AutismKB 2.0

Annotation Detail for PIK3CG


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Basic Information Top
Gene Symbol:PIK3CG ( PI3CG,PI3K,PI3Kgamma,PIK3 )
Gene Full Name: phosphoinositide-3-kinase, catalytic, gamma polypeptide
Band: 7q22.3
Quick LinksEntrez ID:5294; OMIM: 601232; Uniprot ID:PK3CG_HUMAN; ENSEMBL ID: ENSG00000105851; HGNC ID: 8978
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal17 / 33603075
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow3 / 4880161
brain3 / 11009892
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis8 / 33044224
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206369_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.85
Adipocyte4.4
AdrenalCortex4.65
Adrenalgland3.8
Amygdala4.75
Appendix4.6
AtrioventricularNode3.6
BDCA4+_DentriticCells30.65
Bonemarrow4.5
BronchialEpithelialCells4.4
CD105+_Endothelial4.5
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid8.45
CD34+5.75
CD4+_Tcells5.3
CD56+_NKCells27.45
CD71+_EarlyErythroid4.2
CD8+_Tcells5.2
CardiacMyocytes6.2
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.3
CingulateCortex4.6
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.45
FetalThyroid4.4
Fetalbrain4.5
Fetalliver4
Fetallung3.65
GlobusPallidus3.3
Heart6.05
Hypothalamus4.75
Kidney4
Leukemia_chronicMyelogenousK-5624.05
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.65
Liver6.35
Lung4.95
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.9
Lymphoma_burkitts(Raji)6.55
MedullaOblongata4.15
OccipitalLobe4
OlfactoryBulb3.5
Ovary3.05
Pancreas3.6
PancreaticIslet4.75
ParietalLobe4.75
Pituitary5.25
Placenta4.55
Pons4.3
PrefrontalCortex5.55
Prostate5.3
Salivarygland3.8
SkeletalMuscle5.4
Skin3.6
SmoothMuscle5.05
Spinalcord4.8
SubthalamicNucleus4.1
SuperiorCervicalGanglion5.15
TemporalLobe4.1
Testis3.85
TestisGermCell3.7
TestisIntersitial3.75
TestisLeydigCell4.45
TestisSeminiferousTubule3.85
Thalamus4.6
Thymus3.5
Thyroid5.65
Tongue4.5
Tonsil4.35
Trachea3.75
TrigeminalGanglion4.45
Uterus3.6
UterusCorpus4
WholeBlood11.25
Wholebrain3.75
colon4.5
pineal_day5.52
pineal_night5.36
retina5.375
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_510_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.43 ± 1.18
Basal Forebrain2.59 ± 0.21
Basal Part of Pons2.62 ± 0.47
Cerebellar Cortex2.47 ± 0.6
Cerebellar Nuclei3.22 ± 0.56
Claustrum3.75 ± 0.67
Epithalamus2.93 ± 0.79
Frontal Lobe3.27 ± 0.71
Globus Pallidus3.55 ± 0.86
Hypothalamus3.04 ± 0.82
Insula3.38 ± 0.62
Limbic Lobe2.93 ± 0.73
Mesencephalon3.1 ± 0.73
Myelencephalon2.93 ± 0.68
Occipital Lobe2.53 ± 0.72
Parietal Lobe2.87 ± 0.76
Pontine Tegmentum3.06 ± 0.9
Striatum2.67 ± 0.73
Subthalamus3.46 ± 1.08
Temporal Lobe2.69 ± 0.75
Thalamus2.85 ± 0.76
White Matter3.35 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pik3cgCBCerebellum0
0
Pik3cgCTXCerebral cortex0
0
Pik3cgHIPHippocampal region0
0
Pik3cgHPFHippocampal formation0
0
Pik3cgHYHypothalamus0
0
Pik3cgLSXLateral septal complex0
0
Pik3cgMBMidbrain0
0
Pik3cgMYMedulla0
0
Pik3cgOLFOlfactory bulb0
0
Pik3cgPPons0
0
Pik3cgPALPallidum0
0
Pik3cgRHPRetrohippocampal region0
0
Pik3cgsAMYStriatum-like amygdalar nuclei0
0
Pik3cgSTRStriatum0
0
Pik3cgSTRdStriatum dorsal region0
0
Pik3cgSTRvStriatum ventral region0
0
Pik3cgTHThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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