AutismKB 2.0

Annotation Detail for STYXL1


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Basic Information Top
Gene Symbol:STYXL1 ( DUSP24,MK-STYX )
Gene Full Name: serine/threonine/tyrosine interacting-like 1
Band: 7q11.23
Quick LinksEntrez ID:51657; OMIM: NA; Uniprot ID:STYL1_HUMAN; ENSEMBL ID: ENSG00000127952; HGNC ID: 18165
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst1 / 6231916
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma14 / 106883130
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor10 / 10312796
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal123 / 336030736
ovarian tumor29 / 76682378
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone6 / 7165583
bone marrow4 / 4880181
brain35 / 110098931
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye12 / 21105456
heart4 / 8962644
intestine11 / 23447246
kidney12 / 21177756
larynx0 / 241450 
liver8 / 20774338
lung22 / 33697465
lymph1 / 4427022
lymph node3 / 9161032
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary29 / 102051284
pancreas14 / 21481265
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta10 / 28082535
prostate6 / 18934531
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218321_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts114.35
Adipocyte85.95
AdrenalCortex89.85
Adrenalgland79.7
Amygdala88.15
Appendix87.15
AtrioventricularNode65.6
BDCA4+_DentriticCells101.1
Bonemarrow88.05
BronchialEpithelialCells120.15
CD105+_Endothelial86.7
CD14+_Monocytes196
CD19+_BCells(neg._sel.)94.3
CD33+_Myeloid110.8
CD34+99.3
CD4+_Tcells83.5
CD56+_NKCells108.3
CD71+_EarlyErythroid60.25
CD8+_Tcells74.3
CardiacMyocytes107.7
Caudatenucleus78.65
Cerebellum71.6
CerebellumPeduncles98.4
CiliaryGanglion60.85
CingulateCortex89.85
Colorectaladenocarcinoma96.5
DorsalRootGanglion65.1
FetalThyroid83
Fetalbrain85.6
Fetalliver75.65
Fetallung73.85
GlobusPallidus62.95
Heart113.4
Hypothalamus97.6
Kidney70.3
Leukemia_chronicMyelogenousK-562136.7
Leukemia_promyelocytic-HL-6076
Leukemialymphoblastic(MOLT-4)66.7
Liver137.05
Lung94.2
Lymphnode76.2
Lymphoma_burkitts(Daudi)116.6
Lymphoma_burkitts(Raji)120.45
MedullaOblongata81.45
OccipitalLobe79.2
OlfactoryBulb69.1
Ovary57.55
Pancreas70.5
PancreaticIslet125.8
ParietalLobe92.5
Pituitary115.75
Placenta97.45
Pons82.65
PrefrontalCortex127.5
Prostate101.2
Salivarygland69.75
SkeletalMuscle99.1
Skin65.25
SmoothMuscle114.65
Spinalcord95.3
SubthalamicNucleus79.35
SuperiorCervicalGanglion99.2
TemporalLobe79.4
Testis161.35
TestisGermCell103.05
TestisIntersitial103.7
TestisLeydigCell89.05
TestisSeminiferousTubule90.3
Thalamus89
Thymus77.05
Thyroid103.9
Tongue84.2
Tonsil85.45
Trachea74.3
TrigeminalGanglion84.15
Uterus70.35
UterusCorpus75.95
WholeBlood100.75
Wholebrain76.9
colon89.65
pineal_day108.92
pineal_night103.88
retina104.625
small_intestine88.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5757_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.85 ± 0.37
Basal Forebrain5.82 ± 0.19
Basal Part of Pons5.9 ± 0.26
Cerebellar Cortex5.71 ± 0.21
Cerebellar Nuclei5.68 ± 0.51
Claustrum6.25 ± 0.59
Epithalamus6.4 ± 0.44
Frontal Lobe5.83 ± 0.38
Globus Pallidus6.51 ± 0.29
Hypothalamus5.62 ± 0.41
Insula5.9 ± 0.48
Limbic Lobe6.21 ± 0.39
Mesencephalon5.76 ± 0.5
Myelencephalon5.95 ± 0.45
Occipital Lobe6.25 ± 0.47
Parietal Lobe5.88 ± 0.41
Pontine Tegmentum5.96 ± 0.41
Striatum6.51 ± 0.37
Subthalamus5.51 ± 0.4
Temporal Lobe5.88 ± 0.31
Thalamus5.89 ± 0.31
White Matter7.02 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Styxl1CBCerebellum6.92
6.98
Styxl1CTXCerebral cortex8.35
6.01
Styxl1HIPHippocampal region7.7
7.69
Styxl1HPFHippocampal formation7.3
6.74
Styxl1HYHypothalamus18.83
14.82
Styxl1LSXLateral septal complex1.93
1.86
Styxl1MBMidbrain10.01
9.69
Styxl1MYMedulla18.47
21.18
Styxl1OLFOlfactory bulb25.86
20.33
Styxl1PPons21.84
24.31
Styxl1PALPallidum12.43
9.96
Styxl1RHPRetrohippocampal region6.16
4.73
Styxl1sAMYStriatum-like amygdalar nuclei3.13
5.34
Styxl1STRStriatum6.2
4.67
Styxl1STRdStriatum dorsal region3.63
2.64
Styxl1STRvStriatum ventral region18.92
12.11
Styxl1THThalamus13.45
10.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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