AutismKB 2.0

Annotation Detail for ACP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACP2 ( - )
Gene Full Name: acid phosphatase 2, lysosomal
Band: 11p11.2
Quick LinksEntrez ID:53; OMIM: 171650; Uniprot ID:PPAL_HUMAN; ENSEMBL ID: ENSG00000134575; HGNC ID: 123
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus69 / 564012122
neonate29 / 31097932
infant7 / 23620296
juvenile33 / 55556593
adult253 / 1939121130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor43 / 94178456
cervical tumor8 / 34366232
chondrosarcoma6 / 8282372
colorectal tumor7 / 11424661
esophageal tumor7 / 17290404
gastrointestinal tumor21 / 119369175
germ cell tumor80 / 263845303
glioma21 / 106883196
head and neck tumor4 / 13630229
kidney tumor24 / 68959348
leukemia7 / 9584273
liver tumor30 / 96359311
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia55 / 97250565
normal696 / 3360307207
ovarian tumor9 / 76682117
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS44 / 125680350
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland22 / 33197662
ascites4 / 4001599
bladder9 / 29757302
blood33 / 123478267
bone4 / 7165555
bone marrow2 / 4880140
brain306 / 1100989277
cervix9 / 48171186
connective tissue69 / 149255462
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus10 / 20209494
eye9 / 21105442
heart9 / 89626100
intestine39 / 234472166
kidney68 / 211777321
larynx0 / 241450 
liver41 / 207743197
lung46 / 336974136
lymph0 / 442700 
lymph node14 / 91610152
mammary gland45 / 153271293
mouth5 / 6705274
muscle5 / 10771546
nerve0 / 157680 
ovary13 / 102051127
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta37 / 280825131
prostate38 / 189345200
salivary gland1 / 2015549
skin26 / 210574123
spleen30 / 53952556
stomach11 / 96619113
testis66 / 330442199
thymus25 / 81131308
thyroid2 / 4747342
tonsil0 / 169990 
trachea17 / 52413324
umbilical cord4 / 13680292
uterus48 / 232878206
vascular15 / 51780289
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202767_at
Cell line Expression level Expression bar
721_B_lymphoblasts37.1
Adipocyte60.1
AdrenalCortex76.1
Adrenalgland132.45
Amygdala90.6
Appendix60.8
AtrioventricularNode45.3
BDCA4+_DentriticCells51.95
Bonemarrow66.95
BronchialEpithelialCells58.6
CD105+_Endothelial48.25
CD14+_Monocytes111.3
CD19+_BCells(neg._sel.)30.2
CD33+_Myeloid95.3
CD34+114.95
CD4+_Tcells50.5
CD56+_NKCells85.45
CD71+_EarlyErythroid56.2
CD8+_Tcells45.05
CardiacMyocytes94.65
Caudatenucleus54.55
Cerebellum62.6
CerebellumPeduncles69.15
CiliaryGanglion43.35
CingulateCortex89.3
Colorectaladenocarcinoma63.9
DorsalRootGanglion47
FetalThyroid58.65
Fetalbrain58.2
Fetalliver77.4
Fetallung50.15
GlobusPallidus44.55
Heart92.3
Hypothalamus90.65
Kidney100.3
Leukemia_chronicMyelogenousK-56254.65
Leukemia_promyelocytic-HL-6051.7
Leukemialymphoblastic(MOLT-4)48.25
Liver905.55
Lung250.55
Lymphnode84.35
Lymphoma_burkitts(Daudi)77
Lymphoma_burkitts(Raji)57.9
MedullaOblongata81.95
OccipitalLobe54.4
OlfactoryBulb47.85
Ovary37.85
Pancreas54.45
PancreaticIslet88.65
ParietalLobe64.1
Pituitary84.55
Placenta421.55
Pons57.8
PrefrontalCortex83.15
Prostate307.75
Salivarygland55.9
SkeletalMuscle74.1
Skin44.95
SmoothMuscle68.9
Spinalcord66.2
SubthalamicNucleus55.95
SuperiorCervicalGanglion68.1
TemporalLobe58.35
Testis73.85
TestisGermCell54.65
TestisIntersitial50.65
TestisLeydigCell59.8
TestisSeminiferousTubule57.45
Thalamus62.6
Thymus79.05
Thyroid104.1
Tongue58.75
Tonsil59.4
Trachea95.1
TrigeminalGanglion59.1
Uterus46.1
UterusCorpus54.85
WholeBlood75.8
Wholebrain219.75
colon70.2
pineal_day222.22
pineal_night240.9
retina102.95
small_intestine119.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_789_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.2 ± 0.44
Basal Forebrain3.91 ± 0.46
Basal Part of Pons3.74 ± 0.47
Cerebellar Cortex3.99 ± 0.42
Cerebellar Nuclei3.97 ± 0.6
Claustrum4.3 ± 0.86
Epithalamus3.36 ± 0.29
Frontal Lobe3.85 ± 0.53
Globus Pallidus4.26 ± 0.66
Hypothalamus3.7 ± 0.42
Insula4.05 ± 0.24
Limbic Lobe4.13 ± 0.58
Mesencephalon4 ± 0.51
Myelencephalon4 ± 0.58
Occipital Lobe4.11 ± 0.58
Parietal Lobe4.11 ± 0.6
Pontine Tegmentum3.93 ± 0.6
Striatum3.83 ± 0.68
Subthalamus3.7 ± 0.32
Temporal Lobe3.94 ± 0.61
Thalamus4.05 ± 0.52
White Matter3.69 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acp2CBCerebellum0.67
1.08
Acp2CTXCerebral cortex3.01
2.9
Acp2HIPHippocampal region18.85
24.68
Acp2HPFHippocampal formation16.53
19.26
Acp2HYHypothalamus13.66
13.19
Acp2LSXLateral septal complex0.48
1.33
Acp2MBMidbrain0.72
1.2
Acp2MYMedulla0.58
1.17
Acp2OLFOlfactory bulb11.14
9.9
Acp2PPons2.24
5.05
Acp2PALPallidum5.13
6.15
Acp2RHPRetrohippocampal region12.62
11.66
Acp2sAMYStriatum-like amygdalar nuclei13.67
10.66
Acp2STRStriatum3.7
3.13
Acp2STRdStriatum dorsal region0.8
0.68
Acp2STRvStriatum ventral region7.6
6.26
Acp2THThalamus9.86
10.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001267 8 349 356 CPLQDFLR Peptide Atlas
PPAL_HUMAN_110 20 110 129 TLMSAEANLAGLFPPNGMQR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved