AutismKB 2.0

Annotation Detail for GPRC5B


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Basic Information Top
Gene Symbol:GPRC5B ( RAIG-2,RAIG2 )
Gene Full Name: G protein-coupled receptor, family C, group 5, member B
Band: 16p12.3
Quick LinksEntrez ID:51704; OMIM: 605948; Uniprot ID:GPC5B_HUMAN; ENSEMBL ID: ENSG00000167191; HGNC ID: 13308
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst6 / 6231996
fetus37 / 56401265
neonate0 / 310970 
infant3 / 23620127
juvenile0 / 555560 
adult124 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor1 / 1193698
germ cell tumor24 / 26384590
glioma10 / 10688393
head and neck tumor6 / 13630244
kidney tumor21 / 68959304
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia13 / 97250133
normal504 / 3360307149
ovarian tumor9 / 76682117
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain465 / 1100989422
cervix0 / 481710 
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue13 / 21572260
esophagus2 / 2020998
eye16 / 21105475
heart4 / 8962644
intestine5 / 23447221
kidney29 / 211777136
larynx1 / 2414541
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth5 / 6705274
muscle2 / 10771518
nerve0 / 157680 
ovary16 / 102051156
pancreas2 / 2148129
parathyroid8 / 20539389
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta10 / 28082535
prostate3 / 18934515
salivary gland0 / 201550 
skin12 / 21057456
spleen2 / 5395237
stomach4 / 9661941
testis47 / 330442142
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203632_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte7.2
AdrenalCortex6.6
Adrenalgland8.4
Amygdala1729.2
Appendix7.05
AtrioventricularNode7
BDCA4+_DentriticCells4.35
Bonemarrow6.3
BronchialEpithelialCells5.25
CD105+_Endothelial4.35
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.35
CD34+5.25
CD4+_Tcells4.55
CD56+_NKCells4.9
CD71+_EarlyErythroid5.25
CD8+_Tcells3.85
CardiacMyocytes20.35
Caudatenucleus1408.65
Cerebellum837.45
CerebellumPeduncles385.8
CiliaryGanglion4.8
CingulateCortex719.2
Colorectaladenocarcinoma6.2
DorsalRootGanglion7.9
FetalThyroid12.35
Fetalbrain32.2
Fetalliver5.45
Fetallung6.7
GlobusPallidus366.25
Heart61.65
Hypothalamus2492.15
Kidney45
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)4.25
Liver8.35
Lung7.25
Lymphnode21.6
Lymphoma_burkitts(Daudi)6.2
Lymphoma_burkitts(Raji)8
MedullaOblongata1152.05
OccipitalLobe1575.4
OlfactoryBulb528.45
Ovary5.35
Pancreas7.2
PancreaticIslet16.65
ParietalLobe1607.55
Pituitary36.15
Placenta28
Pons438.8
PrefrontalCortex1866
Prostate17.6
Salivarygland12.2
SkeletalMuscle7.7
Skin4.3
SmoothMuscle245.05
Spinalcord1918.5
SubthalamicNucleus442.65
SuperiorCervicalGanglion9.45
TemporalLobe170.05
Testis225.75
TestisGermCell255.7
TestisIntersitial45.3
TestisLeydigCell43.25
TestisSeminiferousTubule107.8
Thalamus1699.45
Thymus8.4
Thyroid34.85
Tongue6.25
Tonsil5.7
Trachea24.45
TrigeminalGanglion7.05
Uterus8.55
UterusCorpus4.95
WholeBlood6.15
Wholebrain1768.6
colon7.4
pineal_day325.96
pineal_night283.18
retina1359.5
small_intestine14.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P324327
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.48 ± 0.47
Basal Forebrain10.42 ± 0.33
Basal Part of Pons10.04 ± 0.56
Cerebellar Cortex9.74 ± 0.23
Cerebellar Nuclei10.67 ± 0.49
Claustrum9.34 ± 0.56
Epithalamus10.27 ± 0.51
Frontal Lobe10.11 ± 0.68
Globus Pallidus11.59 ± 0.29
Hypothalamus10.19 ± 0.33
Insula9.74 ± 0.38
Limbic Lobe9.62 ± 0.63
Mesencephalon10.26 ± 0.67
Myelencephalon10.19 ± 0.6
Occipital Lobe10.06 ± 0.65
Parietal Lobe10 ± 0.6
Pontine Tegmentum10.22 ± 0.44
Striatum10.69 ± 0.58
Subthalamus10.3 ± 0.23
Temporal Lobe9.89 ± 0.48
Thalamus10.67 ± 0.4
White Matter12.65 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gprc5bCBCerebellum89.38
100
Gprc5bCTXCerebral cortex100
100
Gprc5bHIPHippocampal region100
100
Gprc5bHPFHippocampal formation100
100
Gprc5bHYHypothalamus100
100
Gprc5bLSXLateral septal complex100
100
Gprc5bMBMidbrain100
100
Gprc5bMYMedulla100
100
Gprc5bOLFOlfactory bulb100
100
Gprc5bPPons100
100
Gprc5bPALPallidum100
100
Gprc5bRHPRetrohippocampal region100
100
Gprc5bsAMYStriatum-like amygdalar nuclei100
93.5
Gprc5bSTRStriatum95.44
79.94
Gprc5bSTRdStriatum dorsal region88.78
74.98
Gprc5bSTRvStriatum ventral region90.31
71.39
Gprc5bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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