AutismKB 2.0

Annotation Detail for PFDN5


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Basic Information Top
Gene Symbol:PFDN5 ( MGC5329,MGC71907,MM-1,MM1,PFD5 )
Gene Full Name: prefoldin subunit 5
Band: 12q13.13
Quick LinksEntrez ID:5204; OMIM: 604899; Uniprot ID:PFD5_HUMAN; ENSEMBL ID: ENSG00000123349; HGNC ID: 8869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst24 / 62319385
fetus104 / 564012184
neonate7 / 31097225
infant0 / 236200 
juvenile3 / 5555653
adult308 / 1939121158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor17 / 94178180
cervical tumor2 / 3436658
chondrosarcoma11 / 82823132
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor14 / 119369117
germ cell tumor12 / 26384545
glioma11 / 106883102
head and neck tumor46 / 136302337
kidney tumor3 / 6895943
leukemia15 / 95842156
liver tumor19 / 96359197
lung tumor10 / 10312796
lymphoma9 / 71755125
non-neoplasia2 / 9725020
normal503 / 3360307149
ovarian tumor18 / 76682234
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer14 / 102680136
retinoblastoma3 / 4635664
skin tumor20 / 124949160
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites3 / 4001574
bladder1 / 2975733
blood35 / 123478283
bone17 / 71655237
bone marrow21 / 48801430
brain70 / 110098963
cervix2 / 4817141
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue56 / 215722259
esophagus0 / 202090 
eye27 / 211054127
heart29 / 89626323
intestine20 / 23447285
kidney22 / 211777103
larynx4 / 24145165
liver41 / 207743197
lung49 / 336974145
lymph2 / 4427045
lymph node20 / 91610218
mammary gland18 / 153271117
mouth0 / 670520 
muscle18 / 107715167
nerve1 / 1576863
ovary20 / 102051195
pancreas20 / 21481293
parathyroid6 / 20539292
pharynx8 / 41328193
pituitary gland13 / 16585783
placenta26 / 28082592
prostate40 / 189345211
salivary gland3 / 20155148
skin22 / 210574104
spleen9 / 53952166
stomach14 / 96619144
testis24 / 33044272
thymus15 / 81131184
thyroid40 / 47473842
tonsil11 / 16999647
trachea2 / 5241338
umbilical cord7 / 13680511
uterus27 / 232878115
vascular17 / 51780328
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207132_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts1130
Adipocyte1009.2
AdrenalCortex914.85
Adrenalgland828.7
Amygdala542.25
Appendix1507.25
AtrioventricularNode219.7
BDCA4+_DentriticCells2029.85
Bonemarrow773.2
BronchialEpithelialCells1319.65
CD105+_Endothelial1497.3
CD14+_Monocytes3344.05
CD19+_BCells(neg._sel.)3826.35
CD33+_Myeloid2555.1
CD34+1618.1
CD4+_Tcells3535.4
CD56+_NKCells2157.75
CD71+_EarlyErythroid1464.95
CD8+_Tcells3076.25
CardiacMyocytes742.3
Caudatenucleus806.85
Cerebellum636.7
CerebellumPeduncles1168.9
CiliaryGanglion210.85
CingulateCortex719.15
Colorectaladenocarcinoma215.5
DorsalRootGanglion235.3
FetalThyroid1553.15
Fetalbrain1615.6
Fetalliver408.45
Fetallung1402.35
GlobusPallidus402.95
Heart952.95
Hypothalamus1616.1
Kidney709.05
Leukemia_chronicMyelogenousK-5621242.05
Leukemia_promyelocytic-HL-60882.95
Leukemialymphoblastic(MOLT-4)824.8
Liver491
Lung1219.3
Lymphnode1547.75
Lymphoma_burkitts(Daudi)1495.3
Lymphoma_burkitts(Raji)427.75
MedullaOblongata775.5
OccipitalLobe599.15
OlfactoryBulb920.7
Ovary1230.9
Pancreas850.65
PancreaticIslet1976.85
ParietalLobe507.65
Pituitary1883.45
Placenta881.85
Pons542.15
PrefrontalCortex1432.55
Prostate830.55
Salivarygland1006.2
SkeletalMuscle289.25
Skin369.25
SmoothMuscle1668.2
Spinalcord1237.9
SubthalamicNucleus583.75
SuperiorCervicalGanglion338.35
TemporalLobe1089.05
Testis1186.15
TestisGermCell1348.85
TestisIntersitial1224.35
TestisLeydigCell986.8
TestisSeminiferousTubule1129.3
Thalamus1051.05
Thymus1383.6
Thyroid1241.6
Tongue529.35
Tonsil1269.85
Trachea637.65
TrigeminalGanglion243.55
Uterus902.95
UterusCorpus1416.6
WholeBlood2260.35
Wholebrain947.7
colon635.15
pineal_day2128.6
pineal_night1902.26
retina1400.575
small_intestine747.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P128192
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.8 ± 0.23
Basal Forebrain10.94 ± 0.14
Basal Part of Pons10.73 ± 0.22
Cerebellar Cortex10.67 ± 0.17
Cerebellar Nuclei10.83 ± 0.3
Claustrum10.6 ± 0.22
Epithalamus10.97 ± 0.22
Frontal Lobe10.68 ± 0.26
Globus Pallidus11.49 ± 0.11
Hypothalamus10.96 ± 0.25
Insula10.69 ± 0.25
Limbic Lobe10.57 ± 0.24
Mesencephalon10.77 ± 0.29
Myelencephalon10.7 ± 0.27
Occipital Lobe10.51 ± 0.21
Parietal Lobe10.69 ± 0.25
Pontine Tegmentum10.75 ± 0.27
Striatum10.84 ± 0.26
Subthalamus10.68 ± 0.29
Temporal Lobe10.72 ± 0.25
Thalamus10.68 ± 0.24
White Matter11.31 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pfdn5CBCerebellum24.92
30.61
Pfdn5CTXCerebral cortex99.99
77.51
Pfdn5HIPHippocampal region52.73
83.81
Pfdn5HPFHippocampal formation57.84
70.31
Pfdn5HYHypothalamus87.15
74.71
Pfdn5LSXLateral septal complex100
85.58
Pfdn5MBMidbrain72.11
66.77
Pfdn5MYMedulla55.92
64.79
Pfdn5OLFOlfactory bulb82
65.73
Pfdn5PPons57.9
61.39
Pfdn5PALPallidum68.44
59.05
Pfdn5RHPRetrohippocampal region66.63
54.42
Pfdn5sAMYStriatum-like amygdalar nuclei69.31
54.92
Pfdn5STRStriatum60.72
44.4
Pfdn5STRdStriatum dorsal region49.33
36.35
Pfdn5STRvStriatum ventral region76.05
50.56
Pfdn5THThalamus64.03
59.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00070876 15 94 108 IQQLTALGAAQATAK Peptide Atlas
PFD5_HUMAN_0 0 0 0 NQLDQEVEFLSTSIAQLK PRIDE
PFD5_HUMAN_128 10 128 137 QAVMEMMSQK PRIDE
PFD5_HUMAN_138 15 138 152 IQQLTALGAAQATAK PRIDE
PFD5_HUMAN_138 16 138 153 IQQLTALGAAQATAKA PRIDE
PFD5_HUMAN_19 18 19 36 NQLDQEVEFLSTSIAQLK PRIDE
PFD5_HUMAN_47 8 47 54 DCLNVLNK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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