AutismKB 2.0

Annotation Detail for NOP58


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Basic Information Top
Gene Symbol:NOP58 ( NOP5,NOP5/NOP58 )
Gene Full Name: NOP58 ribonucleoprotein homolog (yeast)
Band: 2q33.1
Quick LinksEntrez ID:51602; OMIM: NA; Uniprot ID:NOP58_HUMAN; ENSEMBL ID: ENSG00000055044; HGNC ID: 29926
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst11 / 62319176
fetus29 / 56401251
neonate0 / 310970 
infant4 / 23620169
juvenile2 / 5555635
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma11 / 82823132
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor18 / 26384568
glioma9 / 10688384
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia13 / 95842135
liver tumor4 / 9635941
lung tumor4 / 10312738
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal148 / 336030744
ovarian tumor8 / 76682104
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer10 / 10268097
retinoblastoma8 / 46356172
skin tumor19 / 124949152
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood16 / 123478129
bone12 / 71655167
bone marrow10 / 48801204
brain40 / 110098936
cervix3 / 4817162
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue30 / 215722139
esophagus1 / 2020949
eye12 / 21105456
heart2 / 8962622
intestine15 / 23447263
kidney15 / 21177770
larynx0 / 241450 
liver11 / 20774352
lung21 / 33697462
lymph4 / 4427090
lymph node5 / 9161054
mammary gland5 / 15327132
mouth4 / 6705259
muscle8 / 10771574
nerve0 / 157680 
ovary10 / 10205197
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta19 / 28082567
prostate11 / 18934558
salivary gland0 / 201550 
skin23 / 210574109
spleen0 / 539520 
stomach6 / 9661962
testis3 / 3304429
thymus1 / 8113112
thyroid3 / 4747363
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9620_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.04 ± 0.36
Basal Forebrain5.65 ± 0.26
Basal Part of Pons5.78 ± 0.38
Cerebellar Cortex5.93 ± 0.39
Cerebellar Nuclei5.47 ± 0.35
Claustrum6 ± 0.31
Epithalamus5.6 ± 0.51
Frontal Lobe5.73 ± 0.43
Globus Pallidus5.58 ± 0.49
Hypothalamus5.58 ± 0.36
Insula5.77 ± 0.38
Limbic Lobe5.92 ± 0.4
Mesencephalon5.77 ± 0.37
Myelencephalon5.72 ± 0.42
Occipital Lobe5.97 ± 0.42
Parietal Lobe5.76 ± 0.41
Pontine Tegmentum5.7 ± 0.42
Striatum5.69 ± 0.57
Subthalamus5.78 ± 0.16
Temporal Lobe5.71 ± 0.41
Thalamus5.66 ± 0.37
White Matter5.69 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nol5CBCerebellum18.55
22.16
Nol5CTXCerebral cortex30.35
22.93
Nol5HIPHippocampal region33.59
55.15
Nol5HPFHippocampal formation28.36
37.68
Nol5HYHypothalamus12.66
9.97
Nol5LSXLateral septal complex16.7
12.1
Nol5MBMidbrain15.57
13.7
Nol5MYMedulla17.01
16.3
Nol5OLFOlfactory bulb19.25
15.56
Nol5PPons10.07
9.66
Nol5PALPallidum9.81
8.43
Nol5RHPRetrohippocampal region20.2
16.17
Nol5sAMYStriatum-like amygdalar nuclei8.03
5.76
Nol5STRStriatum8.4
6.18
Nol5STRdStriatum dorsal region7.1
5.5
Nol5STRvStriatum ventral region10.03
6.55
Nol5THThalamus9.75
8.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NOP58_HUMAN_279 19 279 297 MMAIAPNVTVMVGELVGAR PRIDE
NOP58_HUMAN_495 23 495 517 HIKEEPLSEEEPCTSTAIASPEK PRIDE
PAp00002107 18 100 117 EKLNLSCIHSPVVNELMR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018