AutismKB 2.0

Annotation Detail for FBXO40


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Basic Information Top
Gene Symbol:FBXO40 ( FBX40,KIAA1195,MGC129902,MGC129903 )
Gene Full Name: F-box protein 40
Band: 3q13.33
Quick LinksEntrez ID:51725; OMIM: 609107; Uniprot ID:FBX40_HUMAN; ENSEMBL ID: ENSG00000163833; HGNC ID: 29816
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver4 / 20774319
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220164_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte6.6
AdrenalCortex8.05
Adrenalgland5.95
Amygdala6.65
Appendix8.1
AtrioventricularNode5.75
BDCA4+_DentriticCells6.9
Bonemarrow7.2
BronchialEpithelialCells6.3
CD105+_Endothelial6.5
CD14+_Monocytes6.95
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid8.05
CD34+7.85
CD4+_Tcells6.8
CD56+_NKCells7.45
CD71+_EarlyErythroid6.35
CD8+_Tcells5.95
CardiacMyocytes12.7
Caudatenucleus6
Cerebellum5.5
CerebellumPeduncles7.95
CiliaryGanglion5.25
CingulateCortex7
Colorectaladenocarcinoma6.6
DorsalRootGanglion5.6
FetalThyroid6.55
Fetalbrain6.35
Fetalliver5.95
Fetallung5
GlobusPallidus5.25
Heart48.1
Hypothalamus7.05
Kidney6
Leukemia_chronicMyelogenousK-5625.95
Leukemia_promyelocytic-HL-605.85
Leukemialymphoblastic(MOLT-4)5.1
Liver9.9
Lung7.25
Lymphnode5.45
Lymphoma_burkitts(Daudi)8.7
Lymphoma_burkitts(Raji)10.25
MedullaOblongata5.85
OccipitalLobe5.85
OlfactoryBulb5.05
Ovary4.8
Pancreas5.5
PancreaticIslet7.05
ParietalLobe7.45
Pituitary7.7
Placenta6.55
Pons6.6
PrefrontalCortex8.15
Prostate7.5
Salivarygland5.55
SkeletalMuscle21.35
Skin5.95
SmoothMuscle7.45
Spinalcord7.05
SubthalamicNucleus6.15
SuperiorCervicalGanglion9.35
TemporalLobe6.2
Testis5.65
TestisGermCell5.25
TestisIntersitial5.6
TestisLeydigCell6.85
TestisSeminiferousTubule5.7
Thalamus6.8
Thymus5.15
Thyroid8.4
Tongue7.55
Tonsil6.75
Trachea5.45
TrigeminalGanglion7.9
Uterus5.2
UterusCorpus7.35
WholeBlood7.25
Wholebrain5.55
colon6.7
pineal_day7.94
pineal_night7.92
retina8.1
small_intestine6.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P280684
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.11 ± 1.17
Basal Forebrain2.85 ± 0.36
Basal Part of Pons2.92 ± 0.93
Cerebellar Cortex2.33 ± 0.46
Cerebellar Nuclei3.08 ± 0.61
Claustrum3.49 ± 0.59
Epithalamus2.25 ± 0.82
Frontal Lobe3.14 ± 0.73
Globus Pallidus2.32 ± 0.71
Hypothalamus2.72 ± 0.76
Insula3.31 ± 0.42
Limbic Lobe2.6 ± 0.84
Mesencephalon2.82 ± 0.67
Myelencephalon2.79 ± 0.72
Occipital Lobe2.16 ± 0.78
Parietal Lobe3.05 ± 0.76
Pontine Tegmentum2.78 ± 0.88
Striatum1.77 ± 0.87
Subthalamus2.76 ± 0.71
Temporal Lobe2.97 ± 0.75
Thalamus2.68 ± 0.87
White Matter1.95 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo40CBCerebellum2.82
4.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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