AutismKB 2.0

Annotation Detail for CFP


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Basic Information Top
Gene Symbol:CFP ( BFD,PFC,PFD,PROPERDIN )
Gene Full Name: complement factor properdin
Band: Xp11.23
Quick LinksEntrez ID:5199; OMIM: 300383; Uniprot ID:PROP_HUMAN; ENSEMBL ID: ENSG00000126759; HGNC ID: 8864
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus0 / 5640120 
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor5 / 7668265
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone1 / 7165513
bone marrow1 / 4880120
brain2 / 11009891
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary6 / 10205158
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen10 / 53952185
stomach0 / 966190 
testis0 / 3304420 
thymus5 / 8113161
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206380_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.55
Adipocyte5.25
AdrenalCortex5
Adrenalgland3.9
Amygdala4.7
Appendix4.65
AtrioventricularNode3.65
BDCA4+_DentriticCells223.3
Bonemarrow29.1
BronchialEpithelialCells4.5
CD105+_Endothelial16.05
CD14+_Monocytes952.8
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid727.6
CD34+11.25
CD4+_Tcells5.35
CD56+_NKCells13.45
CD71+_EarlyErythroid4.35
CD8+_Tcells4.35
CardiacMyocytes5.75
Caudatenucleus4.15
Cerebellum3.75
CerebellumPeduncles5.25
CiliaryGanglion3.3
CingulateCortex7.75
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.6
FetalThyroid4.45
Fetalbrain4.55
Fetalliver4.05
Fetallung4.25
GlobusPallidus3.95
Heart10.1
Hypothalamus4.9
Kidney3.8
Leukemia_chronicMyelogenousK-5624.15
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.6
Liver13.95
Lung5.55
Lymphnode10
Lymphoma_burkitts(Daudi)5.9
Lymphoma_burkitts(Raji)6.35
MedullaOblongata4.15
OccipitalLobe4.1
OlfactoryBulb3.65
Ovary3.1
Pancreas3.7
PancreaticIslet4.9
ParietalLobe4.9
Pituitary5.5
Placenta4.75
Pons4.4
PrefrontalCortex5.6
Prostate5.25
Salivarygland3.7
SkeletalMuscle5.3
Skin3.55
SmoothMuscle5.15
Spinalcord4.9
SubthalamicNucleus4.55
SuperiorCervicalGanglion5.45
TemporalLobe4.2
Testis3.9
TestisGermCell3.8
TestisIntersitial3.8
TestisLeydigCell4.55
TestisSeminiferousTubule3.95
Thalamus4.65
Thymus3.7
Thyroid5.65
Tongue4.5
Tonsil4.45
Trachea3.9
TrigeminalGanglion4.7
Uterus3.7
UterusCorpus4.1
WholeBlood767.8
Wholebrain3.8
colon4.6
pineal_day5.66
pineal_night5.52
retina5.475
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13301_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.2 ± 0.39
Basal Forebrain4.12 ± 0.33
Basal Part of Pons3.92 ± 0.32
Cerebellar Cortex4.29 ± 0.41
Cerebellar Nuclei3.68 ± 0.51
Claustrum4.05 ± 0.58
Epithalamus3.71 ± 0.3
Frontal Lobe3.77 ± 0.49
Globus Pallidus3.8 ± 0.59
Hypothalamus3.45 ± 0.39
Insula3.85 ± 0.38
Limbic Lobe4.1 ± 0.53
Mesencephalon3.93 ± 0.57
Myelencephalon3.95 ± 0.52
Occipital Lobe4.19 ± 0.6
Parietal Lobe3.89 ± 0.52
Pontine Tegmentum3.66 ± 0.56
Striatum3.94 ± 0.5
Subthalamus3.37 ± 0.94
Temporal Lobe3.9 ± 0.5
Thalamus3.74 ± 0.49
White Matter3.83 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CfpCBCerebellum10.13
11.05
CfpCTXCerebral cortex19.31
12.07
CfpHIPHippocampal region23.33
22.68
CfpHPFHippocampal formation19.96
17.24
CfpHYHypothalamus1.43
1.41
CfpLSXLateral septal complex3.15
2.06
CfpMBMidbrain7.94
10.15
CfpMYMedulla4.76
3.99
CfpOLFOlfactory bulb17.79
12.2
CfpPPons3.73
3.32
CfpPALPallidum1.6
1.35
CfpRHPRetrohippocampal region14.23
9.68
CfpsAMYStriatum-like amygdalar nuclei2.34
1.55
CfpSTRStriatum3.49
2.35
CfpSTRdStriatum dorsal region3.91
2.74
CfpSTRvStriatum ventral region3.24
1.96
CfpTHThalamus6.39
6.05
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024340 9 360 368 CAGQQQDIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018