AutismKB 2.0

Annotation Detail for PIAS4


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Basic Information Top
Gene Symbol:PIAS4 ( FLJ12419,MGC35296,PIASY,Piasg,ZMIZ6 )
Gene Full Name: protein inhibitor of activated STAT, 4
Band: 19p13.3
Quick LinksEntrez ID:51588; OMIM: 605989; Uniprot ID:PIAS4_HUMAN; ENSEMBL ID: ENSG00000105229; HGNC ID: 17002
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult46 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor8 / 26384530
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal92 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain33 / 110098929
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine9 / 23447238
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate9 / 18934547
salivary gland0 / 201550 
skin4 / 21057418
spleen2 / 5395237
stomach2 / 9661920
testis11 / 33044233
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212881_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte3.65
AdrenalCortex4.05
Adrenalgland3.1
Amygdala3.95
Appendix3.65
AtrioventricularNode3.8
BDCA4+_DentriticCells4.5
Bonemarrow3.65
BronchialEpithelialCells3.55
CD105+_Endothelial3.8
CD14+_Monocytes4.05
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid4.5
CD34+4.85
CD4+_Tcells4.15
CD56+_NKCells4.6
CD71+_EarlyErythroid3.85
CD8+_Tcells3.75
CardiacMyocytes4.65
Caudatenucleus3.35
Cerebellum4.3
CerebellumPeduncles4.4
CiliaryGanglion3.25
CingulateCortex3.95
Colorectaladenocarcinoma3.75
DorsalRootGanglion3.35
FetalThyroid3.6
Fetalbrain4.2
Fetalliver3.2
Fetallung2.95
GlobusPallidus2.7
Heart4.65
Hypothalamus4.3
Kidney3.2
Leukemia_chronicMyelogenousK-5623.4
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)3.05
Liver4.9
Lung4.95
Lymphnode3.2
Lymphoma_burkitts(Daudi)4.75
Lymphoma_burkitts(Raji)5.15
MedullaOblongata3.4
OccipitalLobe3.45
OlfactoryBulb2.95
Ovary2.45
Pancreas3.2
PancreaticIslet4.3
ParietalLobe3.95
Pituitary4.35
Placenta3.95
Pons3.65
PrefrontalCortex4.95
Prostate7.1
Salivarygland3
SkeletalMuscle4.55
Skin3.3
SmoothMuscle4.25
Spinalcord3.9
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.5
TemporalLobe3.35
Testis5.25
TestisGermCell3.35
TestisIntersitial3.45
TestisLeydigCell3.8
TestisSeminiferousTubule4
Thalamus3.8
Thymus3.6
Thyroid4.8
Tongue3.9
Tonsil3.65
Trachea3.05
TrigeminalGanglion5.1
Uterus3.45
UterusCorpus3.3
WholeBlood4.15
Wholebrain7.6
colon3.7
pineal_day4.74
pineal_night4.72
retina4.675
small_intestine3.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5659_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.79 ± 0.88
Basal Forebrain2.33 ± 0.26
Basal Part of Pons2.56 ± 0.64
Cerebellar Cortex3.1 ± 0.42
Cerebellar Nuclei2.82 ± 0.49
Claustrum2.89 ± 0.64
Epithalamus2.5 ± 0.65
Frontal Lobe2.65 ± 0.59
Globus Pallidus2.69 ± 0.91
Hypothalamus2.48 ± 0.65
Insula2.36 ± 0.55
Limbic Lobe2.58 ± 0.58
Mesencephalon2.65 ± 0.62
Myelencephalon2.62 ± 0.65
Occipital Lobe2.41 ± 0.8
Parietal Lobe2.52 ± 0.53
Pontine Tegmentum2.6 ± 0.65
Striatum2.24 ± 0.67
Subthalamus2.65 ± 0.89
Temporal Lobe2.61 ± 0.71
Thalamus2.6 ± 0.59
White Matter3.21 ± 0.38
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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