AutismKB 2.0

Annotation Detail for ENPP3


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Basic Information Top
Gene Symbol:ENPP3 ( B10,CD203c,NPP3,PD-IBETA,PDNP3 )
Gene Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Band: 6q23.2
Quick LinksEntrez ID:5169; OMIM: 602182; Uniprot ID:ENPP3_HUMAN; ENSEMBL ID: ENSG00000154269; HGNC ID: 3358
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal32 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis2 / 3304426
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7669_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.11 ± 0.97
Basal Forebrain1.68 ± 0.2
Basal Part of Pons1.39 ± 0.4
Cerebellar Cortex2.06 ± 0.55
Cerebellar Nuclei1.95 ± 0.69
Claustrum2.6 ± 0.82
Epithalamus1.38 ± 0.65
Frontal Lobe1.47 ± 0.58
Globus Pallidus2.01 ± 0.45
Hypothalamus1.71 ± 0.64
Insula1.54 ± 0.49
Limbic Lobe1.69 ± 0.63
Mesencephalon1.86 ± 0.65
Myelencephalon1.72 ± 0.65
Occipital Lobe1.72 ± 0.66
Parietal Lobe1.7 ± 0.74
Pontine Tegmentum1.64 ± 0.61
Striatum1.55 ± 0.53
Subthalamus1.83 ± 0.62
Temporal Lobe1.57 ± 0.6
Thalamus1.66 ± 0.56
White Matter2.12 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Enpp3CBCerebellum0.92
1.61
Enpp3CTXCerebral cortex0.24
0.36
Enpp3HIPHippocampal region0.04
0.09
Enpp3HPFHippocampal formation0.03
0.06
Enpp3HYHypothalamus0.02
0.02
Enpp3LSXLateral septal complex0.02
0
Enpp3MBMidbrain0.05
0.21
Enpp3MYMedulla0
0
Enpp3OLFOlfactory bulb0.15
0.27
Enpp3PPons0.06
0.12
Enpp3PALPallidum0
0
Enpp3RHPRetrohippocampal region0.01
0
Enpp3sAMYStriatum-like amygdalar nuclei0
0
Enpp3STRStriatum0.02
0.02
Enpp3STRdStriatum dorsal region0.02
0.02
Enpp3STRvStriatum ventral region0
0
Enpp3THThalamus0.01
0.02
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018