Annotation Detail for CPSF3
Basic Information Top
| Gene Symbol: | CPSF3 ( CPSF,CPSF-73,CPSF73,YSH1 ) |
|---|---|
| Gene Full Name: | cleavage and polyadenylation specific factor 3, 73kDa |
| Band: | 2p25.1 |
| Quick Links | Entrez ID:51692; OMIM: 606029; Uniprot ID:CPSF3_HUMAN; ENSEMBL ID: ENSG00000119203; HGNC ID: 2326 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.515972
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 43 / 564012 | 76 | |
| neonate | 13 / 31097 | 418 |  |
| infant | 6 / 23620 | 254 | |
| juvenile | 20 / 55556 | 359 | |
| adult | 162 / 1939121 | 83 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 61 / 263845 | 231 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 14 / 96359 | 145 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 298 / 3360307 | 88 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 40 / 125680 | 318 | |
| prostate cancer | 8 / 102680 | 77 | |
| retinoblastoma | 17 / 46356 | 366 | |
| skin tumor | 13 / 124949 | 104 | |
| soft tissue/muscle tissue tumor | 56 / 125191 | 447 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 3 / 13106 | 228 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 2 / 29757 | 67 | |
| blood | 15 / 123478 | 121 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 5 / 48801 | 102 | |
| brain | 96 / 1100989 | 87 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 53 / 149255 | 355 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 3 / 20209 | 148 | |
| eye | 22 / 211054 | 104 | |
| heart | 14 / 89626 | 156 | |
| intestine | 16 / 234472 | 68 | |
| kidney | 31 / 211777 | 146 | |
| larynx | 0 / 24145 | 0 | |
| liver | 14 / 207743 | 67 | |
| lung | 18 / 336974 | 53 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 10 / 153271 | 65 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 8 / 107715 | 74 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 5 / 41328 | 120 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 18 / 280825 | 64 | |
| prostate | 21 / 189345 | 110 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 22 / 210574 | 104 | |
| spleen | 13 / 53952 | 240 | |
| stomach | 2 / 96619 | 20 | |
| testis | 69 / 330442 | 208 | |
| thymus | 15 / 81131 | 184 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 24 / 232878 | 103 | |
| vascular | 10 / 51780 | 193 | |
Microarray in - Probe name: CUST_11316_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.54 ± 0.43 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.67 ± 0.37 | |
| Basal Part of Pons | 5.97 ± 0.23 | |
| Cerebellar Cortex | 5.66 ± 0.29 | |
| Cerebellar Nuclei | 5.85 ± 0.32 | |
| Claustrum | 5.5 ± 0.61 | |
| Epithalamus | 6 ± 0.25 | |
| Frontal Lobe | 5.81 ± 0.29 | |
| Globus Pallidus | 6.14 ± 0.19 | |
| Hypothalamus | 5.83 ± 0.18 | |
| Insula | 5.73 ± 0.34 | |
| Limbic Lobe | 5.55 ± 0.34 | |
| Mesencephalon | 5.62 ± 0.43 | |
| Myelencephalon | 5.67 ± 0.34 | |
| Occipital Lobe | 5.61 ± 0.35 | |
| Parietal Lobe | 5.71 ± 0.35 | |
| Pontine Tegmentum | 5.76 ± 0.27 | |
| Striatum | 5.79 ± 0.18 | |
| Subthalamus | 5.84 ± 0.21 | |
| Temporal Lobe | 5.67 ± 0.26 | |
| Thalamus | 5.86 ± 0.28 | |
| White Matter | 6.59 ± 0.25 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cpsf3 | CB | Cerebellum | 30.02 | |
| 66.57 | | |||
| Cpsf3 | CTX | Cerebral cortex | 91.74 | |
| 76.57 | | |||
| Cpsf3 | HIP | Hippocampal region | 56.47 | |
| 85.94 | | |||
| Cpsf3 | HPF | Hippocampal formation | 68.48 | |
| 85.87 | | |||
| Cpsf3 | HY | Hypothalamus | 65.36 | |
| 56.1 | | |||
| Cpsf3 | LSX | Lateral septal complex | 56.18 | |
| 41.46 | | |||
| Cpsf3 | MB | Midbrain | 53.73 | |
| 49.22 | | |||
| Cpsf3 | MY | Medulla | 72.13 | |
| 83.22 | | |||
| Cpsf3 | OLF | Olfactory bulb | 90.28 | |
| 84.99 | | |||
| Cpsf3 | P | Pons | 57.11 | |
| 65.22 | | |||
| Cpsf3 | PAL | Pallidum | 67.63 | |
| 65.65 | | |||
| Cpsf3 | RHP | Retrohippocampal region | 96.08 | |
| 91.17 | | |||
| Cpsf3 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 91.16 | | |||
| Cpsf3 | STR | Striatum | 100 | |
| 95.27 | | |||
| Cpsf3 | STRd | Striatum dorsal region | 100 | |
| 97.93 | | |||
| Cpsf3 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Cpsf3 | TH | Thalamus | 87.78 | |
| 85.69 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CPSF3_HUMAN_16 | 10 | 16 | 25 | PLGAGQEVGR | PRIDE |
| CPSF3_HUMAN_2 | 14 | 2 | 15 | SAIPAEESDQLLIR | PRIDE |
| CPSF3_HUMAN_2 | 24 | 2 | 25 | SAIPAEESDQLLIRPLGAGQEVGR | PRIDE |
| PAp00002348 | 11 | 222 | 232 | FCNTVHDIVNR | Peptide Atlas |