AutismKB 2.0

Annotation Detail for PIP


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Basic Information Top
Gene Symbol:PIP ( GCDFP-15,GCDFP15,GPIP4 )
Gene Full Name: prolactin-induced protein
Band: 7q34
Quick LinksEntrez ID:5304; OMIM: 176720; Uniprot ID:PIP_HUMAN; ENSEMBL ID: ENSG00000159763; HGNC ID: 8993
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal123 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye35 / 211054165
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate21 / 189345110
salivary gland15 / 20155744
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206509_at
Cell line Expression level Expression bar
721_B_lymphoblasts24
Adipocyte54.95
AdrenalCortex49
Adrenalgland38.05
Amygdala45.65
Appendix48.55
AtrioventricularNode51.75
BDCA4+_DentriticCells31.7
Bonemarrow44.5
BronchialEpithelialCells43.05
CD105+_Endothelial23
CD14+_Monocytes20.9
CD19+_BCells(neg._sel.)30
CD33+_Myeloid32.15
CD34+27.3
CD4+_Tcells37.75
CD56+_NKCells29.4
CD71+_EarlyErythroid33.85
CD8+_Tcells31.95
CardiacMyocytes42.1
Caudatenucleus45.75
Cerebellum60.2
CerebellumPeduncles51.55
CiliaryGanglion46.75
CingulateCortex47.7
Colorectaladenocarcinoma40.1
DorsalRootGanglion39.65
FetalThyroid46.2
Fetalbrain43.6
Fetalliver51.75
Fetallung36.2
GlobusPallidus36.4
Heart64.4
Hypothalamus48.15
Kidney38.55
Leukemia_chronicMyelogenousK-56239.8
Leukemia_promyelocytic-HL-6037.5
Leukemialymphoblastic(MOLT-4)35.2
Liver101.15
Lung45.4
Lymphnode41.75
Lymphoma_burkitts(Daudi)51.65
Lymphoma_burkitts(Raji)60.95
MedullaOblongata40.4
OccipitalLobe39.85
OlfactoryBulb39.95
Ovary38.7
Pancreas35.55
PancreaticIslet47.65
ParietalLobe50.15
Pituitary71.9
Placenta45.3
Pons61.45
PrefrontalCortex55.6
Prostate639.5
Salivarygland17787.75
SkeletalMuscle57.65
Skin605.9
SmoothMuscle50.45
Spinalcord47.6
SubthalamicNucleus40.85
SuperiorCervicalGanglion57.4
TemporalLobe40.55
Testis55
TestisGermCell37.3
TestisIntersitial37.15
TestisLeydigCell44
TestisSeminiferousTubule38.2
Thalamus218.35
Thymus47.25
Thyroid229.7
Tongue44.85
Tonsil42.9
Trachea10084.25
TrigeminalGanglion49.2
Uterus35.85
UterusCorpus40.25
WholeBlood48.9
Wholebrain36.15
colon27.45
pineal_day44.62
pineal_night37.3
retina56.625
small_intestine30.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8955_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.67 ± 0.96
Basal Forebrain3.97 ± 0.53
Basal Part of Pons3.44 ± 0.8
Cerebellar Cortex3.28 ± 0.75
Cerebellar Nuclei3.93 ± 0.64
Claustrum4.11 ± 0.94
Epithalamus2.77 ± 0.8
Frontal Lobe3.5 ± 0.76
Globus Pallidus3.99 ± 0.67
Hypothalamus3.13 ± 0.82
Insula3.2 ± 0.68
Limbic Lobe3.53 ± 0.81
Mesencephalon3.83 ± 0.65
Myelencephalon3.67 ± 0.83
Occipital Lobe3.56 ± 0.83
Parietal Lobe3.57 ± 0.75
Pontine Tegmentum3.56 ± 0.72
Striatum3.94 ± 0.65
Subthalamus3.51 ± 0.53
Temporal Lobe3.45 ± 0.76
Thalamus3.82 ± 0.71
White Matter3.99 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PipCBCerebellum0
0
PipCTXCerebral cortex0
0
PipHIPHippocampal region0
0
PipHPFHippocampal formation0
0
PipHYHypothalamus0
0
PipLSXLateral septal complex0
0
PipMBMidbrain0
0
PipMYMedulla0
0
PipOLFOlfactory bulb0
0
PipPPons0
0
PipPALPallidum0
0
PipRHPRetrohippocampal region0
0
PipsAMYStriatum-like amygdalar nuclei0
0
PipSTRStriatum0
0
PipSTRdStriatum dorsal region0
0
PipSTRvStriatum ventral region0
0
PipTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00037976 19 45 63 SVRPNDEVTAVLAVQTELK Peptide Atlas
PIP_HUMAN_0 0 0 0 TVQIAAVVDVIR PRIDE
PIP_HUMAN_119 15 119 133 ELGICPDDAAVIPIK PRIDE
PIP_HUMAN_137 8 137 144 FYTIEILK PRIDE
PIP_HUMAN_2 8 2 9 RLLQLLFR PRIDE
PIP_HUMAN_70 16 70 85 TYLISSIPLQGAFNYK PRIDE
PIP_HUMAN_86 11 86 96 YTACLCDDNPK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018