AutismKB 2.0

Annotation Detail for ACSL5


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Basic Information Top
Gene Symbol:ACSL5 ( ACS2,ACS5,FACL5 )
Gene Full Name: acyl-CoA synthetase long-chain family member 5
Band: 10q25.2
Quick LinksEntrez ID:51703; OMIM: 605677; Uniprot ID:ACSL5_HUMAN; ENSEMBL ID: ENSG00000197142; HGNC ID: 16526
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate1 / 3109732
infant0 / 236200 
juvenile14 / 55556251
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor27 / 114246236
esophageal tumor0 / 172900 
gastrointestinal tumor22 / 119369184
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia6 / 9584262
liver tumor17 / 96359176
lung tumor0 / 1031270 
lymphoma7 / 7175597
non-neoplasia19 / 97250195
normal192 / 336030757
ovarian tumor3 / 7668239
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites6 / 40015149
bladder4 / 29757134
blood14 / 123478113
bone2 / 7165527
bone marrow3 / 4880161
brain34 / 110098930
cervix2 / 4817141
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine69 / 234472294
kidney9 / 21177742
larynx0 / 241450 
liver24 / 207743115
lung25 / 33697474
lymph2 / 4427045
lymph node9 / 9161098
mammary gland1 / 1532716
mouth3 / 6705244
muscle7 / 10771564
nerve1 / 1576863
ovary4 / 10205139
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta12 / 28082542
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen9 / 53952166
stomach25 / 96619258
testis17 / 33044251
thymus12 / 81131147
thyroid0 / 474730 
tonsil2 / 16999117
trachea13 / 52413248
umbilical cord0 / 136800 
uterus31 / 232878133
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218322_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts93.7
Adipocyte174.15
AdrenalCortex27.9
Adrenalgland19.9
Amygdala27.05
Appendix34.95
AtrioventricularNode23.4
BDCA4+_DentriticCells54.25
Bonemarrow38.05
BronchialEpithelialCells16.6
CD105+_Endothelial45.6
CD14+_Monocytes67.25
CD19+_BCells(neg._sel.)71.85
CD33+_Myeloid68.75
CD34+174.05
CD4+_Tcells108.6
CD56+_NKCells230.7
CD71+_EarlyErythroid26.1
CD8+_Tcells113.05
CardiacMyocytes45.05
Caudatenucleus24.4
Cerebellum23.8
CerebellumPeduncles30.7
CiliaryGanglion25
CingulateCortex26.65
Colorectaladenocarcinoma28.35
DorsalRootGanglion21.9
FetalThyroid20.1
Fetalbrain23.7
Fetalliver26.65
Fetallung24.1
GlobusPallidus13
Heart53.7
Hypothalamus27.9
Kidney25.1
Leukemia_chronicMyelogenousK-56214
Leukemia_promyelocytic-HL-6032.9
Leukemialymphoblastic(MOLT-4)13.95
Liver55.6
Lung53.5
Lymphnode34.95
Lymphoma_burkitts(Daudi)48.9
Lymphoma_burkitts(Raji)65.35
MedullaOblongata22.75
OccipitalLobe19.9
OlfactoryBulb17.15
Ovary24.05
Pancreas80.15
PancreaticIslet37.2
ParietalLobe32.25
Pituitary32.5
Placenta19.7
Pons34.45
PrefrontalCortex38.5
Prostate29.1
Salivarygland22.65
SkeletalMuscle42.9
Skin23.65
SmoothMuscle13.3
Spinalcord26.85
SubthalamicNucleus24.45
SuperiorCervicalGanglion49.4
TemporalLobe22.15
Testis20.75
TestisGermCell21.2
TestisIntersitial22
TestisLeydigCell41.2
TestisSeminiferousTubule22.55
Thalamus27.45
Thymus25.05
Thyroid26.45
Tongue31.1
Tonsil32.7
Trachea44
TrigeminalGanglion29.85
Uterus42.9
UterusCorpus25.3
WholeBlood46
Wholebrain21.35
colon252.75
pineal_day22.94
pineal_night27.98
retina36.825
small_intestine692.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9901_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.35 ± 0.69
Basal Forebrain2.93 ± 0.65
Basal Part of Pons3.12 ± 0.79
Cerebellar Cortex2.88 ± 0.58
Cerebellar Nuclei3.88 ± 0.5
Claustrum3.44 ± 0.79
Epithalamus3.42 ± 0.71
Frontal Lobe3.29 ± 0.67
Globus Pallidus4.56 ± 0.36
Hypothalamus2.95 ± 0.73
Insula3.13 ± 0.39
Limbic Lobe3.17 ± 0.82
Mesencephalon3.48 ± 0.8
Myelencephalon3.38 ± 0.69
Occipital Lobe3.55 ± 0.64
Parietal Lobe3.33 ± 0.83
Pontine Tegmentum3.49 ± 0.69
Striatum3.82 ± 0.73
Subthalamus3.65 ± 0.1
Temporal Lobe3.25 ± 0.66
Thalamus3.57 ± 0.55
White Matter3.88 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acsl5CBCerebellum100
100
Acsl5CTXCerebral cortex100
100
Acsl5HIPHippocampal region100
100
Acsl5HPFHippocampal formation100
100
Acsl5HYHypothalamus100
100
Acsl5LSXLateral septal complex100
100
Acsl5MBMidbrain100
100
Acsl5MYMedulla100
100
Acsl5OLFOlfactory bulb100
100
Acsl5PPons100
100
Acsl5PALPallidum100
100
Acsl5RHPRetrohippocampal region100
100
Acsl5sAMYStriatum-like amygdalar nuclei100
100
Acsl5STRStriatum100
100
Acsl5STRdStriatum dorsal region100
100
Acsl5STRvStriatum ventral region100
100
Acsl5THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001439 26 288 313 CVEHAYEPTPDDVAISYLPLAHMFER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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