± 0.62
Limbic Lobe2.85 ± 0.75
Mesencephalon2.9 ± 0.67
Myelencephalon2.82 ± 0.75
Occipital Lobe2.59 ± 0.75
Parietal Lobe2.73 ± 0.69
Pontine Tegmentum2.73 ± 0.69
Striatum2.63 ± 0.74
Subthalamus3.01 ± 0.52
Temporal Lobe2.81 ± 0.73
Thalamus2.68 ± 0.65
White Matter2.65 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Azin1CBCerebellum28.81
50.12
Azin1CTXCerebral cortex83.5
82.95
Azin1HIPHippocampal region46.72
88.83
Azin1HPFHippocampal formation54.05
83.14
Azin1HYHypothalamus16.19
16.6
Azin1LSXLateral septal complex14.69
12.07
Azin1MBMidbrain21.84
26.74
Azin1MYMedulla30.8
52.25
Azin1OLFOlfactory bulb86.75
96.8
Azin1PPons28.69
42.13
Azin1PALPallidum25.33
31.33
Azin1RHPRetrohippocampal region65.4
71.35
Azin1sAMYStriatum-like amygdalar nuclei25.08
25.05
Azin1STRStriatum21.3
19.73
Azin1STRdStriatum dorsal region14.82
13.72
Azin1STRvStriatum ventral region44.15
37.56
Azin1THThalamus32.09
33.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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