AutismKB 2.0

Annotation Detail for RAB8B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RAB8B ( FLJ38125 )
Gene Full Name: RAB8B, member RAS oncogene family
Band: 15q22.2
Quick LinksEntrez ID:51762; OMIM: 613532; Uniprot ID:RAB8B_HUMAN; ENSEMBL ID: ENSG00000166128; HGNC ID: 30273
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus32 / 56401256
neonate2 / 3109764
infant1 / 2362042
juvenile1 / 5555617
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor13 / 26384549
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal173 / 336030751
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood12 / 12347897
bone5 / 7165569
bone marrow7 / 48801143
brain72 / 110098965
cervix0 / 481710 
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney3 / 21177714
larynx1 / 2414541
liver5 / 20774324
lung9 / 33697426
lymph0 / 442700 
lymph node11 / 91610120
mammary gland6 / 15327139
mouth0 / 670520 
muscle18 / 107715167
nerve1 / 1576863
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta17 / 28082560
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen3 / 5395255
stomach1 / 9661910
testis20 / 33044260
thymus7 / 8113186
thyroid0 / 474730 
tonsil1 / 1699958
trachea7 / 52413133
umbilical cord0 / 136800 
uterus11 / 23287847
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219210_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts41.5
Adipocyte10.55
AdrenalCortex10.7
Adrenalgland7.85
Amygdala9.15
Appendix11.9
AtrioventricularNode9.3
BDCA4+_DentriticCells10.45
Bonemarrow9.55
BronchialEpithelialCells9.4
CD105+_Endothelial9.35
CD14+_Monocytes15.25
CD19+_BCells(neg._sel.)9.75
CD33+_Myeloid26.5
CD34+11.15
CD4+_Tcells10.75
CD56+_NKCells30.85
CD71+_EarlyErythroid9
CD8+_Tcells12.85
CardiacMyocytes13.5
Caudatenucleus8.4
Cerebellum7.7
CerebellumPeduncles10.9
CiliaryGanglion8.1
CingulateCortex9.75
Colorectaladenocarcinoma9.15
DorsalRootGanglion7.9
FetalThyroid8.85
Fetalbrain9.05
Fetalliver8.3
Fetallung7.55
GlobusPallidus7.15
Heart12.9
Hypothalamus9.6
Kidney7.8
Leukemia_chronicMyelogenousK-5627.65
Leukemia_promyelocytic-HL-607.2
Leukemialymphoblastic(MOLT-4)7.25
Liver12.6
Lung10.25
Lymphnode8.45
Lymphoma_burkitts(Daudi)11.4
Lymphoma_burkitts(Raji)12.8
MedullaOblongata8.45
OccipitalLobe8.35
OlfactoryBulb7.35
Ovary7.8
Pancreas7.3
PancreaticIslet9.95
ParietalLobe10.25
Pituitary10.8
Placenta7.65
Pons9.5
PrefrontalCortex11.2
Prostate10.45
Salivarygland7.55
SkeletalMuscle14.65
Skin7.6
SmoothMuscle10.75
Spinalcord9.9
SubthalamicNucleus9.3
SuperiorCervicalGanglion17.7
TemporalLobe8.5
Testis15.05
TestisGermCell13.45
TestisIntersitial22.35
TestisLeydigCell19.2
TestisSeminiferousTubule11.7
Thalamus9.4
Thymus7.2
Thyroid10.25
Tongue9.55
Tonsil9.2
Trachea7.6
TrigeminalGanglion11.95
Uterus7.6
UterusCorpus8.75
WholeBlood19.95
Wholebrain7.45
colon9.5
pineal_day11.42
pineal_night11.38
retina11.275
small_intestine9.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P317465
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.42 ± 0.34
Basal Forebrain6.53 ± 0.31
Basal Part of Pons6.09 ± 0.14
Cerebellar Cortex6.23 ± 0.28
Cerebellar Nuclei6.45 ± 0.28
Claustrum6.66 ± 0.36
Epithalamus5.99 ± 0.51
Frontal Lobe6.4 ± 0.29
Globus Pallidus7.02 ± 0.26
Hypothalamus6.21 ± 0.34
Insula6.45 ± 0.26
Limbic Lobe6.49 ± 0.36
Mesencephalon6.46 ± 0.36
Myelencephalon6.44 ± 0.36
Occipital Lobe6.14 ± 0.36
Parietal Lobe6.3 ± 0.27
Pontine Tegmentum6.41 ± 0.35
Striatum6.15 ± 0.3
Subthalamus6.36 ± 0.09
Temporal Lobe6.47 ± 0.29
Thalamus6.55 ± 0.27
White Matter7.27 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rab8bCBCerebellum0
0
Rab8bCTXCerebral cortex0
0
Rab8bHIPHippocampal region0
0
Rab8bHPFHippocampal formation0
0
Rab8bHYHypothalamus0
0
Rab8bLSXLateral septal complex0
0
Rab8bMBMidbrain0
0
Rab8bMYMedulla0
0
Rab8bOLFOlfactory bulb0
0
Rab8bPPons0
0
Rab8bPALPallidum0
0
Rab8bRHPRetrohippocampal region0
0
Rab8bsAMYStriatum-like amygdalar nuclei0
0
Rab8bSTRStriatum0
0
Rab8bSTRdStriatum dorsal region0
0
Rab8bSTRvStriatum ventral region0
0
Rab8bTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005812 12 105 116 NIEEHASSDVER Peptide Atlas
RAB8B_HUMAN_0 0 0 0 LLLIGDSGVGK PRIDE
RAB8B_HUMAN_0 0 0 0 SSANVEEAFFTLAR PRIDE
RAB8B_HUMAN_10 11 10 20 LLLIGDSGVGK PRIDE
RAB8B_HUMAN_104 12 104 115 NIEEHASSDVER PRIDE
RAB8B_HUMAN_153 14 153 166 SSANVEEAFFTLAR PRIDE
RAB8B_HUMAN_3 7 3 9 TYDYLFK PRIDE
RAB8B_HUMAN_56 13 56 68 IKLQIWDTAGQER PRIDE
RAB8B_HUMAN_58 11 58 68 LQIWDTAGQER PRIDE
RAB8B_HUMAN_71 8 71 78 TITTAYYR PRIDE
RAB8B_HUMAN_79 15 79 93 GAMGIMLVYDITNEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved