AutismKB 2.0

Annotation Detail for CDK14


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDK14 ( KIAA0834,PFTAIRE1,PFTK1 )
Gene Full Name: cyclin-dependent kinase 14
Band: 7q21.13
Quick LinksEntrez ID:5218; OMIM: 610679; Uniprot ID:CDK14_HUMAN; ENSEMBL ID: ENSG00000058091; HGNC ID: 8883
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus51 / 56401290
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor18 / 114246157
esophageal tumor2 / 17290115
gastrointestinal tumor1 / 1193698
germ cell tumor27 / 263845102
glioma4 / 10688337
head and neck tumor21 / 136302154
kidney tumor6 / 6895987
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia8 / 9725082
normal308 / 336030791
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder5 / 29757168
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain216 / 1100989196
cervix0 / 481710 
connective tissue7 / 14925546
ear3 / 16212185
embryonic tissue16 / 21572274
esophagus2 / 2020998
eye9 / 21105442
heart5 / 8962655
intestine24 / 234472102
kidney14 / 21177766
larynx3 / 24145124
liver7 / 20774333
lung19 / 33697456
lymph1 / 4427022
lymph node12 / 91610130
mammary gland8 / 15327152
mouth15 / 67052223
muscle7 / 10771564
nerve0 / 157680 
ovary0 / 1020510 
pancreas18 / 21481283
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta3 / 28082510
prostate14 / 18934573
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis32 / 33044296
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea46 / 52413877
umbilical cord0 / 136800 
uterus13 / 23287855
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204604_at
Cell line Expression level Expression bar
721_B_lymphoblasts87.85
Adipocyte16.5
AdrenalCortex15.9
Adrenalgland10.9
Amygdala216.75
Appendix21.1
AtrioventricularNode15.85
BDCA4+_DentriticCells15
Bonemarrow14.7
BronchialEpithelialCells12.05
CD105+_Endothelial12.85
CD14+_Monocytes12.85
CD19+_BCells(neg._sel.)119.6
CD33+_Myeloid16.9
CD34+16.1
CD4+_Tcells12.3
CD56+_NKCells13.85
CD71+_EarlyErythroid11.95
CD8+_Tcells10.8
CardiacMyocytes26.05
Caudatenucleus29.65
Cerebellum28.7
CerebellumPeduncles30.15
CiliaryGanglion13.95
CingulateCortex154.9
Colorectaladenocarcinoma12.15
DorsalRootGanglion12.8
FetalThyroid16.75
Fetalbrain77.3
Fetalliver12.5
Fetallung16.4
GlobusPallidus71.15
Heart22.85
Hypothalamus112.4
Kidney20.75
Leukemia_chronicMyelogenousK-56211.75
Leukemia_promyelocytic-HL-6092.6
Leukemialymphoblastic(MOLT-4)9.7
Liver19.6
Lung14.55
Lymphnode21.3
Lymphoma_burkitts(Daudi)114.6
Lymphoma_burkitts(Raji)41.15
MedullaOblongata86.55
OccipitalLobe107.75
OlfactoryBulb11
Ovary10.65
Pancreas11.9
PancreaticIslet16.75
ParietalLobe75.3
Pituitary56.05
Placenta14.25
Pons63.5
PrefrontalCortex506.95
Prostate29.55
Salivarygland19.6
SkeletalMuscle18.1
Skin11.45
SmoothMuscle121.5
Spinalcord27.5
SubthalamicNucleus135.25
SuperiorCervicalGanglion39.05
TemporalLobe113.45
Testis13.95
TestisGermCell14.8
TestisIntersitial11.1
TestisLeydigCell14.7
TestisSeminiferousTubule14.95
Thalamus143.25
Thymus9.4
Thyroid27.1
Tongue15.75
Tonsil14.7
Trachea12.95
TrigeminalGanglion42.3
Uterus14.9
UterusCorpus17.4
WholeBlood18.15
Wholebrain37.7
colon14.95
pineal_day17.04
pineal_night16.84
retina29.925
small_intestine12.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P145889
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.12 ± 0.39
Basal Forebrain10.48 ± 0.29
Basal Part of Pons11.51 ± 0.26
Cerebellar Cortex11.08 ± 0.16
Cerebellar Nuclei10.22 ± 0.45
Claustrum11.33 ± 0.38
Epithalamus10.5 ± 0.58
Frontal Lobe11.08 ± 0.51
Globus Pallidus9.7 ± 0.44
Hypothalamus10.5 ± 0.63
Insula10.95 ± 0.17
Limbic Lobe11.29 ± 0.44
Mesencephalon10.89 ± 0.7
Myelencephalon10.92 ± 0.5
Occipital Lobe11.53 ± 0.35
Parietal Lobe11.27 ± 0.37
Pontine Tegmentum10.86 ± 0.43
Striatum10.16 ± 0.54
Subthalamus11.15 ± 0.15
Temporal Lobe11.1 ± 0.28
Thalamus11.07 ± 0.38
White Matter9.11 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pftk1CBCerebellum22.87
40.71
Pftk1CTXCerebral cortex93.63
93.16
Pftk1HIPHippocampal region91.88
100
Pftk1HPFHippocampal formation93.21
100
Pftk1HYHypothalamus34.44
33.94
Pftk1LSXLateral septal complex15.98
14.22
Pftk1MBMidbrain48.06
55.61
Pftk1MYMedulla51.76
76.27
Pftk1OLFOlfactory bulb72.86
78.63
Pftk1PPons58.98
83.62
Pftk1PALPallidum30.87
39.26
Pftk1RHPRetrohippocampal region95.7
100
Pftk1sAMYStriatum-like amygdalar nuclei38.2
38.29
Pftk1STRStriatum12.67
13.13
Pftk1STRdStriatum dorsal region8.39
9.14
Pftk1STRvStriatum ventral region9.56
10.04
Pftk1THThalamus76.2
85.5
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved