AutismKB 2.0

Annotation Detail for PER1


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Basic Information Top
Gene Symbol:PER1 ( MGC88021,PER,RIGUI,hPER )
Gene Full Name: period homolog 1 (Drosophila)
Band: 17p13.1
Quick LinksEntrez ID:5187; OMIM: 602260; Uniprot ID:PER1_HUMAN; ENSEMBL ID: ENSG00000179094; HGNC ID: 8845
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult144 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor13 / 26384549
glioma7 / 10688365
head and neck tumor9 / 13630266
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal261 / 336030777
ovarian tumor7 / 7668291
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites2 / 4001549
bladder3 / 29757100
blood7 / 12347856
bone10 / 71655139
bone marrow0 / 488010 
brain131 / 1100989118
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye19 / 21105490
heart1 / 8962611
intestine7 / 23447229
kidney7 / 21177733
larynx3 / 24145124
liver4 / 20774319
lung20 / 33697459
lymph0 / 442700 
lymph node3 / 9161032
mammary gland9 / 15327158
mouth3 / 6705244
muscle9 / 10771583
nerve7 / 15768443
ovary10 / 10205197
pancreas24 / 214812111
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate5 / 18934526
salivary gland1 / 2015549
skin1 / 2105744
spleen7 / 53952129
stomach5 / 9661951
testis45 / 330442136
thymus16 / 81131197
thyroid6 / 47473126
tonsil0 / 169990 
trachea21 / 52413400
umbilical cord0 / 136800 
uterus26 / 232878111
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202861_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.5
Adipocyte25.8
AdrenalCortex251.8
Adrenalgland53.15
Amygdala14.4
Appendix18.1
AtrioventricularNode27.55
BDCA4+_DentriticCells20.6
Bonemarrow16.35
BronchialEpithelialCells20.75
CD105+_Endothelial17.75
CD14+_Monocytes25.2
CD19+_BCells(neg._sel.)17.55
CD33+_Myeloid90.7
CD34+26.9
CD4+_Tcells39.2
CD56+_NKCells21.35
CD71+_EarlyErythroid55.2
CD8+_Tcells31.75
CardiacMyocytes17.4
Caudatenucleus16.6
Cerebellum15.15
CerebellumPeduncles18.6
CiliaryGanglion14.25
CingulateCortex28.45
Colorectaladenocarcinoma17.15
DorsalRootGanglion18.7
FetalThyroid19.9
Fetalbrain14.05
Fetalliver15.1
Fetallung102.3
GlobusPallidus14.15
Heart55.45
Hypothalamus40.05
Kidney21.5
Leukemia_chronicMyelogenousK-56214.45
Leukemia_promyelocytic-HL-6014.15
Leukemialymphoblastic(MOLT-4)12.5
Liver38.35
Lung128.55
Lymphnode23.55
Lymphoma_burkitts(Daudi)20.25
Lymphoma_burkitts(Raji)26.25
MedullaOblongata17.85
OccipitalLobe18.15
OlfactoryBulb111.1
Ovary54.15
Pancreas11.2
PancreaticIslet22.9
ParietalLobe30.05
Pituitary25.1
Placenta16.65
Pons26.15
PrefrontalCortex42.6
Prostate21
Salivarygland15.05
SkeletalMuscle52.05
Skin35.25
SmoothMuscle10.1
Spinalcord47.4
SubthalamicNucleus14.45
SuperiorCervicalGanglion20.35
TemporalLobe16.55
Testis17.1
TestisGermCell13.2
TestisIntersitial14.6
TestisLeydigCell25.2
TestisSeminiferousTubule27.5
Thalamus19.75
Thymus14.45
Thyroid77.95
Tongue51.8
Tonsil15.6
Trachea42.95
TrigeminalGanglion15.65
Uterus26.9
UterusCorpus20.25
WholeBlood13.6
Wholebrain23.55
colon34.05
pineal_day117.28
pineal_night78.68
retina283.3
small_intestine25.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12126_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.39 ± 0.77
Basal Forebrain2.99 ± 0.43
Basal Part of Pons3.08 ± 0.39
Cerebellar Cortex3.67 ± 0.64
Cerebellar Nuclei3.22 ± 0.61
Claustrum3.43 ± 0.6
Epithalamus3.9 ± 0.9
Frontal Lobe3.46 ± 0.6
Globus Pallidus2.29 ± 0.78
Hypothalamus3.3 ± 0.86
Insula3.48 ± 0.48
Limbic Lobe3.23 ± 0.67
Mesencephalon3.37 ± 0.65
Myelencephalon3.38 ± 0.62
Occipital Lobe3.45 ± 0.62
Parietal Lobe3.24 ± 0.71
Pontine Tegmentum3.29 ± 0.65
Striatum3.18 ± 0.58
Subthalamus3.39 ± 0.85
Temporal Lobe3.47 ± 0.62
Thalamus3.2 ± 0.56
White Matter2.5 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Per1CBCerebellum82.46
72.78
Per1CTXCerebral cortex100
87.08
Per1HIPHippocampal region73.29
64.77
Per1HPFHippocampal formation83
71.73
Per1HYHypothalamus48.93
33.58
Per1LSXLateral septal complex70.94
62.04
Per1MBMidbrain45.36
33.3
Per1MYMedulla41.66
32.18
Per1OLFOlfactory bulb100
87.79
Per1PPons39.9
31.56
Per1PALPallidum40.7
32.21
Per1RHPRetrohippocampal region84.1
72.61
Per1sAMYStriatum-like amygdalar nuclei62.37
45.67
Per1STRStriatum87.2
74.58
Per1STRdStriatum dorsal region90.01
77.25
Per1STRvStriatum ventral region100
81.1
Per1THThalamus80.87
69.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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