AutismKB 2.0

Annotation Detail for METTL13


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Basic Information Top
Gene Symbol:METTL13 ( 5630401D24Rik,FLJ10310,KIAA0859,feat )
Gene Full Name: methyltransferase like 13
Band: 1q24.3
Quick LinksEntrez ID:51603; OMIM: NA; Uniprot ID:MTL13_HUMAN; ENSEMBL ID: ENSG00000010165; HGNC ID: 24248
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst10 / 62319160
fetus57 / 564012101
neonate6 / 31097192
infant6 / 23620254
juvenile14 / 55556251
adult174 / 193912189
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor14 / 94178148
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor17 / 119369142
germ cell tumor74 / 263845280
glioma12 / 106883112
head and neck tumor13 / 13630295
kidney tumor4 / 6895958
leukemia10 / 95842104
liver tumor16 / 96359166
lung tumor6 / 10312758
lymphoma5 / 7175569
non-neoplasia4 / 9725041
normal268 / 336030779
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS32 / 125680254
prostate cancer7 / 10268068
retinoblastoma7 / 46356151
skin tumor23 / 124949184
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites13 / 40015324
bladder2 / 2975767
blood14 / 123478113
bone4 / 7165555
bone marrow3 / 4880161
brain121 / 1100989109
cervix7 / 48171145
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue23 / 215722106
esophagus1 / 2020949
eye15 / 21105471
heart12 / 89626133
intestine20 / 23447285
kidney14 / 21177766
larynx0 / 241450 
liver19 / 20774391
lung27 / 33697480
lymph1 / 4427022
lymph node3 / 9161032
mammary gland15 / 15327197
mouth15 / 67052223
muscle4 / 10771537
nerve1 / 1576863
ovary10 / 10205197
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate12 / 18934563
salivary gland0 / 201550 
skin34 / 210574161
spleen9 / 53952166
stomach2 / 9661920
testis59 / 330442178
thymus6 / 8113173
thyroid0 / 474730 
tonsil1 / 1699958
trachea12 / 52413228
umbilical cord1 / 1368073
uterus22 / 23287894
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212407_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.85
Adipocyte5
AdrenalCortex5.3
Adrenalgland4.25
Amygdala6.1
Appendix5.25
AtrioventricularNode3.85
BDCA4+_DentriticCells23.95
Bonemarrow5.1
BronchialEpithelialCells5.5
CD105+_Endothelial131.7
CD14+_Monocytes9.15
CD19+_BCells(neg._sel.)17.75
CD33+_Myeloid10.8
CD34+28.25
CD4+_Tcells11.35
CD56+_NKCells14
CD71+_EarlyErythroid9.5
CD8+_Tcells10.65
CardiacMyocytes7.3
Caudatenucleus5.3
Cerebellum7.45
CerebellumPeduncles6.35
CiliaryGanglion3.6
CingulateCortex5.2
Colorectaladenocarcinoma5.05
DorsalRootGanglion4.1
FetalThyroid4.85
Fetalbrain5.05
Fetalliver4.75
Fetallung4.05
GlobusPallidus3.7
Heart6.4
Hypothalamus7.1
Kidney3.95
Leukemia_chronicMyelogenousK-5626.8
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)4.4
Liver6.7
Lung7.4
Lymphnode5.35
Lymphoma_burkitts(Daudi)7.15
Lymphoma_burkitts(Raji)7.4
MedullaOblongata4.6
OccipitalLobe4.6
OlfactoryBulb4.1
Ovary3.3
Pancreas4.05
PancreaticIslet6
ParietalLobe5.5
Pituitary5.85
Placenta5.35
Pons4.85
PrefrontalCortex6.25
Prostate5.7
Salivarygland4.6
SkeletalMuscle5.95
Skin4.05
SmoothMuscle5.75
Spinalcord6.1
SubthalamicNucleus4.85
SuperiorCervicalGanglion5.7
TemporalLobe4.6
Testis7.65
TestisGermCell9.45
TestisIntersitial4.3
TestisLeydigCell5
TestisSeminiferousTubule4.35
Thalamus5.5
Thymus5.2
Thyroid6.4
Tongue4.8
Tonsil4.95
Trachea4.85
TrigeminalGanglion5
Uterus4.2
UterusCorpus4.7
WholeBlood8.85
Wholebrain7.45
colon5.1
pineal_day7.24
pineal_night6.32
retina6.275
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P201676
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.73
Basal Forebrain4.61 ± 0.23
Basal Part of Pons5.22 ± 0.4
Cerebellar Cortex5.04 ± 0.32
Cerebellar Nuclei5.04 ± 0.55
Claustrum4.45 ± 0.81
Epithalamus4.83 ± 0.56
Frontal Lobe4.89 ± 0.42
Globus Pallidus4.58 ± 0.34
Hypothalamus4.75 ± 0.38
Insula4.82 ± 0.42
Limbic Lobe4.62 ± 0.61
Mesencephalon4.71 ± 0.55
Myelencephalon4.69 ± 0.49
Occipital Lobe4.31 ± 0.53
Parietal Lobe4.69 ± 0.52
Pontine Tegmentum4.65 ± 0.51
Striatum4.31 ± 0.5
Subthalamus4.42 ± 0.82
Temporal Lobe4.83 ± 0.4
Thalamus4.69 ± 0.48
White Matter5.05 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5630401D24RikCBCerebellum5.61
5.53
5630401D24RikCTXCerebral cortex12.5
8.77
5630401D24RikHIPHippocampal region7.02
6.65
5630401D24RikHPFHippocampal formation6.47
5.61
5630401D24RikHYHypothalamus0.83
0.7
5630401D24RikLSXLateral septal complex0.51
0.39
5630401D24RikMBMidbrain3.51
3.51
5630401D24RikMYMedulla1.78
2.25
5630401D24RikOLFOlfactory bulb7.18
5.76
5630401D24RikPPons3.6
3.95
5630401D24RikPALPallidum1.07
0.91
5630401D24RikRHPRetrohippocampal region5.72
4.35
5630401D24RiksAMYStriatum-like amygdalar nuclei3.68
2.63
5630401D24RikSTRStriatum7.83
5.36
5630401D24RikSTRdStriatum dorsal region11.07
7.68
5630401D24RikSTRvStriatum ventral region2.54
1.67
5630401D24RikTHThalamus3.08
2.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MTL13_HUMAN_1 9 1 9 MNLLPKSSR PRIDE
PAp00027521 19 641 659 RIEGEVNEILFCQLHPEQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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