AutismKB 2.0

Annotation Detail for SEPX1


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Basic Information Top
Gene Symbol:SEPX1 ( MGC3344,MSRB1,SELR,SELX )
Gene Full Name: selenoprotein X, 1
Band: 16p13.3
Quick LinksEntrez ID:51734; OMIM: 606216; Uniprot ID:MSRB1_HUMAN; ENSEMBL ID: ENSG00000198736; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus24 / 56401242
neonate2 / 3109764
infant1 / 2362042
juvenile0 / 555560 
adult105 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma8 / 10688374
head and neck tumor1 / 1363027
kidney tumor8 / 68959116
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor12 / 103127116
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal147 / 336030743
ovarian tumor5 / 7668265
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow2 / 4880140
brain19 / 110098917
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye13 / 21105461
heart3 / 8962633
intestine23 / 23447298
kidney23 / 211777108
larynx0 / 241450 
liver17 / 20774381
lung26 / 33697477
lymph1 / 4427022
lymph node2 / 9161021
mammary gland7 / 15327145
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary5 / 10205148
pancreas18 / 21481283
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate10 / 18934552
salivary gland1 / 2015549
skin18 / 21057485
spleen3 / 5395255
stomach6 / 9661962
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord2 / 13680146
uterus20 / 23287885
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P129492
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.85 ± 0.57
Basal Forebrain4.05 ± 0.36
Basal Part of Pons3.99 ± 0.54
Cerebellar Cortex4.18 ± 0.62
Cerebellar Nuclei3.98 ± 0.38
Claustrum3.49 ± 0.85
Epithalamus4.31 ± 0.57
Frontal Lobe4.21 ± 0.54
Globus Pallidus4.25 ± 0.29
Hypothalamus4.15 ± 0.4
Insula4.16 ± 0.5
Limbic Lobe4.02 ± 0.52
Mesencephalon4.23 ± 0.63
Myelencephalon4.11 ± 0.52
Occipital Lobe3.89 ± 0.5
Parietal Lobe4.07 ± 0.57
Pontine Tegmentum4.09 ± 0.55
Striatum4.29 ± 0.49
Subthalamus3.87 ± 1.1
Temporal Lobe4.11 ± 0.5
Thalamus4.11 ± 0.52
White Matter4.21 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sepx1CBCerebellum20.47
24.84
Sepx1CTXCerebral cortex63.44
49.87
Sepx1HIPHippocampal region34.35
46.17
Sepx1HPFHippocampal formation38.68
42.97
Sepx1HYHypothalamus6.41
5.38
Sepx1LSXLateral septal complex7.14
4.97
Sepx1MBMidbrain15.44
14.92
Sepx1MYMedulla17.92
23.32
Sepx1OLFOlfactory bulb39.19
35.83
Sepx1PPons15.8
20.51
Sepx1PALPallidum17.42
18
Sepx1RHPRetrohippocampal region45.25
38.7
Sepx1sAMYStriatum-like amygdalar nuclei38.89
28.96
Sepx1STRStriatum28.91
21.81
Sepx1STRdStriatum dorsal region30.53
23.16
Sepx1STRvStriatum ventral region24.78
18.93
Sepx1THThalamus34.25
33.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018