AutismKB 2.0

Annotation Detail for INPP5K


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Basic Information Top
Gene Symbol:INPP5K ( PPS,SKIP )
Gene Full Name: inositol polyphosphate-5-phosphatase K
Band: 17p13.3
Quick LinksEntrez ID:51763; OMIM: 607875; Uniprot ID:INP5K_HUMAN; ENSEMBL ID: ENSG00000132376; HGNC ID: 33882
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus48 / 56401285
neonate1 / 3109732
infant2 / 2362084
juvenile2 / 5555635
adult130 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma9 / 82823108
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor10 / 13630273
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma6 / 7175583
non-neoplasia8 / 9725082
normal257 / 336030776
ovarian tumor2 / 7668226
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor11 / 12494988
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood10 / 12347880
bone4 / 7165555
bone marrow0 / 488010 
brain91 / 110098982
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye38 / 211054180
heart4 / 8962644
intestine12 / 23447251
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung16 / 33697447
lymph4 / 4427090
lymph node19 / 91610207
mammary gland7 / 15327145
mouth5 / 6705274
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas20 / 21481293
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta25 / 28082589
prostate10 / 18934552
salivary gland0 / 201550 
skin15 / 21057471
spleen8 / 53952148
stomach1 / 9661910
testis18 / 33044254
thymus3 / 8113136
thyroid5 / 47473105
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202781_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.15
Adipocyte8.45
AdrenalCortex8.2
Adrenalgland8.5
Amygdala8.2
Appendix7.9
AtrioventricularNode6.1
BDCA4+_DentriticCells29.15
Bonemarrow9.65
BronchialEpithelialCells6.7
CD105+_Endothelial7.75
CD14+_Monocytes27.9
CD19+_BCells(neg._sel.)12.15
CD33+_Myeloid13.75
CD34+10.15
CD4+_Tcells19.2
CD56+_NKCells49.75
CD71+_EarlyErythroid29.3
CD8+_Tcells15.85
CardiacMyocytes10.4
Caudatenucleus8.9
Cerebellum9
CerebellumPeduncles9.25
CiliaryGanglion5.55
CingulateCortex8.6
Colorectaladenocarcinoma13.65
DorsalRootGanglion5.95
FetalThyroid9.6
Fetalbrain8.55
Fetalliver6.75
Fetallung8.15
GlobusPallidus10
Heart27.05
Hypothalamus8.95
Kidney10.35
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-607.6
Leukemialymphoblastic(MOLT-4)6.1
Liver10.45
Lung11.4
Lymphnode7.05
Lymphoma_burkitts(Daudi)11.3
Lymphoma_burkitts(Raji)10.85
MedullaOblongata11.5
OccipitalLobe8.05
OlfactoryBulb6.05
Ovary5.4
Pancreas6.1
PancreaticIslet8.65
ParietalLobe10.2
Pituitary9.9
Placenta10.35
Pons9.95
PrefrontalCortex8.7
Prostate10.85
Salivarygland6.25
SkeletalMuscle12.45
Skin6.1
SmoothMuscle8.55
Spinalcord9.7
SubthalamicNucleus7.15
SuperiorCervicalGanglion9.05
TemporalLobe9.45
Testis23.25
TestisGermCell9.7
TestisIntersitial9.5
TestisLeydigCell10.85
TestisSeminiferousTubule14.85
Thalamus9.8
Thymus6.35
Thyroid13.35
Tongue7.65
Tonsil8.2
Trachea8.15
TrigeminalGanglion7.75
Uterus6.25
UterusCorpus7
WholeBlood8.85
Wholebrain10.45
colon7.9
pineal_day8.96
pineal_night9.02
retina129.125
small_intestine7.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P55076
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.42 ± 0.26
Basal Forebrain9.53 ± 0.16
Basal Part of Pons9.86 ± 0.18
Cerebellar Cortex9.66 ± 0.24
Cerebellar Nuclei9.59 ± 0.29
Claustrum9.55 ± 0.21
Epithalamus9.13 ± 0.28
Frontal Lobe9.76 ± 0.28
Globus Pallidus9.28 ± 0.22
Hypothalamus9.58 ± 0.35
Insula9.81 ± 0.22
Limbic Lobe9.8 ± 0.21
Mesencephalon9.59 ± 0.22
Myelencephalon9.67 ± 0.29
Occipital Lobe9.45 ± 0.21
Parietal Lobe9.62 ± 0.23
Pontine Tegmentum9.55 ± 0.27
Striatum9.57 ± 0.25
Subthalamus9.71 ± 0.06
Temporal Lobe9.68 ± 0.23
Thalamus9.63 ± 0.23
White Matter9.62 ± 0.25
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00501260 10 197 206 IEDFGLHFVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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