AutismKB 2.0

Annotation Detail for ASB1


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Basic Information Top
Gene Symbol:ASB1 ( ASB-1,KIAA1146,MGC11165 )
Gene Full Name: ankyrin repeat and SOCS box-containing 1
Band: 2q37.3
Quick LinksEntrez ID:51665; OMIM: 605758; Uniprot ID:ASB1_HUMAN; ENSEMBL ID: ENSG00000065802; HGNC ID: 16011
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor11 / 26384541
glioma7 / 10688365
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal131 / 336030738
ovarian tumor3 / 7668239
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor4 / 12494932
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood2 / 12347816
bone5 / 7165569
bone marrow0 / 488010 
brain35 / 110098931
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye9 / 21105442
heart2 / 8962622
intestine13 / 23447255
kidney9 / 21177742
larynx3 / 24145124
liver9 / 20774343
lung11 / 33697432
lymph0 / 442700 
lymph node11 / 91610120
mammary gland3 / 15327119
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate8 / 18934542
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach1 / 9661910
testis21 / 33044263
thymus2 / 8113124
thyroid6 / 47473126
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212819_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.95
Adipocyte13.15
AdrenalCortex18.55
Adrenalgland12.35
Amygdala17.25
Appendix16.8
AtrioventricularNode18.85
BDCA4+_DentriticCells12.9
Bonemarrow15.35
BronchialEpithelialCells12.65
CD105+_Endothelial13.6
CD14+_Monocytes14.6
CD19+_BCells(neg._sel.)13.8
CD33+_Myeloid16.45
CD34+15.55
CD4+_Tcells15.9
CD56+_NKCells17.55
CD71+_EarlyErythroid14.8
CD8+_Tcells20.1
CardiacMyocytes29.75
Caudatenucleus12.55
Cerebellum11.35
CerebellumPeduncles19.25
CiliaryGanglion18.25
CingulateCortex14.95
Colorectaladenocarcinoma13.6
DorsalRootGanglion12.7
FetalThyroid20.2
Fetalbrain13.15
Fetalliver12.45
Fetallung9.8
GlobusPallidus15.25
Heart26.5
Hypothalamus14.65
Kidney12.5
Leukemia_chronicMyelogenousK-56212.2
Leukemia_promyelocytic-HL-6011.2
Leukemialymphoblastic(MOLT-4)10.6
Liver20.95
Lung14.4
Lymphnode10.9
Lymphoma_burkitts(Daudi)18
Lymphoma_burkitts(Raji)22.5
MedullaOblongata11.85
OccipitalLobe13.25
OlfactoryBulb10.55
Ovary10.8
Pancreas11.3
PancreaticIslet18.3
ParietalLobe16.1
Pituitary15.65
Placenta12
Pons15.1
PrefrontalCortex22
Prostate15.05
Salivarygland11.35
SkeletalMuscle22.6
Skin17.25
SmoothMuscle15.85
Spinalcord14.6
SubthalamicNucleus21.25
SuperiorCervicalGanglion20.4
TemporalLobe12.7
Testis10.95
TestisGermCell10.4
TestisIntersitial12.25
TestisLeydigCell14.15
TestisSeminiferousTubule11.45
Thalamus15.75
Thymus8.9
Thyroid17.75
Tongue18.3
Tonsil13.55
Trachea10.65
TrigeminalGanglion52.35
Uterus14.6
UterusCorpus13.8
WholeBlood13.6
Wholebrain13.05
colon13.5
pineal_day16.7
pineal_night16.74
retina17.4
small_intestine12.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P165360
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.54 ± 0.38
Basal Forebrain6.07 ± 0.22
Basal Part of Pons5.71 ± 0.22
Cerebellar Cortex5.58 ± 0.24
Cerebellar Nuclei5.53 ± 0.49
Claustrum5.51 ± 0.53
Epithalamus5.92 ± 0.42
Frontal Lobe5.86 ± 0.33
Globus Pallidus6.08 ± 0.25
Hypothalamus5.84 ± 0.34
Insula5.71 ± 0.29
Limbic Lobe5.91 ± 0.31
Mesencephalon5.83 ± 0.4
Myelencephalon5.82 ± 0.38
Occipital Lobe5.54 ± 0.3
Parietal Lobe5.73 ± 0.32
Pontine Tegmentum5.74 ± 0.39
Striatum6.09 ± 0.32
Subthalamus5.95 ± 0.2
Temporal Lobe5.85 ± 0.33
Thalamus5.73 ± 0.33
White Matter6.23 ± 0.21
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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